Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 8

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
Ahmadian M, Wistuba II, Fong KM, Behrens C, Kodagoda DR, Saboorian MH, Shay J, Tomlinson GE, Blum J, Minna JD, Gazdar AF. (1997) Analysis of the FHITgene and FRA3B region in sporadic breast cancer, preneoplastic lesions, and familial breast cancer probands. Cancer Res.; 57: 3664-8. Baffia R, Veronese ML, Santoro B, Mandes B, Palazzo JP, Rugge M, Santoro E, Croce CM, Huebner K. (1998) Laoo os FIHTexpression in gastric carcinoma. Cancer Res.; 58: 4708-14. Barnes LD, Garrison PN, Siprashvili Z, Guranowski A, Robinson AK, Ingram SW, Croce CM, Ohta M, Huebner K. (1996) Fhit, a putative tumor suppressor in humans is a dinucleoside 5',5''-P1,P3-triphosphate hydrolase. Biochemistry.; 35: 11529-35. Berns EM, Klijn JG, van Staveren IL, Portengen H, Noordegraaf E, Foekens JA. (1992) Prevalence of amplification of the oncogenes c- myc, HER2/neu, and int-2 in one thousand human breast tumors: correlation with steroid receptors. Eur J Cancer.; 28: 697-700. Berns EM, Foekens JA, van Staveren IL, van Putten WL, de Koning HY, Portengen H, Klijn JG. (1995) Oncogene amplification and prognosis in breast cancer: relationship with systemic treatment. Gene.; 159: 11-8. Bloom HJ, Richardson WW. (1957) Histological grading and prognosis in breast cancer. Br J Cancer.; 11: 359-77. Borg A, Baldetrop B, Ferno M, Olsson H, Sigurdsson H. (1992) c- myc amplification is an independent prognostic factor in postmenopausal breast cancer. Int J Cancer.; 51: 687-91. Campiglio M, Pekarsky Y, Menard S, Tagliabue E, Pilotti S, Croce CM. (1999) FHIT loss of function in human primary breast cancer correlates with advanced stage of the disease. Cancer Res.; 59: 3866-9. Champeme MH, Bieche I, Hacene K, Lidereau R. (1994) Oncogene amplification per se: an independent prognostic factor in human breast cancer. Mol Carcinog.; 11: 189-91. Chen Y, Dong J, Lu Y, McGee JO. (1995) Quantitative detection of amplification of proto-oncogenes in breast cancer. Chin Med J.; 108: 849-54. Chrzan P, Skokowski J, Karmolinski A, Pawelczyk T. (2001) Amplification of c- myc gene and overexpression of c-Myc protein in breast cancer and adjacent non-neoplastic tissue. Clin Biochem.; 34: 557-62. Deming SL, Nass SJ, Dickson RB, Trock BJ. (2000) c- myc amplification in breast cancer: a meta-analysis of its occurrence and prognostic relevance. Br J Cancer.; 83: 1688-95. Druck T, Hadaczek P, Fu TB, Ohta M, Siprashvili Z, Baffa R, Negrini M, Kastury K, Veronese ML, Rosen D, Rothstein J, McCue P, Cotticelli MG, Inoue H, Croce CM, Huebner K. (1997) Structure and expression of the human FHIT gene in normal and tumor cells. Cancer Res.; 57: 504-12. Fong KM, Biesterveld EJ, Virmani A, Wistuba I, Sekido Y, Bader SA, Ahmadian M, Ong ST, Rassool FV, Zimmerman PV, Giaccone G, Gazdar AF, Minna JD. (1997) FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHITcDNA splicing aberrations. Cancer Res.; 57: 2256-67. Guo Z, Johansson SL, Rhim JS, Vishwanatha JK. (2000) Fragile histidine triad gene expression in primary prostate cancer and in an in vitro model. Prostate.; 43: 101-10. Hayashi S, Tanimoto K, Hajiro-Nakanishi K, Tsuchiya E, Kurosumi M, Hagashi Y, Imai K, Suga K, Nakachi K. (1997) Abnormal FHIT transcripts in human breast carcinomas: a clinicopathological and epidemiological analysis of 61 Japanese cases. Cancer Res.; 57: 1981-5. Huiping C, Jonasson JG, Agnarsson BA, Sigbjornsdottir BI, Huebner K, Ingvarsson S. (2000) Analysis of the fragile histidine triad ( FHIT) gene in lobular breast cancer. Eur J Cancer.; 36: 1552-7. Ingvarson S, Sigbjornsdottir BI, Huiping C, Jonasson JG, Agnarsson BA. (2001) Alterations of the FHIT gene in breast cancer: association with tumor progression and patient survival. Cancer Detect Prev.; 25: 292-8. Lonn U, Lonn S, Nilsson B, Stenkvist B. (1995) Prognostic value of erb-B2 and myc amplification in breast cancer imprints. Cancer.; 75: 2681-7. Mark HF, Aswad B, Bassily N, Taylor W, Brown S, Sun CL, Samy M, Zolnierz K, Wong E, Bland KI, Hsu PH. (1999) HER-2/neu