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Silurian and Devonian corals of Japan

100%

Kato M., Minato M., Nikawa I., Kawamura M., Nakai H., Haga S.

Acta Palaeontologica Polonica

1980

tom 25

nr 3-4

Coral assemblages and their faunal sequence for the Silurian and Devonian in four major regions of Japan are reviewed. In Yokokurayama the G₂ fauna with Halysites is Early to Middle Silurian and the G₃ fauna with Schedohatysites is mainly Late Silurian. The Kawauchi Formation of Hikoroichi corresponds to G₃ and a part of G₂. The Okuhinotsuchi Formation of Arisu is mainly correlatable with the G₂. The Ohno fauna of Hikoroichi with Xystriphyllum and the Fukuji fauna are both Early Devonian in age, but their composition is quite different from each other. The Nakazato fauna of Hikoroichi is Middle Devonian. These faunas are composed mostly of cosmopolitan genera. The development of coral faunas may indicate the strong contrast in litho- and biofacies between the Pacific side (outer zone of Southwest Japan and Northeast Japan) and the Japan Sea side (inner zone of Southwest Japan) during the Silurian and Devonian.

Contribution of the calcineurin signaling pathway to overload-induced skeletal muscle fiber-type transition

100%

Miyazaki M., Hitomi Y., Kizaki T., Ohno H., Haga S., Takemasa T.

Journal of Physiology and Pharmacology

2004

tom 55

nr 4

Skeletal muscle is highly adaptable, being capable of undergoing changes in its structural and functional properties in response to physiological stimuli. The fast-to-slow muscle fiber-type transition is evoked by increased motor nerve activity. Recently, the calcineurin (CaN) signaling pathway has been implicated in the transcriptional regulation of slow muscle fiber genes. Here we investigated the effect of treatment with a CaN-specific inhibitor, FK506, on skeletal muscle fiber-type transition in functionally overloaded muscles. The overloaded plantaris muscle showed fast-to-slow muscle fiber type transition, i.e., a decrease in myosin heavy chain (MHC) IIb, an increase in MHCIIa+d/x, and new expression of MHCI. In the FK506-administered group, however, overload-induced muscle fiber-type transition was completely prevented. We have demonstrated, therefore, that the CaN signaling pathway is required for fast-to-slow skeletal muscle fiber-type transition. Furthermore, we also confirmed that the protein expression levels of downstream effectors of CaN signaling exhibit a transient increase in the early phase of the overloaded condition.

Ograniczanie wyników

1 Acta Palaeontologica Polonica

1 Journal of Physiology and Pharmacology

2 Haga S.

1 Hitomi Y.

1 Kato M.

1 Kawamura M.

1 Kizaki T.

1 Minato M.

1 Miyazaki M.

1 Nakai H.

1 Nikawa I.

1 Ohno H.

1 Takemasa T.

1 2004

1 1980

Wyniki wyszukiwania

Silurian and Devonian corals of Japan

Contribution of the calcineurin signaling pathway to overload-induced skeletal muscle fiber-type transition