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Rozwoj doliny Dolnej Lupawy w poznym plejstocenie

100%

Czerniawska J.

Badania Fizjograficzne nad Polską Zachodnią. Seria A: Geografia Fizyczna

2007

tom 58

21-30

Imaging topography and morphometry of persistent left superior caval vein and its variations, detected on cardiac implantable electronic device implantation

45%

Steckiewicz R., Swieton E. B., Czerniawska J., Scislo P., Stolarz P.

Folia Morphologica

2017

tom 76

nr 1

Background: Persistent left superior caval vein (PLSCV) is a rare, anatomically diverse developmental anomaly of systemic veins. Clinically asymptomatic PLSCVs are detected incidentally during medical procedures that utilise systemic veins, such as cardiac implantable electronic device (CIED) placement, and whose successful completion depends on favourable morphometric parameters of these vessels. The aim of this paper was to present topography and morphometry of PLSCV variations encountered during CIED implantation procedures. Materials and methods: We analysed a group of 5,010 patients for detection of PLSCV during de-novo CIED implantation procedures with transvenous lead placement in the years 2003–2015. PLSCVs were detected intraprocedurally based on venographic images illustrating the venous anomaly and its morphometric parameters, and were subsequently confirmed via postoperative diagnostics. Results: PLSCVs were detected in 10 patients (mean age 66.0 ± 14.0 years; 5 females and 5 males), who constituted 0.2% of the analysed group. There were 6 cases of double superior vena cava (DSVC), 3 of which had a brachiocephalic vein (BCV) connection and did not have BCV bridging. Four patients with a PLSCV had right superior vena cava agenesis; this very rare variation is known as ‘single PLSCV’. All of the detected PLSCV variations drained into the right atrium via the coronary sinus. Conclusions: Our data from a period of 13 years illustrate how rare the PLSCV-type venous anomaly is. The three distinct anatomical PLSCV types showed inter-individual morphometric variations. Due to asymptomatic nature of this anomaly, all cases were detected incidentally, during CIED implantation procedures. (Folia Morphol 2017; 76, 1: 58–65)

Inflammatory markers in the exhaled breath condensate of patients with pulmonary sarcoidosis

33%

Rozy A., Czerniawska J., Stepniewska A., Wozbinska B., Goljan A., Puscinska E., Gorecka D., Chorostowska-Wynimko J.

Journal of Physiology and Pharmacology. Supplement

2006

tom 57

nr 4

335-340

Pulmonary sarcoidosis may progress to fibrosis in some patients, so that close monitoring of its activity is essential for recommending clinical strategy. Examination of ariway inflammatory markers in bronchoalveolar lavage (BAL) is one of the methods applied to assess the disease severity. Recently, the expired breath condensate (EBC) has become another source of cytokines and mediators. In sarcoidosis, except for NO and oxidative stress markers, no other mediators have yet been estimated in the exhaled air. In the present study we attempted to answer the question of whether airway inflammatory markers in pulmonary sarcoidosis patients might be assessable in EBC and to what extend these markers might reflect the disease activity in the lungs IL-6, TNF-alpha, PAI-1, and IGF-1 were measured by Elisa method in EBC and BALF samples from 9 patients with newly-diagnosed pulmonary sarcoidosis. TNF-alpha, IGF-1, and PAI-1 levels in EBC and BAL samples were comparable and closely positively correlated [TNF-alpha (r=0.79, P<0.001), IGF-1 (r=0.94, P<0.001), and PAI-1 (r=0.81, P<0.001)]. In contrast, IL-6 concentration in EBC was significantly lower compared with that in BALF, while the correlation between both materials was negative (r=-0.47, P<0.05). An important distinction in IL-6 performance, which might explain this inconsistency, is its tendency to form more complex molecular forms of a higher weight than that of other cytokines. Our study shows that EBC reflects cytokine production in the lung as effectively as BALF, providing that the characteristics of proteins evaluated allow their easy transfer into the exhaled air. Further studies are required before accepting EBC samples as an equivalent to BALF.

Ograniczanie wyników

1 Badania Fizjograficzne nad Polską Zachodnią. Seria A: Geografia Fizyczna

1 Folia Morphologica

1 Journal of Physiology and Pharmacology. Supplement

3 Czerniawska J.

1 Chorostowska-Wynimko J.

1 Goljan A.

1 Gorecka D.

1 Puscinska E.

1 Rozy A.

1 Scislo P.

1 Steckiewicz R.

1 Stepniewska A.

1 Stolarz P.

1 Swieton E. B.

1 Wozbinska B.

1 2017

1 2007

1 2006

Wyniki wyszukiwania

Rozwoj doliny Dolnej Lupawy w poznym plejstocenie

Imaging topography and morphometry of persistent left superior caval vein and its variations, detected on cardiac implantable electronic device implantation

Inflammatory markers in the exhaled breath condensate of patients with pulmonary sarcoidosis