Ograniczanie wyników

Czasopisma help
Autorzy help
Lata help
Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 47

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 3 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych:  Toxocara
help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 3 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
Toxocariasis has been highlighted as a potentially important neglected infection of poverty in developed countries that experience substantive health disparities such as the United States. An association between Toxocara infection and lung function, in concert with a relatively high prevalence of infection, may mark an important mechanism by which this infection could contribute significantly to the differential morbidity across different socioeconomic groups and landscapes. To assess the potential relevance of this infection in a dense urban environment, we measured the association between forced expiratory volume in 1 second (FEV1) and serology diagnosed Toxocara infection in a sample of US-born New York City residents. We identified a significant independent association between Toxocara infection and lung function, wherein those with previous Toxocara infection had a 236.9 mL reduced FEV1 compared to those without Toxocara infection even after adjusting for age, sex, ethnicity, level of education, smoking status, body mass index, and pet ownership. These findings from New York City corroborate similar findings in a national sample and, while the cross-sectional data preclude a direct causal relationship, this study identifies a potentially important neglected infection in a dense urban landscape.
Soil contantination with Toxocara spp. eggs in the Katowice area and its environs. Toxocara spp. is a nematode which causes ,,larvae migrans visceralis'' syndrome in human, especially in children. Cats and dogs are the source of infective eggs of this parasite in human environment. The eggs appear in a soil of urban and rural areas in large number. We have investigated samples of a soil from the recreation areas in Katowice city and its suburbs. The goal of this study was to determine the degree of soil contamination with eggs of Toxocara spp. Of 157 samples examined 79 (50%) contained the eggs. The highest number of eggs has been found in samples collected from landscapes, particulary from the lawn and playgrounds.
The flotation method elaborated for recovery of Toxocara and other geohelminth eggs from soil is described. Soil samples of about 500 ml volume are picked from 3-cm superficial layer of the ground. In the laboratory, 40 g of dry and sifted material is analysed according to following procedure: 1 h standing, 20 minutes shaking and 3 minutes centrifugation (1500 rpm) in 5% sodium hydroxide (NaOH), then centrifugation, like above, with H₂O for washing the sample and next with the saturated sodium nitrate (NaNO₃) for flotation the eggs. Specimen is prepared by placing a cover slip on the positive meniscus of the flotation liquid.
Soil examinations made in 5 regions of Poland in the 1990s comprised 1184 samples taken from urban areas and 590 samples from suburban and rural areas. Toxocara spp. eggs were found more often in urban areas (14% positive samples) than in suburban and rural once (12% positive samples). The average ratio of positive samples was: in the streets and roads - 19,3% (0,36 eggs/100g of soil), near houses (backyards, gardens) - 18,6% (1,11 eggs/100g), in sandpits - 13,0% (0,23/100g), in parks and public gardens - 10,5% (0,46 eggs/100g), on playgrounds and playing fields 9,4% (0,06 eggs/100g) and on the beaches - 3,4% (0,03 eggs/100g). In children habitual play areas the prevalence of T. cati eggs was higher than T. canis eggs.
8
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Infekcje Toxocara w swietle materialow wlasnych

72%
Toxocarosis clinical forms wers diagnosed according to KRAUS et al. (1995). There were three forms: l) asymptomatic - marked by hypereosynophilia and ELISA positive serologic reaction, 2) minor - with cutaneous, pulmomary and pseudorheumatic lesions, 3) major – with hepatosplenomegaly and multifocal inflammatory lesions of organ or sight. Over the years of 1994-1997 in Infectious, Parasitic and Tropical Diseases clinic of the Voivodship Specialist Hospital of Łódź we found and treated 137 Toxocara canis cases. Among them 63 (46.0%) asymptomatic, 57 (42.6%) minor and 17 (12.4%) major forms were diagnosed. The disease was detected in 80 (58.4%) adults and 57 (41.6%) children. Seventy six patients lived i towns and 61 in country. Minor form patients had the symptoms as follows: skin allergy, large joints lesions, augmentation in lymph nodes. Radiology examinations revealed pulmonary lesions. Using ultrasonography there was found hepatosplenomegaly and changes echogenity in patiems with major form. Biochemical tests showed elevation in hepatic enzymes activity. Lesions of organ of sight were multifocal and usually included uveitis, retinitis, inflammation of anterior chamber and inflammation of vitreous body.
Infection with Trichinella spiralis in mice generates Th-2 mediated response, which controls effector mechanism operating in the intestine. It is associated with a pronounced intestinal mastocytosis, eosinophilia and destruction of intestinal epithelial layer during expulsion of parasite from the gut. It is believed that protection is dependent on non-specific inflammatory reaction mediated by mast cells. Furthermore, the higher serum levels of parasite specific IgG1 and IgG2a and also mucosal IgA response were related to the course of infection. Inhibition of humoral and cellular immune responses using ketotifen as anti-allergic compound, resulted in the greater worm burden and worm size, but not in the significant prolongation of intestinal phase. Moreover, in treated mice epithelial layer of the gut was protected from destruction provoked by the nematode. As interaction between effector leukocytes and antibodies were not effective it was proposed that other mechanisms, not related to hypersensitivity or conventional inflammatory response regulated the level of infection. The immunological and physiological phenomenons are discussed in terms of events associated with protection to the parasite. Possibly, immunoregulatory capasity of the nematode is involved in the induction of multiple mechanisms operated during infection.
16
72%
The distribution of Toxocara spp. eggs in Elbląg was studied. Out of 72 soil samples collected in public places of the city 13.9% were positive and the mean egg density was 3.75/100g soil. The city backyards were much more contaminated with Toxocara spp. Eggs (18.0%) than the playgrounds (4.5%). In sandpits examined the eggs were not found. Almost 80% of Toxocara spp. eggs recovered were infective. T. cali eggs were more frequent than T. canis eggs. Additionally in examined samples two eggs of Ancylostoma caninum and one egg of Ascaris lumbricoides were recognized.
Toxocarosis is still an important and actual problem in human medicine. It can manifest as visceral (VLM), ocular (OLM) or covert (CT) larva migrans syndroms. Complicated life cycle of Toxocara, lack of easy and practical methods of species differentiation of the adult nematode and embarrassing in recognition of the infection in definitive hosts create difficulties in fighting with the infection. Although studies on human toxocarosis have been continued for over 50 years there is no conclusive answer, which of species - T. canis or T. cati constitutes a greater risk of transmission of the nematode to man. Neither blood serological examinations nor microscopic observations of the morphological features of the nematode give the satisfied answer on the question. Since the 90-ths molecular methods were developed for species identification and became useful tools being widely applied in parasitological diagnosis. This paper cover the survey of methods of DNA analyses used for identification of Toxocara species. The review may be helpful for researchers focused on Toxocara and toxocarosis as well as on detection of new species. The following techniques are described: PCR (Polymerase Chain Reaction), RFLP (Restriction Fragment Length Polymorphism), RAPD (Random Amplified Polymorphic DNA) and SSCP (Single Strand Conformation Polymorphism).
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 3 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.