Ograniczanie wyników

Czasopisma help
Autorzy help
Lata help
Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 44

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 3 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 3 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
Abstract. Vitamin K belongs to the family of fat-soluble vitamins and plays an important role in hemostasis, bone metabolism and may affect cerebral sphingolipid synthesis. It is a cofactor necessary for posttranslational γ-carboxylation of glutamyl residues in selected proteins such as the osteocalcin, and procoagulation factors II, VII, IX, X. Vitamin K deficient individuals appear to have more undercarboxylated proteins, which are functionally defective. The witamin K deficiency has been frequently documented in patients with cystic fibrosis. The main possible causes of this deficiency include: fat malabsorption due to pancreatic exocrine insufficiency, cholestatic or noncholestatic liver disease, reduced production of vitamin K by colonic flora related to chronic antibiotic treatments, bowel resections and increased mucous accumulation in the bowel. CF patients are more prone to osteopenia, caused by chronic vitamin K shortage, than to coagulopathy. Despite available evidence, which strongly suggests that all CF patients are at risk for developing vitamin K deficiency, its supplementation doses have not been established. Recent recom- mendations from Europe and the UK have suggested varied doses ranging from 0.3 mg/day to 10 mg/week. Further studies, both cross sectional and longitudinal interventional, are still required to determine routine and therapeutic supplementation doses.
Background. Human milk contains considerable number of growth factors, including epidermal growth factor (EGF) and insulin-like growth factor-1 (IGF-1). There are no data comparing the EGF and IGF-1 levels in the serum and milk of breast-feeding women. Therefore, the aim of our study was to assess a possible relationship between the concentrations of these growth factors. Material and methods. Thirty-nine women in child-birth were included in the study. Ali women provided blood and milk samples during the first six hours after delivery. EGF (by immunoenzymatic method) and IGF-1 (by radioimmunossay method) concentrations were measured in both media. Results. EGF breast milk concentrations ranged from 3.18 to 4.51 ng/ml and on average were significantly higher (p < 0.0001) than those found in the women’s serum (front 0.02 to 0.13 ng/ml). The opposite distribution was found for IGF-1 levels. Its milk concentrations ranged from 8.8 to 61.9 ng/ml and on average were significantly lower (p < 0.0001) than the serum concentrations (from 192.6 to 595.3 ng/ml). No correlation was found between the serum and milk concentrations of both growth factors. Conclusion. EGF seems to be synthesized locally in mammary glands, whereas IGF-1 probably permeates into the milk from the vascular bed.
Introduction and objective. Phytoestrogens are one of nutritional factors exhibiting a chemoprotective action, potentially reducing vasomotor symptoms as well as cancerous lesions. The study was ocused on an association between the consumption of phytoestrogens in the diet, blood serum cholesterol concentration and urinary estrogen metabolites levels. Materials and methods. The study was conducted on 55 women in the perimenopausal period, who were characterized by an increased risk of hormone-dependent cancer. Energy and nutritive value of food rations, and especially the level of phytoestrogen consumption in the diets in the examined population, were analyzed using the Wikt Pro computer programme. Estrogen metabolites (2OHE, 16α-OHE1) were determined from 24‑urine samples by the ELISA method. The EMR index was calculated. Plasma total cholesterol concentrations was measured. Results and conclusions. The population with a higher consumption of phytoestrogens and dietary fibre in the diet, at the simultaneous slight limitation of energy value of the food ration, is characterized by an improved blood serum cholesterol concentration and an appropriate estrogen metabolism towards a significant increase in the estrogen index for the cancer lesions in the mammary glands.
 Introduction: Hydrogen breath test (BT) is commonly used as a diagnostic tool for the detection of small intestine bacterial overgrowth (SIBO). It was reported that colonic methane production is far more frequent in cystic fibrosis (CF) patients than in other subjects. Therefore, measuring exclusively hydrogen in the diagnostic breath test for diagnosing SIBO might be of limited value. We aimed to assess the usefulness of combined measurement of hydrogen and methane expiration for the diagnosis of SIBO in CF. Material and Methods: The study comprised 62 CF patients aged 5 to 18 years. Three-hundred-ninety subjects assessed due to gastrointestinal symptoms for the presence of SIBO served as a comparative group. In all subjects hydrogen/methane BT using glucose was performed. A positive BT was defined as fasting hydrogen ≥ 20 ppm or fasting methane ≥ 10 ppm or a rise of ≥ 12 ppm hydrogen or ≥ 6 ppm methane over baseline during the test. Results: In 23 (37.1%) CF patients and in 52 (13.3%) subjects from the comparative group abnormal BT results were found. In seven (11.3%) CF patients and 29 (7.4%) of the other subjects studied methane measurement allowed diagnosis of SIBO. Conclusions: Small intestine bacterial overgrowth is frequent in cystic fibrosis. For its detection in cystic fibrosis and other gastrointestinal patients, combined hydrogen and methane measurement instead of hydrogen breath test should be applied. Without the additional measurement of methane a significant percentage of SIBO will be missed.
