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1

The variability of the small cardiac vein in the adult human heart

100%
Cendrowska-Pinkosz M.
Folia Morphologica
|
2004
|
tom 63
|
nr 2
Direct analyses were performed on 50 hearts submitted for post mortem examination. The remaining hearts were examined by the corrosion method. The aim of the work was to assess the morphology of the small cardiac vein. The small cardiac vein, which runs along the back surface of the coronary sulcus, would usually drain into the coronary sinus at its right side (86% of cases). Cases of the small cardiac vein draining into the middle cardiac vein were also noticed (12%) or directly into the right atrium (1%). In 1% of the preparations it ran along the right margin in the direction of the apex of the heart. In 30% of the corrosion preparations the small cardiac vein was not accessible with the help of corrosion. In 24% of the dissection preparations it was not possible to reach the small cardiac vein with the help of dissection. A statistically significant relationship was observed between the frequency of the presence or absence of the small cardiac vein and the sex of the donor (p > 0.001). In the group examined the percentage of men who did not have the small cardiac vein was 6 times higher than among the woman. There was no evidence for any statistically significant dependence between the frequency of occurrence or of absence of the small cardiac vein and the technique employed.
2

Pathogencity of the family Legionellaceae

63%
Palusinska-Szysz M., Cendrowska-Pinkosz M.
Archivum Immunologiae et Therapiae Experimentalis
|
2009
|
tom 57
|
nr 4
279-290
3

Analysis of the course and the ostium of the oblique vein of the left atrium

63%
Cendrowska-Pinkosz M., Urbanowicz Z.
Folia Morphologica
|
2000
|
tom 59
|
nr 3
Considerating the origin of the coronary sinus and the oblique vein of the left atrium, both are remnants of the left horn of the embryonal venous sinus. The studies were carried out on 100 human cadaver hearts. The causes of death were not cardiac reasons, no detectable changes in the coronary arteries. In the study, dissections and corrosion technique were used. Heart veins were filled by metacrylan through the coronary sinus. The beginning, the course, the tributaries and the ostium oblique vein of the left atrium to the coronary sinus were investigated. The variability of the length and the venous tributaries and the ostium of the oblique vein of the left atrium were noticed. The variability of the venous tributaries (the dendritic, forked and simple types of the tributaries) was noticed. Four groups of ostium were observed. The ostium oblique vein of the left atrium was situated at the level of: the posterior vein of the left ventricle and also the great cardiac vein, the posterior vein of the left ventricle, the great cardiac vein and the independence ostium.
4

Influence of garlic, synthetic 1,2,4-triasole derivative and herbal preparation Echinovit C on selected indices of turkey-hens non-specific immunity

51%
Truchlinski J., Krauze M., Cendrowska-Pinkosz M., Modzelewska-Banachiewicz B.
Polish Journal of Veterinary Sciences
|
2006
|
tom 09
|
nr 1
Successful results of earlier studies on testing the immune-modulating and anti-microbial properties of 1,2,4-triasole derivative as well as benefitial application of natural bio-stimulators in animal's prophylaxis and treatment inspired us to undertake further investigations. The aim of the present study was to evaluate and compare the prophylaxis effects of two natural immune-modulating agents, garlic (Allium sativum) extract and Echinovit C preparation and synthetic derivative of 1,2,4-triasole on non-specific immunity indices in slaughter turkey-hens. The results obtained suggest that the strongest stimulatory effect is exerted by garlic followed by 1,2,4-triasole derivative and Echinacea juice. Immune-modulating action of the substances applied was manifested by an increase in cellular immune parameters: the percentage of phagocyting cells, NBT-positive granulocytes and lysozyme level.
5

Some biochemical parameters of blood plasma of turkey-hens following administration of 1,2,4-triasole derivative

51%
Krauze M., Truchlinski J., Cendrowska-Pinkosz M.
Polish Journal of Veterinary Sciences
|
2007
|
tom 10
|
nr 2
The present study involved 180 slaughter turkey-hens of heavy Big-6 type divided into four groups (in triplicate repetition for 15 birds). All the birds were fed with the same standard full-dose mixtures in 5-stage system. The turkey-hens of groups I, II and III were given 1,2,4-triasole derivative (3-(2-pyridil)-4-phenyl-l,2,4-triasole-5-carboxylic acid), which has antibacterial, antifungal and immunomodulating properties, in amount of 50, 75 and 100 |ig per 1 dm3 of water. Group IV - control was given water without the additive. The 1,2,4-triasole derivative was given to drinking water, starting from the first day of bird's life and for the whole rearing period. The present results of biochemical analysis of blood plasma showed that addition of examined substance significantly reduced concentration of protein, glucose, triglycerides and uric acid as compared to control. It was stated that tested 1,2,4-triasole derivative elevated the level of HDL fraction percentage and alkaline phosphatase activity in blood plasma.
6