gene amplification in stages I-IV breast cancer detected by fluorescent in situ hybridization. Genet Med.; 1(3): 98-103. Negrini M, Monaco C, Vorechovsky I, Ohta M, Druck T, Baffa R, Huebner K, Croce CM. (1996) The FHIT gene at 3p14.2 is abnormal in breast carcinomas. Cancer Res.; 56: 3173-9. Ohta M, Inoue H, Cotticelli MG, Kastury K, Baffa R, Palazzo J, Siprashvili Z, Mori M, McCue P, Druck T, Croce CM, Huebner K. (1996) The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell.; 84: 587-97. Otterson GA, Xiao G-H, Geradts J, Jin F, Chen W, Niklinska W, Kaye FJ, Yeung RS. (1998) Protein expression and functional analysis of the FHIT gene in human tumor cells. J Natl Cancer Inst.; 90: 426-32. Pandis N, Bardi G, Mitelman F, Heim S. (1997) Deletion of the short arm of chromosome 3 in breast tumors. Genes Chromosomes Cancer.; 18: 241-5. Sakowicz M, Grden M, Pawelczyk T. (2001) Expression level of adenosine kinase in rat tissues. Lack of phosphate effect on the enzyme activity. Acta Biochim Polon.; 48: 745-55. Siprashvili Z, Sozzi G, Barnes LD, McCue P, Robinson AK, Eryomin V, Sard L, Tagliabue E, Greco A, Fusetti L, Schwartz G, Pierotti MA, Croce CM, Huebner K. (1997) Replacement of Fhit in cancer cells suppresses tumorigenicity. Proc Natl Acad Sci US A.; 94: 13771-6. Sozzi G, Tornielli S, Tagliabue E, Sard L, Pezzella F, Pastorino U, Minolitti F, Pilotti S, Ratcliffe C, Veronese ML, Goldstraw P, Huebner K, Croce CM, Pierotti MA. (1997) Absence of Fhit protein in primary lung tumors and cells lines with FHIT gene abnormalities. Cancer Res.; 57: 5207-12. Watson PH, Safneck JR, Le K, Dubik D, Shiu RP. (1993) Relationship of c- myc amplification to progression of breast cancer from in situ to invasive tumor and lymph node metastasis. J Natl Cancer Inst.; 85: 902-7. Yoshino K, Enomoto T, Nakamura T, Sun H, Ozaki K, Nakashima R, Wanada H, Saitoh J, Watanabe Y, Noda K, Murata Y. (2000) FHIT alterations in cancerous and non-cancerous cervical epithelium. Int J Cancer.; 85: 6-13. Yuan BZ, Keck-Waggoner C, Zimonjic DB, Thorgeirsson SS, Popescu NC. (2000) Alterations of the FHIT gene in human hepatocellular carcinoma. Cancer Res.; 60: 1049-53. Zou TT, Lei J, Shi YQ, Yin J, Wang S, Souza RF, Kong D, Shimada Y, Smolinski KN, Greenwald BD, Abraham JM, Harpaz N, Meltzer SJ. (1997) FHIT gene alterations in esophageal cancer and ulcerative colitis (UC). Oncogene.; 15: 101-15. Zou M, Shi Y, Farid NR, al-Sedairy ST, Paterson MC. (1999) FHIT gene abnormalities in both benign and malignant thyroid tumors. Eur J Cancer.; 35: 467-72.
The Saccharomyces cerevisiae spindle pole body (SPB) consists of numerous pro­teins forming the outer, inner and central plaques. The protein Cnm67 is an important component of the outer plaque. The C-terminus of this protein contains a determinant important for its SPB localization. We identified a protein encoded by YOR129c which interacts with this C-terminus in the two-hybrid system. YOR129c and CNM67 exhibit weak genetic interaction. The double deletion strain yor129cΔ cnm67Δ exhibits mod­erately increased resistance to 0.1 M LiCl and hygromycin B compared with the cnm67Δ single mutant. We propose that the YOR129c protein is an accessory factor associated with the cytoplasmic face of SPB and plays a role in cation homeostasis and/or multidrug resistance.
The evolutionarily conserved proteins forming sister chromatid cohesion complex are also involved in the regulation of gene transcription. The participation of SA2p (mammalian ortholog of yeast Irr1p, associated with the core of the complex) in the regulation of transcription is already described. Here we analyzed microarray profiles of gene expression of a Saccharomyces cerevisiae irr1-1/IRR1 heterozygous diploid strain. We report that expression of 33 genes is affected by the presence of the mutated Irr1-1p and identify those genes. This supports the suggested role of Irr1p in the regulation of transcription. We also indicate that Irr1p may interact with elements of transcriptional coactivator Mediator.
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.