Wyniki wyszukiwania

1

Wscieklizna i jej profilaktyka u ludzi

100%

Ostrowska J. D., Hermanowska-Szpakowicz T.

Medycyna Weterynaryjna

|

1997

|

tom 53

|

nr 03

144-147

2

Interleukina 6 w hodowlach neurofilow i komorek jednojadrzastych oraz surowicy krwi pacjentow w przebiegu boreliozy z Lyme

81%

Jablonska E., Puzewska W., Marcinczyk M., Hermanowska-Szpakowicz T.

Medycyna Doświadczalna i Mikrobiologia

|

2003

|

tom 55

|

nr 1

81-87

Oceniano zdolność neutrofílów i komórek jednojądrzastych do uwalniania interleukiny 6 (IL-6) w porównaniu z jej poziomem w surowicy krwi osób z boreliozą z Lyme i osób zdrowych. Uzyskane wyniki wskazują, że zarówno neurofile jak i komórki jednojądrzaste mogą wpływać na reakcje kontrolowane przez IL-6 u badanych pacjentów.

3

Wplyw rekombinowanej ludzkiej interleukiny 15 na ekspresje receptora Toll - podobnego typu 2 oraz apoptoze neutrofilow u pacjentow z borelioza z Lyme

81%

Marcinczyk M., Jablonska E., Puzewska W., Hermanowska-Szpakowicz T.

Medycyna Doświadczalna i Mikrobiologia

|

2005

|

tom 57

|

nr 1

85-91

Oceniano wpływ rekombinowanej ludzkiej interleukiny 15 (rhIL-15) na ekspresję receptora Toll - podobnego typu 2 (TLR2) i apoptozę neutrofilów u pacjentów z boreliozą z Lyme. Ekspresja TLR2 w neutrofilach byla określana metodą western biot, apoptoza - metodą immunofluorescencyjną. Stwierdzono, że rhIL-15 wykazuje istotny wpływ na TLR2 oraz proces apop- tozy neutrofilów, co sugeruje jej potencjalną przydatność w efektywnej modulacji odpowiedzi komórkowej nieswoistej przeciw krętkom Borrelia burgdorferi.

4

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Czas utrzymywania sie dodatnich wynikow badan serologicznych u osob operowanych z rozpoznaniem bablowicy watroby - obserwacje wlasne

71%

Kondrusik M., Pancewicz S. A., Zajkowska J. M., Hermanowska-Szpakowicz T., Snarska J.

Wiadomości Parazytologiczne

|

1999

|

tom 45

|

nr 3

387-389

The purpose of this Work was to analyse results of serologie examinations and complaints reported by patients who were operated on echinococcal liver cysts. The analysis was conducted on patients who were qualified to surgical removal of echionococcal liver cysts. Persons who were analysed answered the questionaires and 11 of them send sera for serologie examination. The questionaires consisted of questions about time since operation, complaints before and after operation abdomen pains, distensions, vomits, exanthema, weakness, headaches). Results showed that patient were from 1 to 6 years after operation. Among 11 who send sera 18% results were negative (2 and 6 years after operation) and 82% was positive. Analysis of 15 questionnaires showed that majority of patients still had the complaints that were present before operation.

5

The time of maintainance of positive serologic results among patients operated on echinococcal liver cysts

71%

Kondrusik M., Pancewicz S. A., Zajkowska J. M., Hermanowska-Szpakowicz T., Snarska J.

Wiadomości Parazytologiczne

|

1998

|

tom 44

|

nr 3

6

Bakteriobojcze wlasciwosci granulocytow obojetnochlonnych [PMN] krwi obwodowej u chorych z borelioza z Lyme

61%

Izycka A., Jablonska E., Zajkowska J., Hermanowska-Szpakowicz T., Izycki T., Piecuch J., Pancewicz S.

Medycyna Doświadczalna i Mikrobiologia

|

2000

|

tom 52

|

nr 2

165-171

Oceniano aktywność fagocytarną związaną z wybuchem tlenowym granulocytów obojętnochłonnych u chorych z boreliozą z Lyme. Wykazano spadek wartości badanych parametrów w ostrej fazie choroby oraz ich normalizację w badaniu odległym, wykonanym po sześciu miesiącach od zakończenia leczenia. Poprawa badanych funkcji neutrofilów w badaniach odległych sugeruje, że obserwowane zmiany mają charakter nabyty, uwarunkowany obecnością krętka Borrelia burgdorferi.

