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1994 | 21 | 2 |

Tytuł artykułu

Investigation of serum antioxidative vitamin level, the intensity of peroxidative processes and the effect of supplementation in patients with acute myocardial infarction

Warianty tytułu

PL
Badania nad zawartoscia witamin antyoksydacyjnych, intensywnoscia procesow peroksydacyjnych i wplywem suplementacji u pacjentow z klinicznym zawalem serca

Języki publikacji

EN

Abstrakty

EN
In patients with myocardial infarction and in control healthy subjects the serum conmiration of cuitioxidalive vitamins (tocopherol, ascorbic acid, retinol, carotenes) and of pid peroxides (TBA-RS) were determined. One group of the studied, patients besides roune treatment received orally ascorbic acid and d,l,α -tocopherol acetale αα 600 mg/day for 14 days, while the other placebo. An increased intensity of peroxidatire processes in the course of acute myocardial infarction and unsatisfactory serum antioxidative vitamin levels were found. Mean serum lipid peroxide level in non-supplemented group increased, in vitamin-supplemented group was supressed.
PL
U pacjentów z zawałem serca oraz osób kontrolnych oznaczano zawartość witamin antyoksydacyjnych (tokoferolu, kwasu askorbinowego, retinolu, karotenów) oraz stężenia nadtlenków lipidowych (TBA-RS). Część badanych pacjentów poza rutynowym leczeniem otrzymywała doustnie 600 mg kwasu askorbinowego i 600 mg octanu, d,l,α-tokoferolu, część placebo. Stwierdzono zwiększoną intensywność procesów peroksydacyjnych w przebiegu klinicznego zawału serca oraz niedostateczny stan odżywienia witaminami antyoksydacyjnymi.

Wydawca

-

Rocznik

Tom

21

Numer

2

Opis fizyczny

s.99-107,tab.,bibliogr.