Badania podjęto w celu określenia wpływu zmian w spożyciu składników odżywczych przez młode dorosłe osoby, po zmianie modelu żywienia z tradycyjnego na wegetariański. Objęto nimi 21 osób, o średnim wieku 24,0±2,9 lat. Oceniono spożycie składników odżywczych podczas żywienia zwyczajowego, a następnie po 4 tygodniach stosowania wegetariańskiego modelu odżywiania (laktoowowegetariańskiego lub wegańskiego). Zmiana modelu żywienia z tradycyjnego na wegetariański była w ograniczonym stopniu związana z potencjalnym korzystnym wpływem na zdrowie. Pożądane zmiany dotyczyły jedynie zwiększenia spożycia węglowodanów ogółem oraz zmniejszenia spożycia tłuszczu, cholesterolu i fosforu. Zmiana modelu żywienia wpłynęła na dalsze zmniejszenie spożycia witamin z grupy В i cynku, natomiast nie zmieniło się spożycie magnezu i potasu oraz błonnika i witamin o właściwościach anty oksydacyjnych. Realizowany wegetariański model żywienia nie posiadał większości charakterystycznych cech prozdrowotnych, zmniejszających ryzyko chorób cywilizacyjnych.
Badaniami objęto 21 młodych, dorosłych osób (15 kobiet і 6 mężczyzn), o średnim wieku 24,0±2,9 lat. Masę i skład ciała oceniono podczas żywienia zwyczajowego, a następnie po 30 dniach stosowania wegetariańskiego modelu odżywiania (laktoowowegetariańskiego lub wegańskiego). W ocenie wykorzystano podstawowe parametry antropometryczne: masę i wysokość ciała, obwody talii i bioder, wskaźnik T/B, BMI, obwód mięśni ramienia (AMC), beztłuszczową masę ciała (FFM), masę tłuszczu (FM) i odsetek tłuszczu w ciele (%FM). Po zmianie modelu żywienia z tradycyjnego na wegetariański u kobiet stwierdzono istotne zmniejszenie masy ciała o 1,3kg, obwodu talii o 1,6cm, wskaźnika T/B o 0,02 jedn., BMI o 0,5kg/nf, FM o 1,8kg i %FM 2,4 jedn%. U mężczyzn wykazano zmniejszenie obwodu ramienia o 0,8cm, FM o l,6kg i %FM o 2,1%. Zmiana modelu żywienia z tradycyjnego na wegetariański wpłynęła na zmniejszenie ilości tkanki tłuszczowej, jednak bez zmian w zawartości tkania mięśniowej. Odnotowane pozytywne aspekty odżywiania wegetariańskiego mogą być związane z korzystną strukturą spożycia energii oraz tendencją do zmniejszonej wartości energetycznej racji pokarmowych.
Abstract. Lactase-phlorizin hydrolase (LCT), more commonly known as lactase, is an enzyme responsible for cleaving lactose into absorbable monosaccharides, glucose and galactose. LCT deficiency (hypolactasia - HL) is caused by a decreased activity of LCT in the small intestinal villi and potentially results in lactose malabsorption what may lead to the development of clinical symptoms (diarrhea, bloating, flatulence and cramps) and avoiding milk products in the diet. HL is the world's most common enzyme deficiency in humans. HL exists in three distinct forms - congenital, primary and secondary. Adult type hypolactasia (ATH) is the most common phenotype found in human. It is a genetically predetermined physiological condition inherited through an autosomal recessive mode which results in a decline of lactase activity after weaning. ATH is associated with the LCT -13910 C>T polymorphism worldwide, except in Africa. Lactase non-persistence has been observed in individuals with the C/C-13910 genotype, whereas lactase persistence in subjects with remaining allelic variants. Small intestine biopsy is the only diagnostic procedure allowing for the direct measurement of LCT activity, however due to its invasive nature it is hardly accepted by patients. Therefore, LCT status is often inferred simply by assessing the patient's lactose digestion. A lactose tolerance test can be performed after lactose load and then measuring blood glucose concentration or breath hydrogen (preferably hydrogen and methane) expiration. A genetic test of the C/T-13910 polymorphism is also available at present. It is a reliable method in excluding/confirming ATH predisposition. However, it definitely does not assess lactose tolerance or malabsorption.
Background. There are no long-term prospective studies assessing the impact of the vegan diet on vitamin B-12 (B-12) status. Many vegans take B-12 supplements irregularly or refuse to adopt them at all, considering them to be “unnatural” products. The use of B-12 fortified food may be an altemative. Therefore, we aimed to estimate the long-term effect of a vegan diet on serum B-12 concentrations in healthy omnivore adults, comparing the influence of natural products consumption and B-12 fortified food. Material and methods. A five year prospective study was carried out comprising 20 omnivore healthy adult subjects, who moved to strict vegan diet for 5 years. Ten volunteers followed vegan diet based entirely on natural products, while the remaining ten subjects consumed food fortified in B-12. In all subjects serum vitamin B-12 concentration was determined before and 6, 12, 24 and 60 months after the implementation of the diet. Results. A significant decrease (p < 0.0002) of serum B-12 concentrations in the whole studied group was noted after 60 months of vegan diet. However, observed changes were in fact limited to the subgroup consuming exclusively natural products (p < 0.0001). Conclusions. Transition from omnivore to vegan diet is associated with the risk of vitamin B-12 deficiency. B-12 fortified products might constitute a valuable altemative in vegans refiising to take vitamin supplements.
