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1

Odporność w zarażeniach helmintami - nowe dane

100%
Dzialo J., Deptula W.
Medycyna Weterynaryjna
|
2011
|
tom 67
|
nr 11
Helminths are multicellular eukaryotic parasites infecting many mammals, including humans. The mammalian immune system is a highly evolved network of cells and molecules that protects macroorganisms from invading pathogens. Immune processes involved in helminth infections are poorly understood. This paper presents the current view on the immune response in helminth infections. We also present new data on this subject, especially the interaction of helminths with PRR receptors and the role of newly discovered immune cells, such as nuocytes, MMPtype² cells, nTh2 cells, Ih2 cells the sources of interleukin 13, which play a very important role in helminth infections.
2

Systematyka wirusów kręgowców - aktualne dane

100%
Dzialo J., Deptula W.
Kosmos
|
2010
|
tom 59
|
nr 3-4
3

Badania filogenetyczne wirusa RHD

100%
Dzialo J., Deptula W.
Medycyna Weterynaryjna
|
2015
|
tom 71
|
nr 01
RHD virus (RHDV), which causes rabbit hemorrhagic disease, is the object of phylogenetic studies. The results of these studies provide valuable information on this pathogen. The purpose of present review is to summarize current knowledge about the phylogenetic position of this virus. The paper discusses the results of previous phylogenetic studies of RHDV, including factors affecting the shape of the phylogeny of this species and the diversity of RHDV strains in different parts of the world. It also presents the results of phylogenetic analysis of RHDV enriched with non-pathogenic and low pathogenic strains of rabbit lagoviruses, as well as phylogenetic analyses performed using modern Bayesian methods. The paper also highlights the unclear situation of Lagovirus taxonomy and shows selected data on the evolution of RHDV, gathered using phylogenetic methods. Finally, the possibility of using rabbit lagoviruses as a model for the study of the evolution of mammalian ssRNA(+) viruses has been shown.
4

Lymphatic tissue of mucosa in the respiratory system

100%
Dzialo J., Deptula W.
Advances in Agricultural Sciences
|
2010
|
tom 13
|
nr 1
5

Important yet little known biological phenomena

81%
Niedzwiedzka-Rystwej P., Dzialo J., Deptula W.
Advances in Agricultural Sciences
|
2010
|
tom 13
|
nr 1
6

Alkohol a zdrowie

81%
Babala O., Dzialo J., Deptula W.
Kosmos
|
2011
|
tom 60
|
nr 1-2
7

Important yet little known biological phenomena

81%
Dzialo J., Poleszczuk J., Deptula W.
Advances in Agricultural Sciences
|
2011
|
tom 14
|
nr 1-2
8

Próba opracowania norm w zakresie wskaźników biało- i czerwonokrwinkowych u krajowych królików mieszańców

71%
Dzialo J., Tokarz-Deptula B., Hukowska-Szematowicz B., Niedzwiedzka-Rystwej P., Deptula W.
Annals of Warsaw University of Life Sciences - SGGW. Animal Science
|
2011
|
tom 48
9

Nowe elementy odporności wrodzonej

71%
Mekal A., Trzeciak-Ryczek A., Tokarz-Deptula B., Dzialo J., Deptula W.
Postępy Biologii Komórki
|
2011
|
tom 38
|
nr 2
10
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Real time PCR detection of rabbit haemorrhagic disease virus in rabbits infected with different European strains of RHDV

71%
Niedzwiedzka-Rystwej P., Hukowska-Szematowicz B., Dzialo J., Tokarz-Deptula B., Deptula W.
Polish Journal of Veterinary Sciences
|
2013
|
tom 16
|
nr 1
The paper concerns the use of a novel, very effective diagnostic method, a real-time PCR for diagnosis of a viral agent causing viral haemorrhagic disease in rabbits – RHDV. Until now, the method was widely used for detecting many different viruses, both DNA, and RNA, but as far as RHDV is concerned, there are not many records of such use. This study aimed at the detection of 17 different strains from different European regions, differing in biological features and mortality. The study confirmed that real-time PCR is an applicable and effective method for diagnosis of RHDV, irrespective of the stains’ features.
11

Peripheral blood lymphocytes B and T and their subpopulations in rabbits infected with rabbit haemorrhagic disease virus (RHDV)

61%
Niedzwiedzka-Rystwej P., Tokarz-Deptula B., Hukowska-Szematowicz B., Dzialo J., Trzeciak-Ryczek A., Deptula W.
Medycyna Weterynaryjna
|
2013
|
tom 69
|
nr 08
The paper describes the assessment of B lymphocytes with CD19+ receptor, as well as T lymphocytes with receptor CD5+, and their subpopulations - T lymphocytes with CD4+, CD8+, CD25+ receptors, in rabbits infected with seven haemagglutinating strains of RHDV from various European countries. The aim of the study was to find out if the newly observed strains carry the same or similar immunological properties as the RHDV strains analysed previously. The study was performed on 70 mixed-breed rabbits divided into 7 groups of infected animals (consisting of 5 animals each), corresponding to the analyzed RHDV strains. For each of seven groups of infected animals a corresponding group of control animals was assigned (consisting of 5 animals each). The dynamics of the chosen lymphocytes and their subpopulations was assessed with the use of flow cytometry and monoclonal antibodies. The results of the study enable the authors to conclude that those 7 strains resemble Czech strains and may be qualified as strains with medium immunogenicity, forming one immunotype.
12

Apoptosis of peripheral blood leukocytes in rabbits infected with different strains of rabbit haemorrhagic disease virus

61%
Niedzwiedzka-Rystwej P., Hukowska-Szematowicz B., Tokarz-Deptula B., Trzeciak-Ryczek A., Dzialo J., Deptula W.
Acta Biochimica Polonica
|
2013
|
tom 60
|
nr 1
 The pathogenicity of RHDV (rabbit haemorrhagic disease virus) is mainly associated with its affinity to blood vessels, with causing disseminated intravascular coagulations (DIC), and with the stimulation of the host immune system. Moreover, there are implications suggesting that apoptosis may be a pivotal process in understanding the basis of viral haemorrhagic disease in rabbits - a serious infectious disease causing mortality to wild and domestic rabbits. The aim of this study is to evaluate, by means of flow cytometry, the dynamics of apoptosis in peripheral blood granulocytes and lymphocytes in rabbits experimentally infected with seven different strains of RHDV and so-called antigenic variants of RHDV denominated as RHDVa, i.e.: Hungarian 24V/89, 1447V/96, 72V/2003; Austrian 01-04, 237/04, V-412 and French 05-01. The results showed that all of the RHDV and RHDVa strains cause an increase in the number of apoptotic cells throughout the infection, which might indicate the need for further analysis of the importance of this process.
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