The aim of the work was to prepare an inactivated vaccine against ovine campylobacteriosis and evaluate its immunogenic properties. For the vaccine production there was used 4 strains of Campylobacter fetus subsp. fetus, serotype B, isolated from the fetus of an aborted sheep. The prepared vaccine was first tested on laboratory animals and later administered intramuscularly at a dose of 4 ml (0.38 X 10¹¹ bacteria per 1 ml) to 61 sheep being in the second month of pregnancy. The level of neutralizing antibodies was tested 6 times. It was found that vaccination elicited a high level of specific antibodies whose titers were rising especially between 4 and 6 weeks after vaccination. A high level of antibodies persisted up to the end of pregnancy.
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