Background. The aim of this study was to assess the influence of the consumption level of plant sterols naturally occurring in diet on the lipid profile in obese women with dyslipidemia. Materiał and methods. The study population was primarily comprised of 120 obese women aged over 55 from Poland, with twenty seven subjects dropping out of the study due to the inclusion and exclusion criteria. Anthropometric appraisal included body height and weight, as well as waist and hip circumferences. Lipid profile was determined by commercially available enzymatic methods. Nutritional data, including plant sterols intake were assessed by 7-day food records. Results. The multiple linear regression, adjusted for age, height, Body Mass Index and Waist to Hip Ratio, showed the relation of polyunsaturated fatty acids with LDL-cholesterol concentration (p < 0.05). Natural plant sterols intake was estimated at Median = 146 mg/day. The correlation between LDL-cholesterol concentration and plant sterols intake was not statistically significant (p > 0.05). Condusions. The results of this study suggest that consumption of naturally-occurring polyunsaturated fatty acids and not plant sterols is connected with lower LDL-cholesterol concentration in obese women.
Background. Anthropometric parameters provide a lot of information about body composition and nutritional status, regardless whether they relate to obesity or malnutrition. The aim of this study was to assess the relationship between nutritional status, dietary habits and body image perception among male Polish adolescents. Material and methods. The study population primarily comprised 322 male adolescents aged 17-18 years from Western Poland, with thirty respondents however, dropping out of the study during its course. Anthropometric appraisal included body height and weight, four skinfolds thickness, circumferences of the waist, hip and arm. The percentage of fat mass and arm muscle area was calculated. The self-administrated questionnaires were used to estimate the frequency and quality of food intake, as well as the perception of body image of the studied subjects. In order to identify the similarity of nutritional habits and anthropometric parameters of adolescent males, cluster analysis was applied. Results. The mean values of body weight and height were close to 50th percentile. However, 10.7% of males were underweight, 10.7% overweight and 1.3% obese. The tendency to underestimate own level of fatness among overweight and obese subjects was observed. Over 90% of the studied subjects consider "average" silhouette as an ideal. Conclusions. Polish obese and overweight adolescents show a tendency to underestimate their level of fatness and perceive themselves as "average", despite possessing an excessive amount of body fat.
Przeprowadzone badania wykazały niski poziom spożycia węglowodanów przez ogół badanych i wysoki tłuszczów w racjach pokarmowych mężczyzn. Cechą charakterystyczną był brak zbilansowania pomiędzy Fe, Zn i Cu. Suplementacja diety cynkiem doprowadziła do statystycznie istotnego wzrostu poziomu cynku w surowicy, natomiast w przypadku erytrocytów, zmiany były statystycznie nieistotne.
The aim of this study was to assess the nutritional status and dietary habits among female adolescents. Four hundred seventy nine subjects aged from 17 to 18 years, from secondary schools of the Great Poland Region participated in the study. Anthropometric parameter measurements included those of body height and mass, skinfold thickness and circumferences of waist, hip and arm. The measurements served to calculate the percentage of fat mass and arm muscle area. Nutritional questionnaires were used to estimate the frequency and intake of selected food products. Mean values of body height and mass were approximately in the 50th percentile. However, 13.7% of females were underweight, 7.7% were overweight and 1.2% were obese. Cluster analysis resulted in 3 clusters, of which the second one showed the most detrimental nutritional habits. This cluster was characterised by the lowest intake of dairy products, fruits and vegetables, fish, meat and also by frequent long breaks between meals (longer than 5 hours). Improper nutritional behavior is a frequent finding in female adolescents, in Poland. Nevertheless, overweight and obesity are not more common than in other countries. Studies in this area should be continued and extended.
Badano wpływ suplemenatacji na profil kwasów tłuszczowych w fosfolipidach osocza krwi młodych kobiet i mężczyzn. Zaobserwowano statystycznie istotne zmiany w składzie kwasów tłuszczowych: spadek zawartości kwasów nasyconych i wzrost stężenia wielonienasyconych kwasów tłuszczowych. Suplementacja cynkiem dziennej racji pokarmowej osób zdrowych może wpływać na profil kwasów tłuszczowych, w tym również LCPUFA.
Przeprowadzona ocena sposobu żywienia grupy kobiet i mężczyzn wykazała zadowalającą podaż składników podstawowych błonnika oraz cynku. Oznaczone stężenia cynku w surowicy i erytrocytach odpowiadały wartościom średnim w populacji. Różnice pomiędzy oznaczonymi wartościami skrajnymi mogą sugerować występowanie ukrytych niedoborów tego pierwiastka w badanej populacji.
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 3 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.