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Efficiency of L-carnitine endogenous biosynthesis in humans depends on the presence of cofactors of numerous enzymatic reactions. Among others, the role of cofactor is played by vitamin C and vitamin B6. The objective of our study was to evaluate the influence of vitamins C and B6 stores on plasma carnitine level in healthy humans. The examined group consisted of 52 healthy volunteers. Total (TC) and free (FC) carnitine, ascorbic acid (AA) in plasma and indices of vitamin B6 in plasma and in erythrocytes were determined. Mean TC was 52.2 ± 10.7 mmol/1 and FC 44.4 ± 9.5 mmol/1. Mean AA was 0.4 ± 0.3 mg/dl. In 40% of examined group AA levels were out of the reference range. B6 indices in plasma and erythrocytes were 1.21 ± 0.23 and 1.42 ± 0.33, respectively. Vitamin C and vitamin B6 did not influence carnitine plasma levels, that confirms the marginal role of endogenous biosynthesis in the carnitine balance in healthy subjects. Moreover, a significant distribution of vitamin C deficiency was found in the evaluated population.
The effects of unemployment also include consequences for health that are experienced by the unemployed themselves and by their families and in a broader social scale. The aim of the study was to evaluate the influence of unemployment on the health condition of the unemployed in the Lublin Region. The study was carried out in 2000-2003 and included 1560 subjects that were the unemployed registered in the Municipal and Provincial Labour Offices in Lublin, Świdnik, Lubartów, Puławy and Kraśnik. The research tool was a questionnaire survey and the research method was a diagnostic sounding.
Recently in many countries, including Poland, the problem of overweight and obesity has been increasing. Many people, despite the knowledge about the harmful effects of obesity, accept it to a considerable degree, ignoring its health consequences. The aim of the paper was to examine the incidence of overweight and obesity in the selected population as well as to evaluate the awareness of being obese and undertaking activities against it. The study included 242 residents of Staszów region. The research method was a survey questionnaire. Apart from that, all the respondents had their body mass index (BMI) calculated. In the investigated population exceeding proper body mass was common. A considerable group of the subjects did not know simple methods of evaluating the state of nutrition and had problems to estimate their own body mass. The subjects frequently were not aware of their overweight or obesity and took no actions in order to reduce their body mass.
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