Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 9

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
The aim of the retrospective study conducted over a period of five years was to assess the changes occurring in peroxidation processes in the blood of elderly people, and to find out possible correlations between the products of lipid peroxidation and the antioxidants, that is vitamins and enzymes with antioxidant activity. The study was carried out in a group of men and women born between 1921 and 1923. In 1992, 157 people (73 men and 84 women) participated in the study. In 1997 the second study was done on 103 people from the initial groups (43 men and 60 women). The concentration of lipid peroxides (TBARS), the activity of superoxide dismutase (SOD) and catalase (KAT) was measured in blood samples taken from an antecubital vein, from fasting subjects. Correlation coefficients were determined between TBARS, SOD, KAT and antioxidant vitamins and plasma lipids. It was found that over that period of five years the TBARS level decreased statistically significantly, on the average by 25%, in the plasma of men, and by 16% in that of women, as compared to the year 1992. SOD activity increased in blood haemolysates statistically significantly by 9% in men and by 22% in women. Over the same time period KAT activity decreased by 18% in men and by 11% women. A positive correlation was noted between TBARS and SOD activity both in 1992 and in 1997. TBARS level was negatively correlated with tocopherol level and cumulative antioxidant index in the blood of these subjects. In 1992 a positive correlation was demonstrated between TBARS and total cholesterol concentration. A positive correlation between TBARS and LDL-cholesterol was noted both in 1992 and 1997. During the five-year period of the study LDL-cholesterol level was positively correlated with SOD activity.
Celem pracy było zbadanie czy palmitynian retinylu redukuje stres oksydacyjny wywołany wysiłkiem fizycznym. Badania przeprowadzono na rosnących szczurach samcach rasy Wistar, które przez 10 dni biegały na bieżni z prędkością przesuwu 20 m/min. Szczurom podawano palmitynian retinylu w ilości 7,5, 15 lub 60 µg dziennie na zwierzą. Po tym okresie w osoczu oznaczano poziom retinolu, nadtlenki lipidowe i potencjał anty oksydacyjny oraz estry retinyłu w wątrobie. Stwierdzono, że palmitynian retinylu redukował stres oksydacyjny wywołany wysiłkiem fizycznym, a efektywność tego procesu nie zależała od dawki podanego palmitynianu.
The purpose of the study was determination of the effects of joint administration of antioxidant vitamins and mono and polyunsaturated fatty acids on the development of experimental atherosclerosis in rabbits. The experiment was carried out on 40 rabbits divided into 4 groups. Groups A, B, C, received stock diet with added cholesterol 0,2 g per 100 g of diet, in group B the diet was supplemented with rapaseed and sunflower oil besides cholesterol, group C was given 500 mg of vitamin C, 150 mg of vitamin E, 50 mg of beta-carotene besides cholesterol and oils per 100 g of diets. The control group - D, received stock diet with addition of the studied oils and vitamins. The experiment lasted 12 weeks. The mean area of lipid lesions in the aorta of the rabbits receiving the atherogenic diet was 18.1 ± 10.1%. The addition of vegetable oils to cholesterol-rich diet reduced this area to 14.0 ± 8.6%. The smallest lipid lesions (1.9 ± 1.3%) were in the animals receiving cholesterol-rich diet supplemented with antioxidant vitamins and vegetable oils. It was found also that cholesterol consumption was the highest in that group. The results of the experiment show that atherogenic processes in rabbits depend on many factors and are not directly proportional to the amount of cholesterol taken with diet and cholesterol concentration in serum.
The aim of the study was to investigate the effect of different dietary fats (sunflower oil, fish oil, lard) and their level in a diet (10% and 20% wt/wt), as well as different time of experimental diets administration (3 or 6 weeks) on plasma leptin level in Wistar rats. The type of dietary fat influenced significantly the plasma leptin concentration which was higher in groups receiving sunflower oil in a diet and lower in fish oil groups. There was a positive correlation between plasma leptin level and PUFA intake (r=0.371, p<0.003) and linoleic acid intake and its plasma level (r=0.462, p<0.0002 and r=0.381, p<0.005, respectively) as well as a negative correlation between plasma leptin and intake of docosahexaenoic acid and its plasma level (r=-0.360, p<0.004 and r=-0.360, p<0.008, respectively). There was no effect of the level of fat in a diet and time of experimental diets administration on plasma leptin, except of fish oil groups, where the concentration of the hormone decreased with an increasing level of this fat in a diet. It can be concluded that a change in the composition of dietary fatty acids can alter leptin production in adipose tissue.
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.