The aim of the studies was to assess the Panstimase preparation consisting of three proteases from Streptomyces fradiae. It was administered in sows after weaning, during heat, covering, pregnancy and lactation. The experimental group (E) composed of 21 sows was given Panstimase 400 with feed at a dose of 125 g/ton of feed for the first 10 days and then 50 g/ton. The control group included 14 sows. Statistically significant differences were only found on the birthday of piglets in the level of inorganic phosphorus (by 0.2 nmol/1 higher in E group), calcium (by 0.29 nmol/1 lower in E group) and in alanine aminotransferase activity (up to 5.96 IU/1 higher in the control group). On the 28th day of piglets lives, a statistically high significant difference was only found in alanine aminotransferase activity (by 5.81 IU/1 higher in the control group). Statistically significant differences in feed indices were found in the weight of litter on their birthday (by 3.81 kg bigger in group E) and in the number of piglets that died (by 2.11 piglets less in group E). Statistically high significant difference on the 28th day of piglets life was found only in the weight of the litter (by 15.38 kg bigger in E group).
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