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1

Lymphocyte gamma-glutamyl transferase activity in Behcet’s disease

100%
Pabuccuoglu A., Karan A., Andac K., Yagci A.
Archivum Immunologiae et Therapiae Experimentalis
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1989
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tom 37
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nr 1-2
2
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Chicken amyloid arthropathy: serum amyloid A, interleukin-1β, interleukin-6, tumour necrosis factor-α and nitric oxide profile in acute phase (12th hour)

100%
Sevimli A., Bulbul T., Bulbul A., Yagci A.
Polish Journal of Veterinary Sciences
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2013
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tom 16
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nr 2
Acute phase response (APR) is part of the early defense system, which is triggered by different stimuli including, infection, trauma, stres, inflammation and neoplasia. The APR complex is a reaction which induces homeostasis and recovery. In this research, serum amyloid A (SAA), interlaukin (IL)-1β, IL-6, tumour necrosis factor alpha (TNF-α) and nitric oxide (NO) levels were measured 12 hours following injection. For this purpose, Thirty-two 5 weeks old laying chicken were allocated into four groups and intra-articular injections of Freund’s adjuvant were used to induce amylod arthropathy in Groups II, III and IV. Vitamin A in group II, and methylprednisolone in group IV were added to enhance and to reduce the severity of amyloidosis, respectively. At the end of the research, it was observed that TNF-α and NO increased significantly (P<0.05) in vitamin A and methylprednisolone groups whereas SAA decreased significantly (P<0.05) in all groups. It was also observed that IL-6 increased (P<0.05) in vitamin A group and decreased in all other gorups however, IL-1β decreased in vitamin A and methylprednisolone groups, while it was increased in the control group. The results of this study suggest that there is a positive correlation between serum TNF-α levels in acute and chronic phase in chickens with amyloid arthropathy.
3

Age and growth of Capoeta erhani (Actinopterygii:Cypriniformes: Cyprinidae) from the Menzelet Reservoir, Turkey

100%
Ayyildiz H., Emre Y., Ozen O., Yagci A.
Acta Ichthyologica et Piscatoria
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2014
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tom 44
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nr 2
Background. Capoeta erhani Turan, Kottelat et Ekmekçi, 2008 has an economic importance in commercial and recreational fisheries in Turkey. Knowledge of the biology of this species is very scarce. Despite the importance of this species, no research on the population dynamics such as age and growth rates has been conducted. The aim of this study was to determine the age, growth rate, and the relations between the fish size and the otolith size for C. erhani from the Menzelet Reservoir, Turkey. Materials and Methods. This study was carried out seasonally in the Menzelet Reservoir, between January and December 2012. Samples were collected using gill nets with mesh sizes ranging from 18 to 30 mm. Results. A total of 134 otoliths obtained from Capoeta erhani that ranged from 15 to 33.8 cm TL were used in the analyses. The overall male : female ratio (M : F = 1.25 : 1.00) was biased in favour of males. The Mann–Whitney test revealed significant differences between sexes, regarding TL (P < 0.05). The calculated length–weight relations were TL = 0.0097W3.0015 (r2 = 0.986) for females, TL = 0.0054W3.2011 (r2 = 0.975) for males, and TL = 0.0075W3.0892 (r2 = 0.979) for all specimens combined. The von Bertalanffy growth models were L∞ = 33.83 cm (TL), K = 0.964, t0 = –0.573 for females; L∞ = 32.02 cm (TL), K = 0.843, t0 = –0.562 for males; L∞ = 33.85 cm (TL), K = 0.821, t0 = –0.482 for all specimens. Conclusion. This study provides the first information on age, growth, and otolith morphometric parameters of Capoeta erhani. Determining the parameters of C. erhani age and growth rates will lead to the estimates of relevant parameters of population dynamics and to better understanding of the long-term changes of the stock sizes.
4

Immunihistochemical localization of epidermal growth factor receptor in testes of mice with experimentally induced diabetes

100%
Altunbas K., Ozfiliz N., Yagci A., Zik B.
Bulletin of the Veterinary Institute in Puławy
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2006
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tom 50
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nr 3
5

Immunohistochemical localization of insulin-like growth factor-I receptors in the rat intestine

100%
Zik B., Yagci A., Altunbas K., Yakisik M.
Bulletin of the Veterinary Institute in Puławy
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2006
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tom 50
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nr 2
6

Tumor regressive effect of grape juice [Enoant] on ehrlich ascites carcinoma of mice

88%
Taskin E. I., Yagci A., Firat U. B., Caner M., Dogruman H.
Medycyna Weterynaryjna
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2007
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tom 63
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nr 08
926-930
Enoant® is a nutritional reinforcement produced from the grape’s stem, peel and seeds. In recent years grape products such as wine and grape juice have acquired a great importance because of their polyphenol components, which have a strong antioxidant effect. Those antioxidant effects of polyphenols have an ability to inhibit proliferation and induce apoptosis in cancer depending on the types of cancer and application doses. In our study we have aimed to investigate the tumor regressive effects of Enoant® in solid EAC tumor model in Balb-c mice. Animals were randomly divided into 2 groups in this study. 0.5 ml of Enoant® was administered daily to ENTgroup and the same volume of NaCl 0.9% was administered to the control group. Animals continued to receive those applications till sacrification day. On the 8th day 2 × 10⁶ EAC cells in 0.5 ml NaCl 0.9% were injected subcutaneously into the mice’s napes. On day 22 all animals were sacrificed under ether anesthesia. Using PCNA immunohistochemical staining, TUNEL technique, we observed the proliferative and apoptotic cell density changes in tumor tissues as well as the effect of Enoant® on these two phenomena. Dietary Enoant® significantly regressed tumor development in mice. It has been observed that the administration of Enoant® displayed positive effects on EAC tumor’s weight and size when compared with control group animals. Mean tumor weights’ meaningfulness was p < 0.01 and mean short-long diameters’ meaningfulness were p < 0.05 and p<0.01, respectively. It has been determined that while the PCNA index was low (p < 0.05) in the Enoant® administered group, the apoptotic index that has been established with TUNEL technique was high (p < 0.01). As a result, Enoant® has a regressive function on EAC tumor cells. By inducing apoptosis, ENT inhibited the development of tumors. It is thought that ability of ENT was welded from its strong antioxidant polyphenol component. Because of that the use of Enoant® as a dietary supplement is thought to be a factor for inhibiting cancer development.
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