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Abnormalities of diastolic filling can lead to diastolic dysfunction and heart failure. Echocardiography is a valuable tool for the evaluation of diastolic cardiac function. A high correlation between measurements of diastolic mitral inflow parameters analyzed with Doppler echocardiography and through invasive methods makes the former valuable. The aim of this study was to compare values obtained from healthy dogs to those obtained from subclinically and clinically ill dogs with mitral valve regurgitation and to determine the value of these parameters for use in diastolic myocardial dysfunction and/or diastolic heart failure diagnosis. The study was performed on 248 healthy and cardiologically ill dogs of different breeds and ages. Eleven parameters were analyzed: E wave, E-AT, E-DT, E time, A wave, A-AT, A-DT, A time, E+A time, E/A ratio, IVRT. Significant differences were found in E wave, A wave, E/A ratio, A-DT and E+A time among healthy dogs and dogs with mitral valve regurgitation. This study confirmed the value of the noninvasive echocardiographic assessment of the diastolic function in dogs. The most useful parameters include E wave, A wave, E-DT, E/A ratio and IVRT.
Echocardiography is a valuable tool for the evaluation of systolic and diastolic cardiac function. A high correlation between measurements of diastolic mitral inflow parameters analyzed with Doppler echocardiography and invasive methods makes the former valuable. The aim of this study was to ascertain if significant differences occur in diastolic myocardial parameters between dogs with no heart disease and dogs with subclinical or clinical dilated cardiomyopathy. Furthermore the aim of the study was to determine whether heart failure in dilated cardiomypathy is a result of systolic dysfunction alone or both systolic and diastolic dysfunction. Eleven parameters were analyzed: E wave, E-AT, E-DT, E time, A wave, A-AT, A-DT, A time, E+A time, E/A ratio, and IVRT. The study confirmed the value of noninvasive echocardiographic assessment of diastolic function in dogs with dilated cardiomyopathy. Significant differences were found in E wave, E-AT, E time, E/A ratio and IVRT between healthy dogs and dogs with dilated cardiomyopathy. All are characterized by a significant decrease compared to healthy dogs after taking into account age and body weight except for the E/A ratio, which significantly increased in value. There were no significant changes in any of the Doppler parameters for diastolic evaluation in subclinical cases of DCM. Advanced heart failure in dilated cardiomyopathy entails systolic and diastolic dysfunction.
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