Wyniki wyszukiwania

1

Papier w strategii CSR

100%

Dmochowska A.

Logistyka Odzysku

|

2011

|

nr 1

2

Wpływ soli jodowych na działanie penicyliny

63%

Dmochowska A., Loza E.

Acta Biologiae Experimentalis

|

1949

|

tom 15

|

nr Supl.13

3

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Ocena przydatności specjacji metali ciężkich w miejskich osadach pofermentacyjnych do produkcji trawników rolowanych

51%

Dmochowski D., Gajkowska-Stefanska L., Dmochowska A., Presnarowicz R. K.

Przegląd Naukowy. Inżynieria i Kształtowanie Środowiska

|

2011

|

tom 20

|

nr 3[53]

4

Analiza mozliwosci wykorzystania wspolczynnika wzbogacenia oraz specjacji metali ciezkich do oceny zagrozen odlozonych w czasie, wystepujacych w srodowisku wod powierzchniowych na terenie aglomeracji warszawskiej

51%

Dmochowski D., Predecka A., Szczepocka A., Dmochowska A.

Ochrona Środowiska i Zasobów Naturalnych

|

2007

|

nr 32

135-139

5

Transformation of Aspergillus nidulans by the argB gene

51%

Goc A., Dmochowska A., Weglenski P.

Acta Microbiologica Polonica

|

1987

|

tom 36

|

nr 1-2

6

Intracellular localization of Aspergillus nidulans ornithine carbamoyltransferase in native host celis and in Saccharomyces cerevisiae cells harbouring its cloned structural gene

45%

Maleszka R., Dmochowska A., Zaborowska D., Cybis J., Weglenski P.

Acta Biochimica Polonica

|

1986

|

tom 33

|

nr 3

7

Yeast nuclear PET127 gene can suppress deletions of the SUV3 or DSS1 genes: An indication of a functional interaction between 3' and 5' ends of mitochondrial mRNAs

39%

Wegierski T., Dmochowska A., Jablonowska A., Dziembowski A., Bartnik E., Stepien P. P.

Acta Biochimica Polonica

|

1998

|

tom 45

|

nr 4

Saccharomyces cerevisiae nuclear genes SUV3 and DSS1 encode putative RNA helicase and RNase II, respectively, which are subunits of the mitochondrial degradosome (mtEXO): a three-protein complex which has a 3' to 5' exoribonuclease activity and plays a major role in regulating stability of mitochondrial RNA. Lack of either of the two gene products results in a respiratory negative phenotype, while on the molecular level it causes a total block of mitochondrial translation, loss of the in vitro exoribonuclease activity and changes in stability and processing of many mtRNAs. We have found that the yeast nuclear gene PET127 present on a low or high copy number vector can effectively suppress the effects of the SUV3 or DSS1 gene disruptions. Since the product of the PET127 gene is involved in processing of the 5' ends of mitochondrial mRNAs, we suggest that there is a functional coupling between the 5' and 3' ends of mitochondrial mRNAs.

8

A human putative Suv3-like RNA helicase is conserved between Rhodobacter and all eukaryotes

33%

Dmochowska A., Kalita K., Krawczyk M., Golik P., Mroczek K., Lazowska J., Stepien P., Bartnik E.

Acta Biochimica Polonica

|

1999

|

tom 46

|

nr 1

We have cloned and sequenced a cDNA of the human homologue of the Saccharomyces cerevisiae Suv3 putative RNA helicase which is indispensable for mitochondrial function in yeast. The human Suv-3-like protein has a typical mitochondrial leader sequence. Northern blot data and analysis of ESTs in the data banks indicate that this human gene (SUPV3L1) is expressed in practically all tissues, though at different levels. Sequence homology analysis has shown a strong conservation of the protein in a number of eukaryotic organisms - plants, mammals and fungi, but no close homologues exist in bacteria with the exception of the purple bacterium Rhodobacter sphaeroides. This gene is thus ubiquitously present in all eukaryotic organisms.

9

Up-regulation of human PNPase mRNA by beta-interferon has no effect on protein level in melanoma cell lines

33%

Gewartowski K., Tomecki R., Muchowski L., Dmochowska A., Dzwonek A., Malecki M., Skurzak H., Ostrowski J., Stepien P. P.

Acta Biochimica Polonica

|

2006

|

tom 53

|

nr 1

Human mitochondrial polynucleotide phosphorylase (hPNPase) is an exoribonuclease localized in mitochondria. The exact physiological function of this enzyme is unknown. Recent studies have revealed the existence of a relationship between induction of hPNPase mRNA and both cellular senescence and growth arrest of melanoma cells following β-interferon treatment. The aim of this study was to verify whether the augmented hPNPase mRNA level results in increase of the protein level. In several cell lines established from five metastatic melanoma patients we did not find any such correlation. However, an elevated level of hPNPase protein was observed in interferon-induced HeLa and Jurkat cells. This increase was correlated with a slight shortening of poly(A) tails of mitochondrial ND3 transcript.

10

Differential stability of mitochondrial mRNA in HeLa cells

33%

Piechota J., Tomecki R., Gewartowski K., Szczesny R., Dmochowska A., Kudla M., Dybczynska L., Stepien P. P., Bartnik E.

Acta Biochimica Polonica

|

2006

|

tom 53

|

nr 1

The physiological significance and metabolism of oligoadenylated and polyadenylated human mitochondrial mRNAs are not known to date. After study of eight mitochondrial transcripts (ND1, ND2, ND3, ND5, CO1, CO2, ATP6/8 and Cyt. b) we found a direct correlation between the half-lives of mitochondrial mRNAs and their steady-state levels. Investigation of the mt-mRNA decay after thiamphenicol treatment indicated that three transcripts (ND2, ND3 and Cyt. b) are significantly stabilized after inhibition of mitochondrial translation. Careful analysis one of them, ND3, showed that inaccurate processing of the H-strand RNA precursor may occasionally occur between the ND3 and tRNAArg locus leading to synthesis of ND3 mRNAs lacking the STOP codon. However, analysis of the oligo(A) fraction observed in case of the ND3 indicates that partially polyadenylated mRNAs are linked rather to the transcription process than to the translation-dependent deadenylation. Analysis of ND3 mRNA turnover in cells with siRNA-mediated knock-down of the mitochondrial poly(A) polymerase shows that strongly decreased polyadenylation does not markedly affect the decay of this transcript. We present a model where oligoadenylated mitochondrial transcripts are precursors of molecules containing full length poly(A) tails.

Ograniczanie wyników

Papier w strategii CSR

Wpływ soli jodowych na działanie penicyliny

Ocena przydatności specjacji metali ciężkich w miejskich osadach pofermentacyjnych do produkcji trawników rolowanych

Analiza mozliwosci wykorzystania wspolczynnika wzbogacenia oraz specjacji metali ciezkich do oceny zagrozen odlozonych w czasie, wystepujacych w srodowisku wod powierzchniowych na terenie aglomeracji warszawskiej

Transformation of Aspergillus nidulans by the argB gene

Intracellular localization of Aspergillus nidulans ornithine carbamoyltransferase in native host celis and in Saccharomyces cerevisiae cells harbouring its cloned structural gene

Yeast nuclear PET127 gene can suppress deletions of the SUV3 or DSS1 genes: An indication of a functional interaction between 3' and 5' ends of mitochondrial mRNAs

A human putative Suv3-like RNA helicase is conserved between Rhodobacter and all eukaryotes

Up-regulation of human PNPase mRNA by beta-interferon has no effect on protein level in melanoma cell lines

Differential stability of mitochondrial mRNA in HeLa cells