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Polsko-niemieckie stosunki gospodarcze na przykładzie krajów związkowych

100%

Kacprzak M., Stepniewska A.

Roczniki Naukowe Stowarzyszenia Ekonomistów Rolnictwa i Agrobiznesu

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2009

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tom 11

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nr 5

Członkostwo Polski w wielu organizacjach międzynarodowych jak np. OECD jest szansą dla utrzymania sprawnego systemu stosunków gospodarczych z innymi krajami. Położenie Niemiec w środku Europy sprzyja rozwojowi polsko-niemieckich stosunków gospodarczych, które nabrały nowego wymiaru po wejściu do UE. Przedsiębiorstwa obu krajów zaczęły konkurować ze sobą, zacieśniła się wymiana handlowa, zwiększył się zakres inwestycji. Polska w 2008 roku stała się najważniejszym partnerem gospodarczym Niemiec w Europie Środkowej i Wschodniej. Niemcy natomiast od kilku lat są najważniejszym partnerem handlowym Polski zarówno po stronie eksportu, jak i importu. Atrakcyjność Polski w oczach Niemców to nie tylko wzrost obrotów handlowych, napływu niemieckich inwestycji zagranicznych, ale również oparte na przyjaźni relacje społeczne.

2

Schemat tworzenia kompozycji plastycznej wzoru obuwia

81%

Nawara B., Stepniewska A., Karbarz Z.

Przegląd Skórzany

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1986

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tom 41

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nr 04

3

The influence of time and type of solvent on efficiency of the extraction of polyphenols from green tea and antioxidant properties obtained extracts

80%

Druzynska B., Stepniewska A., Wolosiak R.

Acta Scientiarum Polonorum. Technologia Alimentaria

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2007

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tom 06

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nr 1

The aim of the study was to investigate the influence of the type of solvent and time on efficiency of the extraction of polyphenols and antioxidant properties extracts obtained from green tea. Extraction was conducted at room temperature using four solvents: water and 80% ethanol, 80% methanol and 80% acetone (water solutions, v/v) at 15, 30 and 60 minutes. Extracts were analysed for contents of polyphenols and catechins. The antioxidant properties have been determined by two methods: scavenging activity against DPPH and the method with ABTS+. The abilities of extracts to chelate iron ions (II) have been investigated too. On the basis of findings it turned out that both type of solvent and time have a significant influence on extraction of polyphenols from green tea. The best solvent for the extraction of total polyphenols was 80% acetone, whereas for catechins was water. The increase of extraction of polyphenols with prolonged extraction time was observed. All extracts had antioxidant properties against DPPH and ABTS+ and abilities to chelate iron ions (II)

4

Zimowanie nietoperzy Chiroptera w Gdansku

80%

Przesmycka A., Stepniewska A., Jarzembowski T.

Przegląd Przyrodniczy

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1996

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tom 07

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nr 2

92-95

5

Disturbed angiogenic activity in sera from obstructive sleep apnea patients

61%

Chorostowska-Wynimko J., Radomska D., Plywaczewski R., Jonczak L., Stepniewska A., Gorecka D., Skopinska-Rozewska E.

Journal of Physiology and Pharmacology. Supplement

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2005

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tom 56

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nr 4

71-77

It is increasingly recognized that obstructive sleep apnea (OSA) syndrome is a systematic rather than local disorder. There is also growing evidence that apart from the syndrome's major features: intermittent hypoxia and sleep fragmentation, functional activity of the immune system is altered in OSA patients, with several cytokines, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) taking active part in sleep regulation. Little is known about the effects exerted by chronic intermittent hypoxia combined with persistent pro-inflammatory activity of the immune system on the vascular micro milieu in OSA. In this study we attempted to confirm the hypothesized imbalance between pro- and anti-angiogenic factors by evaluating direct and indirect angiogenic activity of OSA patients' sera in the in vivo serum-induced angiogenesis (SIA) and leukocyte-induced (LIA) assays, respectively, in mice. Both tests revealed significantly inhibited angiogenic activity of OSA patients' sera compared with healthy controls (P<0.001). Moreover, differences related to the subject’s weight regarding in the mean number of newly-formed vessels were observed with a significantly greater inhibition in the normal-weighing apneic subjects than in the overweight or obese ones (P<0.01). The angiogenesis inhibition index was positively related to the serum IL-6 level (r=0.35; P<0.05) in the OSA group, but not to TNF-alpha, fasting serum leptin, or OSA syndrome severity as assessed by the AHI index. Our results demonstrate that OSA is accompanied by disturbed serum angiogenic activity, apparently resulting from an imbalance between pro- and anti-angiogenic factors, some of them being produced by the adipose tissue. The disordered angiogenic activity might be related to the pathophysiology of OSA and should be considered an important causative factor for the increased prevalence of cardiovascular diseases in OSA patients.

6

Leptin measurement in urine is a reliable method of monitoring its secretion in patients with obstructive sleep apnea syndrome

61%

Chorostowska-Wynimko J., Plywaczewski R., Jonczak L., Bednarek M., Stepniewska A., Borowska A., Gorecka D.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

7

Inflammatory markers in the exhaled breath condensate of patients with pulmonary sarcoidosis

51%

Rozy A., Czerniawska J., Stepniewska A., Wozbinska B., Goljan A., Puscinska E., Gorecka D., Chorostowska-Wynimko J.

Journal of Physiology and Pharmacology. Supplement

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2006

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tom 57

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nr 4

335-340

Pulmonary sarcoidosis may progress to fibrosis in some patients, so that close monitoring of its activity is essential for recommending clinical strategy. Examination of ariway inflammatory markers in bronchoalveolar lavage (BAL) is one of the methods applied to assess the disease severity. Recently, the expired breath condensate (EBC) has become another source of cytokines and mediators. In sarcoidosis, except for NO and oxidative stress markers, no other mediators have yet been estimated in the exhaled air. In the present study we attempted to answer the question of whether airway inflammatory markers in pulmonary sarcoidosis patients might be assessable in EBC and to what extend these markers might reflect the disease activity in the lungs IL-6, TNF-alpha, PAI-1, and IGF-1 were measured by Elisa method in EBC and BALF samples from 9 patients with newly-diagnosed pulmonary sarcoidosis. TNF-alpha, IGF-1, and PAI-1 levels in EBC and BAL samples were comparable and closely positively correlated [TNF-alpha (r=0.79, P<0.001), IGF-1 (r=0.94, P<0.001), and PAI-1 (r=0.81, P<0.001)]. In contrast, IL-6 concentration in EBC was significantly lower compared with that in BALF, while the correlation between both materials was negative (r=-0.47, P<0.05). An important distinction in IL-6 performance, which might explain this inconsistency, is its tendency to form more complex molecular forms of a higher weight than that of other cytokines. Our study shows that EBC reflects cytokine production in the lung as effectively as BALF, providing that the characteristics of proteins evaluated allow their easy transfer into the exhaled air. Further studies are required before accepting EBC samples as an equivalent to BALF.

Ograniczanie wyników

Polsko-niemieckie stosunki gospodarcze na przykładzie krajów związkowych

Schemat tworzenia kompozycji plastycznej wzoru obuwia

The influence of time and type of solvent on efficiency of the extraction of polyphenols from green tea and antioxidant properties obtained extracts

Zimowanie nietoperzy Chiroptera w Gdansku

Disturbed angiogenic activity in sera from obstructive sleep apnea patients

Leptin measurement in urine is a reliable method of monitoring its secretion in patients with obstructive sleep apnea syndrome

Inflammatory markers in the exhaled breath condensate of patients with pulmonary sarcoidosis