Wyniki wyszukiwania

Sortuj według:

Ogranicz wyniki do:

Precontact 50-kHz ultrasonic vocalizations and sexual performance in WAG/Rij and Spraque-Dawley male rats: effect of naltrexone

100%

Bialy M., Strefnel M., Nikolaev-Diak A., Socha A., Nikolaev E., Boguszewski P.

Acta Neurobiologiae Experimentalis

2013

tom 73

nr Suppl.1

As we found previously, ultrasonic vocalizations in the 50-kHz band emitted before a female is introduced into a copulatory chamber (precontact vocalizations – PVs) is useful parameter describing the rewarding value of socio-sexual contact in male rats. In the present experiments, we have investigated the influence of opioid receptors on PVs in sexually experienced rats. The behavioral effects of an i.p. injection of the opioid receptors antagonist – naltrexone were analyzed in six month old sexually experienced Wag/Rij (rats with genetic absence epilepsy) and Sprague-Dawley male rats. We found higher number of PVs in WAG/Rij compared to Sprague-Dawley males. Naltrexone (3 mg/kg) significantly diminished number PVs. Spectral analysis of PVs ultrasonic vocalizations did not detect significant changes in frequency of calls after physiological saline and naltrexone treatment. Opioid receptors are involved in PVs probably via changes in rewarding value of socio-sexual contacts. Our results have shown that rewarding system of Wag/Rij rats with absent epilepsy is sensitive to socio-sexual reward and seems to be even more sensitive that in Sprague-Dawley males.

Ograniczanie wyników

1 Acta Neurobiologiae Experimentalis

1 Bialy M.

1 Boguszewski P.

1 Nikolaev E.

1 Nikolaev-Diak A.

1 Socha A.

1 Strefnel M.

1 2013

Wyniki wyszukiwania

Precontact 50-kHz ultrasonic vocalizations and sexual performance in WAG/Rij and Spraque-Dawley male rats: effect of naltrexone