7

Wystepowanie przeciwcial dla antygenow Francisella tularensis u pracownikow lesnych w wybranych regionach Polski

61%

Rastawicki W., Kurowska J., Hermanowska-Szpakowicz T., Pancewicz S. A., Kondrusik M., Jagielski M.

Medycyna Doświadczalna i Mikrobiologia

|

2006

|

tom 58

|

nr 3

207-215

Oceniono częstość występowania przeciwciał dla F. tularensis u pracowników leśnych w wybranych regionach Polski. W żadnej z 480 badanych próbek surowicy uzyskanych od pracowników leśnych nic stwierdzono podwyższonego poziomu swoistych przeciwciał odczynem aglutynacji probówkowej. Odczynem ELISA obecność przeciwciał klasy IgA w mianie diagnostycznie znamiennym wykryto u 4,6%, przeciwciał klasy IgG u 3,8% i przeciwciał klasy IgM u 2,7% pracowników leśnych.

8

Detectibility of antibodies against Borrelia burgdorferi among forest workers in North-Eastern Poland

61%

Pancewicz S. A., Kondrusik M., Zajkowska J. M., Snarska-Furla I., Swierzbinska R., Hermanowska-Szpakowicz T.

Wiadomości Parazytologiczne

|

1998

|

tom 44

|

nr 3

9

Prevalence of DNA and antibodies to Borrelia burgdorferi sensu lato in dogs suspected of borreliosis

51%

Skotarczak B., Wodecka B., Rymaszewska A., Sawczuk M., Maciejewska A., Adamska M., Hermanowska-Szpakowicz T., Swierzbinska R.

Annals of Agricultural and Environmental Medicine

|

2005

|

tom 12

|

nr 2

199-205

The aim of the paper was an attempt to correlate clinical signs with the presence of DNA of Borrelia burgdorferi (sensu lato) s.l. and the antibodies against B. burgdorferi s.l. in the blood of dogs. Among the animals studied there were 62 dogs delivered to the Veterinary Clinic in Szczecin and 30 from the Municipal Animal Shelter in Szczecin with varied clinical signs of borreliosis. In all cases the owners admitted frequent contacts of their dogs with ticks, both in the past, as well as shortly before the onset of sickness. We used two methods: PCR for detecting DNA of B. burgdorferi s.l. and ELISA test for detecting antibodies against the spirochete. Lameness, the principal symptom of canine borreliosis was the most frequent symptom of the group of 31 PCR-positive animals. The other most common symptoms in PCR-positive dogs were fever, swelling of joints and loss of body weight. DNA of B. burgdorferi s.l. was most frequently detected in the blood of dogs of the group 2-5 years old (13/54.1%). ELISA tests specific for IgG antibodies were positive in 37 of 92 sera (40.2%) taken from examined dogs. Lameness was observed in 15 of 37 IgG-seropositive dogs and in 25 of 55 seronegative animals. In 54% of dogs with the antibodies, swelling of instep- and wrist joints was observed compared to only 24.4% in seronegative dogs. An attempt to correlate the PCR results with the results of tests detecting antibodies against B. burgdorferi s.l. revealed that fewer than half (45.1%) of the dogs with presence of DNA of the spirochete, developed an immune response. Therefore the transfer of B. burgdorferi s.l. form, the primary lesion to the target tissues, is possible in dogs which did not develop immune response or develop an insufficient response. Among 92 borreliosis-suspected dogs 54 (over 58%) were diagnosed positively using laboratory methods. In most cases there was a correlation between clinical symptoms of borreliosis and presence of DNA B. burgdorferi, thus PCR may contribute to improving to a large extent diagnostic of canine Lyme disease.

10

Molecular and serological diagnosis of Borrellia burgdorferi infection among patients with diagnosed erythema migrans

51%

Kondrusik M., Grygorczuk S., Skotarczak B., Wodecka B., Rymaszewska A., Pancewicz S., Zajkowska J., Swierzbinska R., Hermanowska-Szpakowicz T.

