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IgG avidity: an important serologic marker for the diagnosis of tick-borne encephalitis virus infection

100%

Vilibic-Cavlek T., Barbic L., Stevanovic V., Petrovic G., Mlinaric-Galinovic G.

Polish Journal of Microbiology

2016

tom 65

nr 1

A total of 52 serum samples from patients with symptoms suggestive of tick-borne encephalitis virus (TBEV) infection and positive IgM and/or IgG antibodies were tested for IgG avidity. Acute/recent TBEV infection was confirmed by low/borderline avidity index (AI) in 94.8% IgM positive/IgG positive samples, while in 5.2% high AI was found indicating persisting IgM antibodies. Majority of IgM negative/IgG positive samples (78.6%) showed high AI consistent with past TBEV infection. However, in 21.3% patients without measurable IgM antibodies current/recent infection was confirmed by AI. IgG avidity represents an additional serologic marker that improves diagnosis of TBEV, especially in cases of atypical antibody response.

High prevalence of Bartonella henselae and Bartonella quintana antibodies in Croatian patients presenting with lymphadenopathy

86%

Vilibic-Cavlek T., Karlovic-Martinkovic D., Ljubin-Sternak S., Tabain I., Presic Z., Mlinaric-Galinovic G.

Polish Journal of Microbiology

2012

tom 61

nr 4

Between 2007 and 2010, a total of 268 Croatian patients with lymphadenopathy were tested for IgM/IgG antibodies to Bartonella (B.) henselae and B. quintana. Samples from 44.4% patients showed positive IgG antibodies: 35.8% to B. henselae, 6.7% to B. quintana and 1.9% to both Bartonella species. $ere was no di&erence in seropositivity between males and females (47.4% vs. 41.5%). Seroprevalence was high in all age groups (40.4–60.9%). Patients from urban and rural areas showed a similar seroprevalence rate (44.1% vs. 44.8%). Positive IgM antibodies were found in 28.3% patients varying from 17.5% and 37.5% among age groups. Most cases were reported from August to March.

Ograniczanie wyników

2 Polish Journal of Microbiology

2 Mlinaric-Galinovic G.

2 Vilibic-Cavlek T.

1 Barbic L.

1 Karlovic-Martinkovic D.

1 Ljubin-Sternak S.

1 Petrovic G.

1 Presic Z.

1 Stevanovic V.

1 Tabain I.

1 2016

1 2012

Wyniki wyszukiwania

IgG avidity: an important serologic marker for the diagnosis of tick-borne encephalitis virus infection

High prevalence of Bartonella henselae and Bartonella quintana antibodies in Croatian patients presenting with lymphadenopathy