Wyniki wyszukiwania

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Interstitial cells of Cajal: is their role in gastrointestinal function in view of therapeutic perspectives underestimated or exaggerated?

100%

Timmermans J. P.

Folia Morphologica

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2001

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tom 60

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nr 1

This manuscript reviews the current views on morphology and function of the distinct subpopulations of interstitial cells of Cajal (ICC) in the digestive tract and their interrelationships with surrounding cells. Three different functions have been postulated so far, i.e. a pacemaker role, a mediator in enteric excitatory and inhibitory neurotransmission and a mechanosensor. Attention will also be paid to the interstitial cells of Cajal and their possible involvement in pathophysiological conditions. Finally, perspectives for interstitial cells of Cajal as targets for therapeutic intervention will be discussed.

2

Segmental distribution and morphometric features of primary sensory neurons projecting to the tibial periosteum in the rat

45%

Gajda M., Litwin J. A., Adriaensen D., Timmermans J. P., Cichocki T.

Folia Histochemica et Cytobiologica

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2004

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tom 42

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nr 2

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The distribution and chemical coding of neurons in the celiac-superior mesenteric ganglion complex supplying the normal and inflamed ileum in the pig

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Kaleczyc J., Pidsudko Z., Franke-Radowiecka A., Sienkiewicz W., Majewski M., Lakomy M., Timmermans J. P.

Polish Journal of Veterinary Sciences

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2004

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tom 07

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nr 3

The present study investigated the chemical coding of neurons in the celiac-superior mesenteric ganglion complex supplying the normal (n = 4) and inflamed (n=4) ileum (chemically-in- duced inflammation) in juvenile pigs using retrograde tracing combined with immunohistochem- istry. Ileum-projecting neurons (IPN) were predominantly distributed in the left and right superior mesenteric pools of the ganglion. The majority of them were adrenergic (tyrosine hydroxylase-positive) and also contained neuropeptide Y, somatostatin or galanin. No clear-cut differences in the distribution and chemical coding of IPN were found between normal and inflamed pigs. However, in the inflamed group, the density of peptidergic, IPN-associated nerve fibres was higher than that found in the control group.

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Neither axotomy nor target-tissue inflammation changes the NOS-or VIP-synthesis rate in distal bowel-projecting neurons of the porcine inferior mesenteric ganglion [IMG]

33%

Majewski M., Bossowska A., Gonkowski S., Wojtkiewicz J., Brouns I., Scheuermann D. W., Adriaensen D., Timmermans J. P.

Folia Histochemica et Cytobiologica

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2002

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tom 40

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nr 2

Ograniczanie wyników

2 Folia Histochemica et Cytobiologica

1 Folia Morphologica

1 Polish Journal of Veterinary Sciences

4 Timmermans J. P.

2 Adriaensen D.

2 Majewski M.

1 Bossowska A.

1 Brouns I.

1 Cichocki T.

1 Franke-Radowiecka A.

1 Gajda M.

1 Gonkowski S.

1 Kaleczyc J.

1 Lakomy M.

1 Litwin J. A.

1 Pidsudko Z.

1 Scheuermann D. W.

1 Sienkiewicz W.

1 Wojtkiewicz J.

2 2004

1 2002

1 2001

Interstitial cells of Cajal: is their role in gastrointestinal function in view of therapeutic perspectives underestimated or exaggerated?

Segmental distribution and morphometric features of primary sensory neurons projecting to the tibial periosteum in the rat

The distribution and chemical coding of neurons in the celiac-superior mesenteric ganglion complex supplying the normal and inflamed ileum in the pig

Neither axotomy nor target-tissue inflammation changes the NOS-or VIP-synthesis rate in distal bowel-projecting neurons of the porcine inferior mesenteric ganglion [IMG]