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Water samples were collected from the drinking water source of 21 urban areas from the lower Yangtze River at Jiangsu province and various surface drinking water sources of Jiangsu, Zhejiang, and Shandong provinces of China. They were tested for 25 VOCs and 38 SVOCs using purge and trap (P&T) and gas chromatography – mass spectrometry (GC-MS). The results show there were 19 VOCs and 10 SVOCs detected several times in at least one drinking water source. One hundred and twenty-six samples from 21 sampling sites were found to have organic compound pollutants in the range of less than MDL to 27.79 μg/L, including volatile chlorinated hydrocarbons, BTEX, chlorinated benzenes, phenols, nitrobenzene, phthalate esters, pesticides, et al. – in total 21 types of organic compounds considered to be priority water pollutants by the Chinese Department of Water Resources. However, the concentrations of VOCs and SVOCs in samples from the lower Yangtze River were markedly different from those in surface drinking water sources in Jiangsu, Zhejiang, and Shandong provinces. PAEs were detected in all water samples, but PCP and Rogor were only detected in samples from the lower Yangtze River. It should be noted that the majority of water samples with detected atrazine were from Jiangsu and Shandong provinces. The main SVOCs detected in the Yangtze River included PCP, Rogor, nitrobenzene, and PAEs. More pollutants were detected in the surface waters of Jiangsu than those of Zhejiang and Shandong. Among the surface water sources in Zhejiang, there were more species of VOCs and SVOCs in the Shanhusha Reservoir than the other reservoirs, which may have resulted from pollutants in Qiantang River water. Though the types and levels of water pollutants varied from one region to another in Jiangsu, Zhejiang, and Shandong provinces, our report added new evidence that the Yangtze River and other urban surface water sources have been universally polluted, and we recommend that all potential sources should be traced and mediated. In addition, because these persistent pollutants may be a health risk if transferred to drinking water, drinking water quality must be controlled specifically for certain VOC's and installation of a monitoring program/quality control for drinking water resources is needed.
Wetland protection, floral and faunal resource management, and habitat migration are all concerns for the ecological risk of wetland landscapes. Indices of landscape-scale ecological risks have the potential to influence changes in landscape patterns, the conditions of endangered plants and animals, and influences from nature and humans. Semi-variation function and gravity center models were used to quantify risk area changes. The changes of landscape ecological risk were analyzed for Bayanbulak Wetland from 2000 to 2010. In addition to landscape and species distribution data, GIS technology and remote sensing were used in this study. Results show that landscape structure changed over the 10-year period, with high-cover grassland area decreasing the most. Landscape pattern index types also changed for the study area. The number of landscapetype patches to low-cover grassland decreased, the landscape fragmentation index of dry land and high-cover grassland was reduced, and the interference degree of middle-cover grassland increased over the study period. The index of landscape ecological risk decreased from 2000 to 2010, with the spatial structure changing from a single center concentration to a multi-center distribution. All varying ecological risk regions of gravity centers moved from the northeast to the southwest. The gravity migration of the Level 2 region moved the furthest. Additionally, evidence suggests that various threatening factors reduce the ecological function and systems of wetlands. These include climate change, biological invasion, human activities, and water pollution. This paper assesses the heritage site landscape ecological risk and calculates the gravity center change of the region, which can be formulated to enrich and develop the research of small- and medium-sized wetlands in cold, semi-arid climates.
At present, overseas and domestic eco-security early warning research is in the exploratory stage. This paper uses Kizilsu Kirghiz Autonomous Prefecture as the research object and constructs an evaluation index system based on the pressure-state-response (P-S-R) conceptual model. This study analyzes eco-security early warning in the study area using the granger causality test model, the entropy weight method, and the matter-element model, and analyzes the present eco-security situation and future development trends in the study area. The author hopes that this study can further enrich eco-security early warning research and provide a scientific reference for ecological security in the study area. The specific research results were as follows: 1) This article evaluated the plateau mountain ecological security early warning system, and the application of the Granger causality test was further implemented with targeted and objective index system selection, achieving a one-to-one analysis in the results and further enriching the research theory of the importance of eco-security early warning systems. 2) On the whole, the eco-security situation in the study area is gradually moving in a positive direction, but the low level of overall eco-security continues to cause great pressure. 3) From 2005 to 2014, the study area gradually attached greater importance to the construction of ecosecurity, but the overall eco-security level is low, and the overall eco-security regulation capacity is insufficient. 4) The key eco-security pressure in the study area mainly derives from industrial and agricultural development, although the control power is gradually increasing, but the control effect is not obvious, and the contradiction between ecological security and socio-economic development is still very obvious. 5) The study area is a typical earthquake-prone area, and fi nancial input into the governance of natural geological disasters due to the high frequency of earthquakes is gradually increasing; but the study area still needs to increase its investments.
Alzheimer’s disease (AD) has become the most prevalent neurodegenerative disorder. Given the pathogenesis of AD is unclear, there is currently no drug approved to halt or delay the progression of AD. Therefore, it is pressing to explore new targets and drugs for AD. In China, polyphenolic Chinese herbal medicine has been used for thousands of years in clinical application, and no toxic effects have been reported. In the present study, using D‑galactose and aluminum‑induced rat model, the effects of paeonol on AD were validated via the Morris water maze test, open field test, and elevated plus maze test. Neuronal morphology in frontal cortex was assessed using ImageJ’s Sholl plugin and RESCONSTRUCT software. RhoA/Rock2/Limk1/cofilin1 signaling pathway‑related molecules were determined by Western blotting. Cofilin1 and p‑cofilin1 were analyzed by immunofluorescence. Results showed that pre‑treatment with paeonol attenuated D‑galactose and aluminum‑induced behavioral dysfunction and AD‑like pathological alterations in the frontal cortex. Accompanied by these changes were the alterations in the dendrite and dendritic spine densities, especially the mushroom‑type and filopodia‑type spines in the apical dendrites, as well as actin filaments. In addition, the activity and intracellular distribution of cofilin1 and the molecules RhoA/Rock2/Limk1 that regulate the signaling pathway for cofilin1 phosphorylation have also changed. Our data suggests that paeonol may be through reducing Aβ levels to alleviate the loss of fibrillar actin and dendrites and dendritic spines via the Rho/Rock2/Limk1/cofilin1 signaling pathway in the frontal cortex, and ultimately improving AD‑like behavior.
The alvarezsauroid theropod Linhenykus monodactylus from the Upper Cretaceous of Inner Mongolia, China is the first knownmonodactyl non−avian dinosaur, providing important information on the complex patterns of manual evolution seen in alvarezsauroids. Herewe provide a detailed description of the osteology of this taxon. Linhenykus shows a number of fea− tures that are transitional between parvicursorine and non−parvicursorine alvarezsauroids, but detailed comparisons also re− veal that some characters had a more complex distribution. We also use event−based tree−fitting to perform a quantitative analysis of alvarezsauroid biogeography incorporating several recently discovered taxa. The results suggest that there is no statistical support for previous biogeographic hypotheses that favour pure vicariance or pure dispersal scenarios as explana− tions for the distributions of alvarezsauroids across SouthAmerica, NorthAmerica andAsia. Instead, statistically significant biogeographic reconstructions suggest a dominant role for sympatric (or “within area”) events, combined with a mix of vicariance, dispersal and regional extinction. At present the alvarezsauroid data set is too small to completely resolve the biogeographic history of this group: future studies will need to create larger data sets that encompass additional clades.
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