Twórcy

  • Instytut Zywnosci i Zywienia, 02-903 Warszawa, ul.Powsinska 61/63
autor

Bibliografia

  • 1. Ardie N.G., Selley M.L., Simons L.A.: Platelet activation by oxidatively modified low density lipoproteins. Atherosclerosis 1989, 76, 117.
  • 2. Bessey O.A., Lowry O.H., Brock M.J., et al.: The determination of vitamin A and carotens in small quantities of blood serum. 1946, 166, 177.
  • 3. Bolton-Smith C., Woodward M., Tunstall-Pedoe H.: The Scotish Heart Health Study. Dietary intake by food frequency questionaire and odds rations for coronary heart disease risk. II. The antioxidant vitamins and fibre Eur. J. Clin. Nutr., 1992, 46, 85.
  • 4. Brückdorfer K.R.: Free radicals, lipid peroxidation and atherosclerosis: Current Opinion in Lipidology 1990, 1, 529.
  • 5. Buege J., Aust S.D.: Microsomal lipid peroxidations. Methods in enzymology. Ed. S. Fleicher, N.Y. Acad. Pres. 1978, vol. 52, p. 302.
  • 6. Duthie G.G., Wahle K.W.J., James W.P.T.: Oxidants, antioxidants and cardiovascular disease. Nutr. Res. Rev., 1989, 2, 51.
  • 7. Fisher F., Mc Lennan S.V., Heffernan T.H., et al.: Interaction of ascorbic acid and glucose on production of collagen and proteoglycans by fibroblast. Diabetes 1991, 40, 371-6.
  • 8. Frei B., England J., Ames B.: Ascorbate is an outstanding antioxidant in human blood. Proc. Natl.Acad. Sci., USA 1989, 86, 6377.
  • 9. Gaziano J.M., Manson J.E., Ridker P.M., et al.: Beta-carotene therapy for chronic stable angina. Circulation 1990, 82, Suppl. III, A - 796.
  • 10. Gey K.F.: Vitamin E and other essential antioxidants regarding coronary heart disease: Risk assessment studies. In Vitamin E in health and disease. Ed L. Packer 1993, Marcel Dekker Inc. USA.
  • 11.Görög P.G., Freeman A., Kakar U.V.: Lipid peroxides and atherosclerosis. Brit. Med. J., 1989, 298, 281.
  • 12. Gey K.F., Puska P., Jordan P., et al.: Inverse correlation between plasma vitamin E and mortality form ischemic heart disease in cross cultural epidemiology. Am. J. Clin. Nutr., 1991, 53, 326S.
  • 13. Gey K.F.: On the antioxidant hypothesis with regard to atherosclerosis. Bibl. Nutr. Dieta, 1986, 37, 53.
  • 14. Gey K.F., Brubacher G.B., Stächelin H.B.: Plasma levels of antioxidant vitamins in relation to heart disease and cancer. Am. J. Clin. Nutr. 1987, 1368.
  • 15. Herbaczyńska-Cedro K., Wartanowicz M., Panczenko-Kresowska B., et. al.: Inhibitory effect of vitamins C and E on the oxygen free radical production in human polymorphonuclear leucocytes: Eur. J. Clin. Investing., 1994, 24, 316.
  • 16. Hashim S.A., Schuttringer G.R.: Rapid determination of tocopherol in macro and micro quantities of plasma. Am. J. Clin. Nutr. 1966, 19, 137.
  • 17. Horwitt M.K., Harvey C.C., Dahn C.H. Jr., et al.: Relationship between tocopherol and serum lipid levels for determinations of nutritional adequancy. Am. N. Y. Acad. Sci., 1972, 203, 223.
  • 18. Iwama M., Honda A., Onohashi Y., et. al.: Alterations in glycosami- noglycans of the aorta of vitamin E deficient rats. Atherosclerosis 1985, 55, 115.
  • 19. Lenz M.L., Hughes H., Mitchel J.R., et. al.: Lipid hydroperoksy and hydroksy derivativs in ccoper catalysed oxidation of low density lipoprotein. J. Lipid Res., 1990 31, 1043.
  • 20. Lowry O.H., Lopez J.A., Bessey O.A.: The determination of ascorbic acid in small amounts of blood serum. J. Biol. Chem., 1945, 160, 600.
  • 21. Morel D.W., Di Corleto P.E., Chisolm G.M.: Endothelial and smooth muscle after low density lipoproteins in vitro by free radical oxidation. Arteriosclerosis 1984, 4, 357.
  • 22. Nutritional status: blood vitamins A, E, B6, B12, folic acid and carotene. Europ. J. Clin. Nutr., 1991, 45, 63.
  • 23. Noma A., Maeda S., Okuno M., et al.: Reduction of serum lipoprotein (a) in hyperlipidaemic patients with α -tocophenicotinate. Atherosclerosis 1990, 84, 213.
  • 24. Piotrowski J., Hunter G.C., Eskels C.D., et al.: Evidence for lipid peroxidation in atherosclerosis. Life Sci., 1990, 4, 715-21.
  • 25. Rath M., Pauling L.: Immunological evidence for the accumulation lipoprotein (a) in the atherosclerotic lession of the hypoascorbic guinea pig. Proc. Natl. Acad. Sci., USA 1990, 87, 9388.
  • 26. Riemersma R.A., Wood D.A., Macintyre C.A., et al.: Risk of angina pectoris and plasma concentration of vitamins A, C and E and carotene. The Lancet, 1991, vol. 337, 1.
  • 27. Panczenko-Kresowska B., Ziemlański Ś., Rudnicki St., el al.: Serum levels of lipid peroxides and antioxidative enzymes in patients after acute myocardial infraction. Żyw. Człow. Metab., 1992, 19, 2, 86.
  • 28. Quinn M.T., Partha Surathy S., Steinberg O.; Lysophosphatidylocholine: a chematactic factor for human monocytes and its potential role in atherogenesis. Proc. Natl. Acad. Sci., USA, 1988, 85, 2805.
  • 29. Stringer M.D., Görög P.G., Streeman H., et al.: Lipid peroxides and atherosclerosis. Brit. Med. J., 1989, 298, 281.
  • 30. Steinberg D., Pathasarathy S., Carew T.W., et al.: Modification of low density lipoprotein that increases its atherogenecity. New England J. Med., 1990, 320, 915.
  • 31. Salonen J.T., Salonen R., et al.: Low plasma beta-carotene, vitamin E and selenium levels associate with accelerated carotid atherogenesis in hypercholesterolemic men. 59th EAS Congress, 1992, may 17/21, Nice, France.
  • 32.Salonen J.T., Salonen R., Seppänen K., et al.: Effect of antioxidant supplementation on platelet function: a randomized poir matched, placebo-controlled, double blind trial in men with low antioxidant status. Am. Clin. Nutr., 1991, 53, 1222.
  • 33.Tubaro M., Cavallo G., Pensa V., et al.: Formation of hydroxyl radical in acute myocardial infraction in man. J. Mol. Cell. Cardiol., 1991, 23, Suppl. V, 26.
  • 34. Wartanowicz M., Panczenko-Kresowska B., Ziemlański Ś., et al.: The effect of alpha-tocopherol and ascorbic acid on the serum lipid peroxide level in elderly people. Ann. Nutr. Metab., 1984, 28, 186.
  • 35. Wartanowicz M., Ziemlański Ś., Rudnicki S.: Vitamin status of patients after heart attack. Żyw. Człow. Metab., 1992, 19,227.
  • 36. Van Gossum A., Kurian R., Whitwell J., et al.: Decrease in lipid peroxidation as measured by breath pentane output in normals after oral supplementation with vitamin. E. Clin, Nutr., 1988, 7, 53.
  • 37. Ziemlański Ś., Panczenko-Kresowska B., Bukowska H., et al.: Effects the beta-carotene on atherosclerosis in cholesterol fed guinea pigs. 62-nd EAS Congress. EuropeanAtherosclerosis Society, Jerusalem, September 5-9, 1993. Abstracts, p. 60.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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