Tomato plants are often infected by viral pathogens belonging to different families. As a result of virus‐host interaction numerous mechanisms in plants are induced, such as appearance of additional structures and inclusions in the cytoplasm, or changes in a structure of organelles. For this reason, the analyses of cytological changes within the leaf of tomato, induced by Tomato torrado virus (ToTV) and Pepino mosaic virus (PepMV) were performed. The presence of viral particles in various compartments of individual cell types, arranged specifically for each type of virus was observed. Moreover, in both cases we observed changes in activity of the organelles responsible for the metabolic processes (chloroplasts, mitochondria) and thickened of the cell wall.