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1

Antimicrobial susceptibility of Staphylococcus spp. isolated from dogs with pyoderma

100%
Siugzdaite J., Zamokas G., Grigonis A., Macijauskas V., Lasys V.
Medycyna Weterynaryjna
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2008
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tom 64
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nr 08
The aim of this study was to evaluate antimicrobic resistance in canine staphylococci to the major classes of antimicrobials used in veterinary dermatology. The data was collected in 2002-2006 in the Dr L. Kriauceliunas small animal clinic of the Lithuanian Veterinary Academy. Clinical evaluation of 163 dogs was performed together with microscopical, mycological and bacteriological examinations. The clinical evaluation included the age of the dog, breed, sex, hair structure and season of the year. The authors found out that during the 5 year period males got the disease more often than females (52.98% versus 42.02%) and dogs at the ages of 1-5 years were the most common patients (43.9%). Bacterial skin diseases were more common in short-haired dogs (61.81%, p < 0.05). Long-haired dogs were more likely to be affected by bacterial skin diseases in the cold season (p < 0.05). Bacteriological examination revealed that the most common cause of bacterial skin infections was Staphylococcus intermedius (71.76%, p < 0.05) and Staphylococcus aureus (23.68%, p < 0.05). Mixed cultures (Staphylococcus spp., Streptococcus spp., Pseudomonas spp. and Escherichia coli) were found to be the cause of 4.56% (p < 0.05) of all bacterial skin diseases. S. intermedius and S. aureus strains exhibited the best sensitivity to ciprofloxacin, amikacin, methicillin (100%) and to cephadroxil (respectively 91.75% and 100%). S. intermedius strains were most resistant to sulphanilamides/trimethoprim (82.28%), S. aureus - to amoxicillin (86.0%).
2
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Efficacy of topical therapy with newly developed terbinafine and econazole formulations in the treatment of dermatophytosis in cats

100%
Iwaskiene M., Matusevicius A. P., Grigonis A., Zamokas G., Babickaite L.
Polish Journal of Veterinary Sciences
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2016
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tom 19
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nr 3
In the field of veterinary dermatology dermatophytosis is one of the most frequently occurring infectious diseases, therefore its treatment should be effective, convenient, safe and inexpensive. The aim of this study was to evaluate the efficacy of newly developed topical formulations in the treatment of cats with dermatophytosis. Evaluation of clinical efficacy and safety of terbinafine and econazole formulations administered topically twice a day was performed in 40 cats. Cats, suffering from the most widely spread Microsporum canis-induced dermatophytosis and treated with terbinafine hydrochloride 1% cream, recovered within 20.3±0.88 days; whereas when treated with econazole nitrate 1% cream, they recovered within 28.4±1.14 days. A positive therapeutic effect was yielded by combined treatment with local application of creams and whole coat spray with enilconazole 0.2% emulsion „Imaverol”. Most cats treated with econazole cream revealed redness and irritation of the skin at the site of application. This study demonstrates that terbinafine tended to have superior clinical efficacy (p<0.001) in the treatment of dermatophytosis in cats compared to the azole tested.
3
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Therapeutic activity of chlorhexidine-poloxamer antiseptic gel on wound healing in rats: a preclinical study

86%
Babickaite L., Grigonis A., Ramanauskiene K., Matusevicius A. P., Zamokas G., Daunoras G., Ivaskiene M.
Polish Journal of Veterinary Sciences
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2018
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tom 21
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nr 1
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