Activity of some lysosomal enzymes in adrenal cortex during experimental alloxan-induced diabetes mellitus in rabbits

45%
Grzebalska A. M., Cendrowska-Pinkosz M., Luszczewska-Sierakowska I., Burdan F., Krauze M.
Medycyna Weterynaryjna
|
2014
|
tom 70
|
nr 04
The aim of the study was the evaluation of changes in the adrenal cortex lysosomal enzymes activity during experimental alloxan-induced diabetes mellitus in rabbits. We checked the activity of acid phosphatase, β-D-galactosidase, N-acetyl-β-D-glucosaminidase (NAGL) and lipase. The study was performed on 124 rabbits divided into five groups: one control and four experimental. Diabetes mellitus was induced by a single injection of 10% alloxan solution into the auricular vein in a dose of 10 mg per kg body weight. Animals from experimental groups were killed in the 21st, 42nd, 90th and 180th days of the study. Adrenal glands were removed. Enzymes activity was assayed by spectrophotometric methods. Changes in free and bound fractions of examined lysosomal enzymes activity were noticed already in the 21st day of diabetes. The most escalated changes were observed in the 42nd day of the study. Performed statistical variance analysis demonstrated statistically highly significant differences for activity of both fractions of NAGL and lipase, as well as for free fraction activity of acid phosphatase and β-D-galactosidase. The obtained data confirmed the influence of diabetes mellitus on changes in the activity of examined lysosomal enzymes in the adrenal cortex.
7

Anatomical eponyms - unloved names in medical terminology

45%
Burdan F., Dworzanski W., Cendrowska-Pinkosz M., Burdan M., Dworzanska A.
Folia Morphologica
|
2016
|
tom 75
|
nr 4
Uniform international terminology is a fundamental issue of medicine. Names of various organs or structures have developed since early human history. The first proper anatomical books were written by Hippocrates, Aristotle and Galen. For this reason the modern terms originated from Latin or Greek. In a modern time the terminology was improved in particular by Vasalius, Fabricius and Harvey. Presently each known structure has internationally approved term that is explained in anatomical or histological terminology. However, some elements received eponyms, terms that incorporate the surname of the people that usually describe them for the first time or studied them (e.g., circle of Willis, follicle of Graff, fossa of Sylvious, foramen of Monro, Adamkiewicz artery). Literature and historical hero also influenced medical vocabulary (e.g. Achilles tendon and Atlas). According to various scientists, all the eponyms bring colour to medicine, embed medical traditions and culture to our history but lack accuracy, lead of confusion, and hamper scientific discussion. The current article presents a wide list of the anatomical eponyms with their proper anatomical term or description according to international anatomical terminology. However, since different eponyms are used in various countries, the list could be expanded. (Folia Morphol 2016; 75, 4: 413–438)
8

Urinary bladder diverticulum as an unusual content of the inguinal canal

39%
Burdan F., Staroslawska E., Mocarska A., Cendrowska-Pinkosz M., Caban M., Zelazowska-Cieslinska I., Kubiatowski T.
Folia Morphologica
|
2014
|
tom 73
|
nr 4
The inguinal urinary bladder hernia is a rare pathology observed mostly in males. A new case of asymptomatic reducible acquired inguinal hernia was revealed in a 54-year-old male during computed tomography (CT) undertaken for oncological follow-up. The right nephrectomy was previously performed due to clear cell carcinoma. The hernia was not visible on the CT 6 months before and on ultrasound performed after voiding. Slight herniation with a wide invagination of transversalis fascia but with empty bladder was seen on CT 4 months after the initial detection of hernia. (Folia Morphol 2014; 73, 4: 500–503)
9

The effect of a rat diet without added Cu on redox status in tissues and epigenetic changes in the brain

39%
Ognik K., Tutaj K., Cholewinska E., Cendrowska-Pinkosz M., Dworzanski W., Dworzanska A., Juskiewicz J.
Annals of Animal Science
|
2020
|
tom 20
|
nr 2
10

