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Valproic acid transfer across human placental cotyledon during dual perfusion in vitro

100%
Semczuk-Sikora A., Czuczwar S., Semczuk A., Kwasniewska A., Semczuk M.
Annals of Agricultural and Environmental Medicine
|
2010
|
tom 17
|
nr 1
153-157
2

Obstetrical consequences and experienced anxiety in women with symptoms of imminent abortion

100%
Kraczkowski J., Smolen A., Szymona K., Krzyzanowski A., Semczuk-Sikora A.
Polish Journal of Environmental Studies
|
2004
|
tom 13
|
nr Suppl.2, Part 1
Psychological factors, such as anxiety, fatigue or stress, may influence the course of pregnancy and lead to spontaneous abortions. Psychological comfort is advised to increase symptoms regression and successful termination of pregnancy. The study aimed to evaluate the intensification and characteristics of anxiety in women with symptoms of imminent abortion and to analyze the relationship between anxiety and obstetrical complications. 30 pregnant women hospitalized with the diagnosis of imminent abortion symptoms were enrolled in the study as the group. Another 30 women with normal pregnancy were the control. Authors made use of the Cattell Personality Factor Test by K. Hirszl and The Self-Reported Anxiety Scale by C.D. Spielberg, R.L. Gorsucha and R.E. Lushene. High level of anxiety that accompanies symptoms of imminent abortion is believed to be a secondary risk factor for preterm pregnancy termination.
3

Expression of genes coding for proangiogenic factors and their receptors in human placenta complicated by preeclampsia and intrauterine growth restriction

86%
Semczuk M., Borczynska A., Bialas M., Rozwadowska N., Semczuk-Sikora A., Malcher A., Kurpisz M.
Reproductive Biology
|
2013
|
tom 13
|
nr 2
4

The influence of the magnetic field on the glucose consumption and lactic acid production in the in vitro perfused human placental cotyledon

72%
Lopucki M., Kankofer M., Pietruszewski S., Kornarzynski K., Rogowska W., Stachowicz N., Semczuk-Sikora A., Czekierdowski A., Kotarski J.
Polish Journal of Environmental Studies
|
2004
|
tom 13
|
nr Suppl.2, Part 1
Objective: The biological effects of variable magnetic fields (MF) generated by widely used electrical devices on living organisms are not well understood. However MF may be potentially hazardous for pregnant women, this problem was not profoundly studied. The aim of this study was to evaluate the influence of the variable magnetic field (MF) on the placental metabolism by measurement of glucose consumption and lactate production in the human placenta under dual recirculating perfusion conditions. Material and methods: Altogether 20 term human placental cotyledons were exposed to homogeneous variable MF of B = 2 mT and f = 50 Hz (n=10; group E,) or of B = 5 mT and f = 50 Hz (n=10; group E2) during 3 hours dual close perfusion in vitro. 10 term placental cotyledons were perfused without an exposure to the MF and they served as a control group. Results: The results showed no effect of used MF on the glucose consumption either in group E, or in group E2in. There was also no influence of MF on lactic acid production in group Er In group E2, however, a significant increase of lactic acid production in the fetal circulation from 90lh to 180th minute and in the maternal circulation at 180 minute was noted. Conclusions: An increase in the lactic acid production in the group E2in observed during the experiment may result from hindered oxygen supply to the placenta and intensified anaerobic metabolism of glucose.
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