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Platelets and the clinical course of Crohn's disease

100%

Padysz M., Stec-Michalska K., Banasik J., Gasiorowska A.

Health Problems of Civilization

2018

tom 12

nr 4

Background. Crohn’s disease (CD) is a chronic, autoimmune, inflammatory bowel disease (IBD) characterised by periods of exacerbations and remissions. Autoimmune disorders caused by undetermined factors lead to inflammation in the intestinal mucosa. Presently, there is a growing interest in the role of platelets in the assessment of inflammatory lesions in CD. Accordingly, the aim of this study was to answer the question of whether routinely measured platelet indices: concentration of platelets (PLT), the mean platelet volume (MPV), plateletcrit (PCT) could become biomarkers for monitoring the course of CD. Material and methods. In the study programme, there were enrolled 100 patients with a diagnosed CD with a different clinical course, disease location and heterogeneous therapy. In all patients, there were collected blood and stool samples for the assessment of CRP, blood count and fecal calprotectin evaluation. The clinical state of each patient was classified using the Harvey-Bradshaw index. Results. The study showed a positive, statistically significant correlation between fecal calprotectin, CRP, WBC, the Harvey-Bradshaw index and the number of platelets and PCT. Furthermore, the analysis showed a statistically significant negative correlation between MPV and the number of WBC, CRP and fecal calprotectin. Conclusions. Our study showed that platelet indices are a valuable, non-invasive and widely accessible method to assess mucosal healing and the clinical status of the patient.

Sleep disturbance and disease activity in adult patients with inflammatory bowel diseases

76%

Sobolewska-Wlodarczyk A., Wlodarczyk M., Banasik J., Gasiorowska A., Wisniewska-Jarosinska M., Fichna J.

Journal of Physiology and Pharmacology

2018

tom 69

nr 3

Wieloletnia zmienność odpływu z małej zlewni rzecznej w regionie Puszczy Kozienickiej

76%

Banasik K., Hejduk L., Hejduk A., Kaznowska E., Banasik J., Byczkowski A.

Sylwan

2013

tom 157

nr 08

Kozienice Forest (central Poland) belongs to very valuable areas from touristic and ecological point of view. Water resources are important factor of further development of this region. Analysis of 49−year (1963−2011) annual and seasonal rainfall and runoff characteristics from a small (82 km2) catchment of Zagożdżonka River, with forestation ratio of 0.40, indicated a statistically significant decrease for six of the nine considered parameters. Mann−Kendall test was used for trend analysis. Decreased trend was indicated for annual runoff and annual runoff coefficient, median discharge, summer half−year runoff coefficient, median summer discharge and for low mean 30−day discharge. No trend was detected for annual precipitation and summer half year precipitation nor for summer half year runoff.

Ograniczanie wyników

1 Health Problems of Civilization

1 Journal of Physiology and Pharmacology

1 Sylwan

3 Banasik J.

2 Gasiorowska A.

1 Banasik K.

1 Byczkowski A.

1 Fichna J.

1 Hejduk A.

1 Hejduk L.

1 Kaznowska E.

1 Padysz M.

1 Sobolewska-Wlodarczyk A.

1 Stec-Michalska K.

1 Wisniewska-Jarosinska M.

1 Wlodarczyk M.

2 2018

1 2013

Wyniki wyszukiwania

Platelets and the clinical course of Crohn's disease

Sleep disturbance and disease activity in adult patients with inflammatory bowel diseases

Wieloletnia zmienność odpływu z małej zlewni rzecznej w regionie Puszczy Kozienickiej