Wyniki wyszukiwania

1

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100%

Glowacka P.

Owoce, Warzywa, Kwiaty

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2011

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nr 09

2

Brucella - virulence factors, pathogenesis and treatment

71%

Glowacka P., Zakowska D., Naylor K., Niemcewicz M., Bielawska-Drozd A.

Polish Journal of Microbiology

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2018

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tom 67

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nr 2

Brucellae are Gram-negative, small rods infecting mammals and capable of causing disease called brucellosis. The infection results in abortion and sterility in domestic animals (sheeps, pigs, rams etc). Especially dangerous for humans are: Brucella melitensis, Brucella suis, Brucella abortus, and Brucella canis that trigger unspecific symptoms (flu-like manifestation). Brucella rods are introduced via host cells, by inhalation, skin abrasions, ingestion or mucosal membranes. The most important feature of Brucella is the ability to survive and multiply within both phagocytic and non-phagocytic cells. Brucella does not produce classical virulence factors: exotoxin, cytolisins, exoenzymes, plasmids, fimbria, and drug resistant forms. Major virulence factors are: lipopolysaccharide (LPS), T4SS secretion system and BvrR/BvrS system, which allow interaction with host cell surface, formation of an early, late BCV (Brucella Containing Vacuole) and interaction with endoplasmic reticulum (ER) when the bacteria multiply. The treatment of brucellosis is based on two-drug therapy, the most common combinations of antibiotics are: doxycycline with rifampicin or fluoroquinolones with rifampicin. Currently, also other methods are used to disrupt Brucella intracellular replication (tauroursodeoxycholic acid or ginseng saponin fraction A).

3

Detection of Coxiella burnetii and Francisella tularensis in tissues of wild-living animals and in ticks of north-west Poland

61%

Bielawska-Drozd A., Cieslik P., Zakowska D., Glowacka P., Wlizlo-Skowronek B., Zieba P., Zdun A.

Polish Journal of Microbiology

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2018

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tom 67

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nr 4

This work presents results of the research on the occurrence of Coxiella burnetii and Francisella tularensis in the tissues of wild-living animals and ticks collected from Drawsko County, West Pomeranian Voivodeship. The real-time PCR testing for the pathogens comprised 928 samples of animal internal organs and 1551 ticks. The presence of C. burnetii was detected in 3% of wild-living animals and in 0.45–3.45% (dependent on collection areas) of ticks. The genetic sequences of F. tularensis were present in 0.49 % of ticks (only in one location – Drawa) and were not detected in animal tissues. The results indicate respectively low proportion of animals and ticks infected with C. burnetii and F. tularensis.

4

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Protective antigen domain 4 of Bacillus anthracis as a candidate for use as vaccine for anthrax

61%

Zakowska D., Graniak G., Rutyna P., Naylor K., Glowacka P., Niemcewicz M.

Annals of Agricultural and Environmental Medicine

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2019

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tom 26

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nr 3

Ograniczanie wyników

2 Polish Journal of Microbiology

1 Annals of Agricultural and Environmental Medicine

1 Owoce, Warzywa, Kwiaty

4 Glowacka P.

3 Zakowska D.

2 Bielawska-Drozd A.

2 Naylor K.

2 Niemcewicz M.

1 Cieslik P.

1 Graniak G.

1 Rutyna P.

1 Wlizlo-Skowronek B.

1 Zdun A.

1 Zieba P.

1 2019

2 2018

1 2011

Ograniczyć import kwiatów!?

Brucella - virulence factors, pathogenesis and treatment

Detection of Coxiella burnetii and Francisella tularensis in tissues of wild-living animals and in ticks of north-west Poland

Protective antigen domain 4 of Bacillus anthracis as a candidate for use as vaccine for anthrax