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1

Rola bialek STAT w chorobach zapalnych i karcynogenezie jelita grubego

100%
Wincewicz A., Sulkowska M., Koda M., Musiatowicz B., Sulkowski S.
Postępy Biologii Komórki
|
2005
|
tom 32
|
nr 1
23-36
2

Expression of leptin and its receptor in female breast cancer in relation with selected apoptotic markers

100%
Koda M., Sulkowska M., Kanczuga-Koda L., Jarzabek K., Sulkowski S.
Folia Histochemica et Cytobiologica. Supplement
|
2007
|
tom 45
|
nr 1
187-191
3

Increased expression of gap junction protein - connexin 32 in lymph node metastases of human ductal breast cancer

100%
Kanczuga-Koda L., Sulkowska M., Koda M., Rutkowski R., Sulkowski S.
Folia Histochemica et Cytobiologica. Supplement
|
2007
|
tom 45
|
nr 1
175-180
4
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Antiplatelet action of losartan involves TXA2 receptor antagonism but not TXA2 synthase inhibition

100%
Chlopicki S., Koda M., Chabielska E., Buczko W., Gryglewski R. J.
Journal of Physiology and Pharmacology
|
2000
|
tom 51
|
nr 4,1
5

Green tea as an antioxidant which protects against alcohol induced injury in rats - a histopathological examination

100%
Baltaziak M., Skrzydlewska E., Sulik A., Famulski W., Koda M.
Folia Morphologica
|
2004
|
tom 63
|
nr 1
Our study with animal models was designed to test the hypothesis that green tea protects against chronic (over 4 weeks) alcohol induced liver injury in rats. The research was conducted on Wistar male rats divided into 4 research groups: I — received the Libera-De Carli control diet (L-DC), II — received (L-DC) and green tea, III — received (L-DC) and ethanol and IV — received (L-DC), green tea and ethanol. When comparing groups I and II we saw less intensive steatosis in group II than in group I, which can suggest that green tea may affect the accumulation of fat in the hepatocytes and protect them against steatosis and disruption. In III, the ethanol group, the steatosis of the liver increased considerably and the green tea which was given with ethanol in group IV did not halt this, as in group IV we also observed intensive steatosis in the liver. From this data we conclude that green tea has an important, although not fully understood role in preventing liver injury.
6

Expression of connexins 26, 32 and 43 in the human colon - an immunohistochemical study

100%
Kanczuga-Koda L., Sulkowski S., Koda M., Sobaniec-Lotowska M., Sulkowska M.
Folia Histochemica et Cytobiologica
|
2004
|
tom 42
|
nr 4
7

STAT3 and hypoxia induced proteins – HIF-1alpha, EPO and EPOR in relation with Bax and Bcl-xL in nodal metastases of ductal breast cancers

86%
Wincewicz A., Koda M., Sulkowska M., Kanczuga-Koda L., Wincewicz D., Sulkowski S.
Folia Histochemica et Cytobiologica
|
2009
|
tom 47
|
nr 3
8

Expression of estrogen receptors alpha and beta in term human myometrium

86%
Laudanski P., Redzko S., Przepiesc J., Koda M., Wolczynski S., Sulkowski S., Urban J.
Reproductive Biology
|
2004
|
tom 04
|
nr 3
9

Expression of connexin 26 in endometrial adenocarcinoma - analysis of correlations with some anatomoclinical features

86%
Lesniewicz T., Kanczuga-Koda L., Baltaziak M., Sulkowska M., Rutkowski R., Koda M., Sulkowski S.
Folia Histochemica et Cytobiologica
|
2008
|
tom 46
|
nr 2
171-176
10

An evaluation of Ki-67 and PCNA expression in conjunctival and eyelid tumours

86%
Reszec J., Kanczuga-Koda L., Sulkowska M., Koda M., Cylwik J., Barwijuk-Machala M., Sulkowski S.
Folia Morphologica
|
2004
|
tom 63
|
nr 1
The aim of our study was an evaluation of the expression of cell proliferation markers (PCNA and Ki-67) in conjunctival and eyelid papillomas and squamous and basal cell cancers. A series of 9 cases of squamous cell cancer (SCC), 15 cases of basal cell cancer (BCC) and 43 cases of squamous cell papilloma (SCP) were assessed using the immunohistochemical method with monoclonal antibodies. PCNA overexpression was observed in 100% of SCP, in 88.8% of SCC and in 100% of BCC cases. Ki-67 overexpression was seen in 32.5% of cases of SCP, in 22.2% of SCC and in 66.6% of BCC. The results showed that an evaluation of Ki-67 expression is the most valuable cell proliferation marker.
11