Effect of iodothyronine hormone status on doxorubicin related cardiotoxicity

33%
Dudka J., Mandziuk S., Madej-Czerwonka B., Sierocinska-Sawa J., Walczyna B., Korga A., Cendrowska-Pinkosz M., Burdan F.
Folia Morphologica
|
2013
|
tom 72
|
nr 4
The anthracycline anticancer agent doxorubicin has been recognised to induce a dose-dependent cardiotoxicity. The chronic form of such complication is characterised by an irreversible cardiac damage and congestive heart failure. Although the pathogenesis of anthracycline cardiotoxicity seems to be multifactorial, the pivotal role has been attributed to reactive oxygen species formation. Because redox equilibrium in cardiomyocytes may be regulated via iodothyronine hormones, the aim of the study was to appraise the effect of hypothyroidism on heart damages induced by doxorubicin. The rats received methimazole in drinking water (0.001 and 0.025%) after doxorubicin administration (2.0, 5.0 and 15 mg/kg). The cardiac morphology and blood biochemical markers of heart damage were assessed. Decreased levels of iodothyronine hormones had not significant impact on cardiac morphological changes and no effect on the level of B-type natriuretic peptide in rats receiving doxorubicin. Lower hormonal levels had sporadic, diverse effect on blood transaminases, lactate dehydrogenase and creatine kinase levels, but any relation to time, doxorubicin doses and hypothyroid status was found. Hypothyreosis leads to increase in fatty acid binding protein in rats receiving higher dose of doxorubicin. Hypothyreosis had no effect on heart stretching and on necrosis at morphological level, but caused biochemical symptoms of cardiomyocyte necrosis in rats receiving doxorubicin. (Folia Morphol 2013; 72, 4: 340–348)
11

Influence of caffeine used at various temperature ranges on the concentrations of glucose and total serum protein as well as body weight gain in pregnant rats

33%
Cendrowska-Pinkosz M., Luszczewska-Sierakowska I., Dworzanski W., Tomaszewski M., Krauze M., Grzebalska A. M., Madej-Czerwonka B., Burdan F.
Bulletin of the Veterinary Institute in Puławy
|
2014
|
tom 58
|
nr 2
Caffeine (120 mg/kg) was administered intragastrically to pregnant rats daily on gestational days 8-21. An increase in serum concentration of glucose and total protein was found in animals, which were given caffeine. The protein content proved to be highly significant in the experimental group of animals. The control group showed a negative interdependence between body weight gain and glucose concentration. No correlation was found between body weight gain and total protein concentration, yet the glucose concentration significantly influenced the total protein concentration in this group of animals. Among animals which received caffeine, correlations between total protein and glucose concentrations were observed. The analysis did not show that the glucose or total protein concentration significantly influenced the body weight gain of pregnant female rats in the experimental group. The research conducted suggests the possibility of modulating effects of caffeine on adaptive processes during pregnancy.
12

Effect of hypoxia on toxicity induced by anticancer agents in cardiomyocyte culture

33%
Mandziuk S., Kus P., Dudka J., Madej-Czerwonka B., Cendrowska-Pinkosz M., Iwan M., Luszczewska-Sierakowska I., Korga A.
Medycyna Weterynaryjna
|
2014
|
tom 70
|
nr 05
The main goal of the study was to determine whether hypoxia augments the toxicity of anticancer drugs towards cardiomyocytes. Drugs selected for this experiment were those that disturb the cardiac redox equilibrium. Cardiomyocytes were incubated for 24 h with doxorubicin, tirapazamine, and 5-fluorouracil, each at three doses, under normoxia and under 50% and 90% hypoxia. The cytotoxic effect was evaluated on the basis of the percentage of living cells, cell vitality (assessed by the MTT assay), and morphology. In addition, the oxidative marker and pH value were determined. Varied protective effects of hypoxia on cell morphology were observed in all cases except the medium concentration of tirapazamine. The 50% hypoxia prevented the toxic effects of all tested drugs. The 90% hypoxia, on the other hand, was effective against the cytotoxic action of doxorubicin and 5-fluoruracil, but the cytotoxicity of tirapazamine increased. It was found that under the 90% hypoxia the oxidative stress observed under normoxia and the 50% hypoxia was greatly reduced. The study revealed that the above drugs did not activate anaerobic glycolysis.
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