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Delayed tendon healing is still found to be among the complications that occur most often after tendon repair. The role of local injection of Artemisia absinthium was evaluated in healing of experimental Achilles tendon injury in rabbits. In nine adult New Zealand rabbits a partial thickness tenotomy was created on both hindlimbs. A. absinthium extract and normal saline were respectively injected daily to treatment and control groups for three days. On the day 7 after injury, the tendon sections showed that healing rate in A. absinthium treated group was higher than that in control group. Furthermore, at days 14 and 28, comparison between A. absinthium treated group and control group demonstrated that A. absinthium increased the healing rate but with no significance. Results of this study have showed that application of A. absinthium extract can improve healing process of damaged Achilles tendon.
Wound infection has become a major medical problem in recent years. This study was conducted to evaluate the healing activity of Capparis spinosa against surgical wounds infected by Escherichia coli. Twenty male rats were divided into two groups. Excisions were created surgically on the animals’ skin and then infected with E coli. Group 1 was treated with C spinosa while Group 2 was untreated. Wound biopsy specimens were collected on days 5, 10 and 16 and analyzed. Results showed that the hydroxyproline content in treatment group was significantly higher in various post wounding days. Protein content increased gradually in ten days. Results of histopathological studies showed moderate to intense granulation tissue formation in treated group on day 10. The histopathological studies showed, that the new epidermis in treated group was thicker than in control group on day 16 post wounding. The present study has demonstrated that ethanol extract of C spinosa includes properties that accelerate wound healing activities.
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