STAT3, HIF-1alpha, EPO and EPOR - signaling proteins in human primary ductal breast cancers

86%
Wincewicz A., Sulkowska M., Koda M., Lesniewicz T., Kanczuga-Koda L., Sulkowski S.
Folia Histochemica et Cytobiologica
|
2007
|
tom 45
|
nr 2
12

Transplantation of human bone marrow stromal cell-derived neuroregenrative cells promotes functional recovery after spinal cord injury in mice

72%
Mannoji C., Koda M., Kamiya K., Dezawa M., Hashimoto M., Furuya T., Okawa A., Takahashi K., Yamazaki M.
Acta Neurobiologiae Experimentalis
|
2014
|
tom 74
|
nr 4
Transplantation of bone marrow stromal cells (BMSCs) for spinal cord injury (SCI) has been shown to improve functional outcome. BMSCs can be easily obtained from bone marrow aspirate and have fewer problems in the clinical application for human SCI from the ethical and legal points of view. Recently, we produced cells with neural stem and/or progenitor cell property and neural regeneration supporting capacity from human bone marrow stromal cells (human bone marrow stromal cell-derived neuroregenerative cells: hBMSC-NRs). The aim of the present study was to clarify the effectiveness of transplantation of hBMSC-NRs to injured spinal cord of severe combined immunodeficiency (NOD/SCID) mice. Neurite outgrowth assay of PC-12 cells was performed. One week after a T9-level contusion SCI, hBMSCs or hBMSC-NRs were transplanted into the spinal cord. After the transplantation, functional and histological examinations were performed. Conditioned media of hBMSC-NRs significantly promoted the neurite outgrowth of PC-12 cells in vitro. Transplanted hBMSC-NRs survived in the injured spinal cord 8 weeks after SCI. Immunohistochemistry revealed that the density of serotonin-positive fibers of the transplanted group was significantly higher than that of the control group at the epicenter and caudal segment to the injured site. The recovery of hind limb function of the hBMSC-NRs group was significantly better than that of the control group. In conclusion, hBMSC-NRs can be one of the realistic candidates for cell transplantation therapy for human SCI.
13

The relationships between hypoxia-dependent markers: HIF-1alpha, EPO and EPOR in colorectal cancer

72%
Baltaziak M., Wincewicz A., Kanczuga-Koda L., Lotowska J. M., Koda M., Sulkowska U., Baltaziak M., Podbielska M., Sobaniec-Lotowska M. E., Sulkowski S.
Folia Histochemica et Cytobiologica
|
2013
|
tom 51
|
nr 4
14

Expression of the apoptotic markers in normal breast epithelium, benign mammary dysplasia and in breast cancer

72%
Koda M., Kanczuga-Koda L., Reszec J., Sulkowska M., Famulski W., Baltaziak M., Kisielewski W., Sulkowski S.
Folia Morphologica
|
2004
|
tom 63
|
nr 3
Apoptosis and proliferation are processes associated with the development and progression of breast cancer. The sensitivity of tumour cells to the induction of apoptosis depends on the balance between pro- and anti-apoptotic proteins. The expression of Bak and Bcl-2 was examined using an immunohistochemical method in 71 primary breast cancers. Furthermore, Bcl-2 and Bak were assessed in the normal mammary gland as well as in benign mammary dysplasia adjacent to breast cancer. Positive immunostaining for Bcl-2 was observed in 77.8% of cases of normal breast epithelium (NBE), 93% of benign dysplasia without intraductal proliferation (BBD) as well as in 94% of intraductal proliferative lesions of the breast (BIPL). Expression of Bak was detected in 39% of cases of NBE, 45% of BBD and in 67% of BIPL. In breast cancer Bcl-2 and Bak expression was found in 83% and 70% of the cases studied, respectively. Increased Bcl-2 expression in primary tumours significantly correlated with favourable prognostic factors, namely pT1, G2 and lack of metastases to the regional lymph nodes (p < 0.01, p < 0.03, p < 0.02, respectively). There were no relationships between Bak and the clinicopathological features studied, but our results indicate changes in the expression of Bak during breast cancer development and progression. It would appear to be important to assess and compare pro- and anti-apoptotic proteins between normal mammary gland, benign mammary dysplasia and the primary tumours of breast cancer. This knowledge should be helpful in understanding breast cancer development and progression.
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