Annals of Agricultural and Environmental Medicine

|

2007

|

tom 14

|

nr 2

The aim of the study was to assess the frequency of Borrelia burgdorferi DNA detection in the blood and urine of patients diagnosed with erythema migrans, and compare the results of PCR-based methods with ELISA methodology. The latter was used to detect serum antibodies against Borrelia burgdorferi of the IgM and IgG classes, before and after antibiotic therapy. The study included 86 patients hospitalized in the Department of Infectious Diseases and Neuroinfections in the Medical Academy in Białystok, diagnosed with the erythema migrans phase of Lyme borreliosis. Examinations were carried out twice: the fi rst at the moment of diagnosis (Trial 1), the second after 4 weeks of antibiotic therapy. The study showed that antibiotic therapy in the early phase of borreliosis does not decrease the sensitivity of PCR and that after 4 weeks of therapy (Trial 2), spirochete DNA is still detectable in most patients (45/86). There was no correlation between detectability of spirochete DNA and the presence of antibodies against B. burgdorferi s.l. (assessed by ELISA) during the course of erythema migrans. The largest percentage of positive results in the detection of B. burgdorferi s.l. DNA was observed in patients who simultaneously possessed IgM and IgG antibodies against B. burgdorferi, while the lowest percentage of PCR positive results was among patients with only IgM antibodies.

11

Detecting DNAs of Anaplasma phagocytophilum and Babesia in the blood of patients suspected of Lyme disease

51%

Hermanowska-Szpakowicz T., Skotarczak B., Kondrusik M., Rymaszewska A., Sawczuk M., Maciejewska A., Adamska M., Pancewicz S., Zajkowska J.

Annals of Agricultural and Environmental Medicine

|

2004

|

tom 11

|

nr 2

Co-occurrence of granulocytic anaplasmosis, borreliosis and babesiosis in humans is a result of common vectors for the respective pathogens of these diseases, most commonly ticks from the genus Ixodes. Studies on ticks in Europe and also in Poland have shown that several pathogens may co-occur in individuals of I. ricnus. A total of 96 hospitalised patients infected or suspected of being infected with borreliosis were screened for A. phagocytophilum and Babesia sp. DNA. Positive results of PCRs for A. phagocytophilum DNA were obtained for 10 patients, 8 of whom were diagnosed with borreliosis earlier, and 4 of whom were diagnosed with tick-borne encephalitis (on the basis of serological studies of serum and cerebrospinal fluid). None of the 10 patients had clinical or biochemical markers of anaplasmosis, corroborating the existence of asymptomatic anaplasmosis or self-limiting course. in Europe. Similarly, Babesia DNA was not found in the blood of any of the patients. The results of the studies show that in diagnosing tick-borne diseases, clinical examinations should consider infection by two or even three tick-borne pathogens.

Ograniczanie wyników

Wscieklizna i jej profilaktyka u ludzi

Interleukina 6 w hodowlach neurofilow i komorek jednojadrzastych oraz surowicy krwi pacjentow w przebiegu boreliozy z Lyme

Wplyw rekombinowanej ludzkiej interleukiny 15 na ekspresje receptora Toll - podobnego typu 2 oraz apoptoze neutrofilow u pacjentow z borelioza z Lyme

Czas utrzymywania sie dodatnich wynikow badan serologicznych u osob operowanych z rozpoznaniem bablowicy watroby - obserwacje wlasne

The time of maintainance of positive serologic results among patients operated on echinococcal liver cysts

Bakteriobojcze wlasciwosci granulocytow obojetnochlonnych [PMN] krwi obwodowej u chorych z borelioza z Lyme

Wystepowanie przeciwcial dla antygenow Francisella tularensis u pracownikow lesnych w wybranych regionach Polski

Detectibility of antibodies against Borrelia burgdorferi among forest workers in North-Eastern Poland

Prevalence of DNA and antibodies to Borrelia burgdorferi sensu lato in dogs suspected of borreliosis

Molecular and serological diagnosis of Borrellia burgdorferi infection among patients with diagnosed erythema migrans

Detecting DNAs of Anaplasma phagocytophilum and Babesia in the blood of patients suspected of Lyme disease