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1

Selected tumour biomarker levels in sheep with pulmonary adenomatosis

100%
Ozkan C., Yildirim S., Huyut Z., Ozbek M.
Journal of Veterinary Research
|
2020
|
tom 64
|
nr 1
2

Decreased serum adenosine deaminase activities in Van cats with feline retroviruses infections

100%
Altug N., Yuksek N., Agaoglu Z. T., Ozkan C.
Medycyna Weterynaryjna
|
2007
|
tom 63
|
nr 02
184-186
This aim of the study was to determine the activity of ADA serum and isoenzyme in feline retroviral infections. The study involved 6 FeLV seropositive, 4 FIV seropositive and 10 healthy seronegative cats aged between 1-8 years. Haematological, serum enzyme acivity (AST; ALT; ALP; GGT) as well as ADA serum and isoenzyme activity were determined in all the cats. Haematological parameters were within the normal range except for the platelet count in FIV seropositive cats (p<0.05). Serum enzyme activity was unchanged except for the AST concentration in FeLV and FIV seropositive cats compared to the healthy subjects. ADA serum and ADA1 concentrations were lower in the seropositive group than in the seronegative group. However, the decrease in ADA serum and ADA1 concentrations in FIV seropositive cats (p<0.01) was more significant than that of FeLV seropositive cats (p<0.05). In conclusion, decreased ADA and ADA1 activity in feline retrovirus infections may be significant.
3

Parasites detected in neonatal and young calves with diarrhoes

100%
Goz Y., Altug N., Yuksek N., Ozkan C.
Bulletin of the Veterinary Institute in Puławy
|
2006
|
tom 50
|
nr 3
4

Evaluation of acute phase protein levels and some cytokine levels in pneumonic calves

88%
Akgul O., Kozat S., Ozkan C., Kaya A., Akgul Y.
Medycyna Weterynaryjna
|
2019
|
tom 75
|
nr 03
This study was carried out to determine the levels of various cytokines (TNF-α, IL-6, IL-8) and acute phase proteins (haptoglobin, C-reactive protein, serum amyloid A, alpha 1-acid glycoprotein, lactoferrin, and fibrinogen) in pneumonic calves, to reveal changes in these parameters depending on etiologic factors (bacterial, viral, bacterial + viral) in calf pneumonia, and to determine whether these parameters could be used for diagnosis and prognosis of the disease. The study was carried out on a total of 50 calves consisting of 10 healthy and 40 pneumonic animals aged 1 to 6 months. The pneumonic calves were classified into three groups: bacterial, viral and mixed (bacterial + viral). It was found that the levels of IL-6, IL-8, CRP, and TNF-α were statistically higher in the pneumonic calves than in the control group animals. It was found that the increase in levels of Serum IL-6, IL-8, and CRP were highest in the mixed infection group (bacterial + viral) and lowest in the virally infected group. Similarly, serum levels of Hp, CRP, SAA, α-1-AGP, and LF were found to be more statistically significant (P <0.01) in the infected calves than in the control group animals, but changes in fibrinogen levels were not statistically significant. Although the TP and ALB levels in the pneumonic calves were numerically higher than the same parameters in the control group, this was not statistically significant (P > 0.05). As a result, this study showed that serum levels of cytokines (IL-6, IL-8, TNF-α) and serum concentrations of acute-phase proteins (Hp, CRP, SAA, α-1-AGP, and LF) are significantly higher in the pneumonic calves than in the control group calves. Furthermore, the assessment of cytokine and acute phase protein levels can play an important role in the early diagnosis of calf pneumonia. This early diagnosis can help prevent deaths caused by pneumonia, which is the leading cause of major losses, and can also be helpful in the early treatment of pneumonia in the veterinary clinical field.
5

Serum malondialdehyde, coenzyme Q10 and 8-hydroxy-2-deoxyguanosine levels in calves with foot-and-mouth disease

88%
Ozkan C., Huyut Z., Yildirim S., Ozbek M., Icen H.
Medycyna Weterynaryjna
|
2018
|
tom 74
|
nr 11
Foot-and-mouth disease (FMD) is an acute, contagious viral disease in cattle that is associated with enormous economic losses in Turkey and worldwide. The purpose of this study was to determine changes in serum malondialdehyde (MDA), coenzyme Q10 (CoQ10), 8-hydroxy-2-deoxyguanosine (8-OHdG) and deoxyguanosine (dG) and to perform histopathological examinations in calves with FMD. Thirty calves were studied, 20 of which were infected with FMD and 10 were free of the disease. Following a routine clinical examination, blood samples were obtained, and serum MDA, CoQ10, 8-OHdG and dG levels were determined. Necropsy and histopathological examinations were performed on dead calves with FMD. MDA and 8-OHdG/10⁶dG levels were significantly higher in calves with FMD than in the control group. However, the increase in CoQ10 levels in calves with FMD, compared with the control group, was not statistically significant. Macroscopic examination of the heart tissue of calves with acute myocarditis revealed the presence of pale, yellowish gray-white necrotic muscle fibers in the ventricular wall of the heart. The muscle fibers in the myocardium were swollen and exhibited pyknotic nuclei and intense lymphocytic cell infiltration. In longitudinal sections, the muscle fibers were non-striated, swollen, and homogenously pink and contained pink nuclei. Between muscle fibers, intense mononuclear cell infiltration was observed. The findings of the present study indicate that oxidative stress is significantly increased in calves with FMD, and that oxidative DNA damage may play an important role in the etiopathogenesis of FMD. This is the first study to report CoQ10 and 8-OHdG levels in calves with FMD, and its findings may serve as the basis for future studies on this subject.
6

Determination of Cryptosporidium spp. in Van cats by nested PCR

88%
Orunc Kilinc O., Yilmaz A. B., Goz Y., Ozkan C., Denizhan V.
Medycyna Weterynaryjna
|
2018
|
tom 74
|
nr 07
The present study was conducted to investigate the presence of Cryptosporidium spp. agents in cats from the Turkish Van Cat Shelter at YüzüncüYıl University by a modified Ziehl-Neelsen staining method and nested PCR. Individual stool samples were obtained from 30 adult females, 30 adult males and 40 kittens – a total of 100 Van cats were analyzed in the study. A simplified formol-ether concentration method was applied to all samples. The samples were then examined microscopically by a modified Ziehl-Neelsen staining method. As a result of the staining, Cryptosporidium spp. oocysts were identified in stool samples of 3 kittens in the microscopic examination. After that, PCR and nested-PCR were conducted with suitable primers. Nested PCR identified 5 kittens (5%) as positive. As a result, it was concluded that nested PCR was a superior diagnostic method for Cryptosporidium diagnosis compared with staining methods and that infected cats could be a health hazard for other cats and individuals, since Cryptosporidium spp. agents infect via the faecal-oral route. Therefore, we believe it is necessary to raise the awareness of people in contact with cats.
7

Prevalence of feline retrovirus infections in Van cats

88%
Yuksek N., Kaya A., Altug N., Ozkan C., Agaoglu Z. T.
Bulletin of the Veterinary Institute in Puławy
|
2005
|
tom 49
|
nr 4
8

Rupture of the gastrocnemius muscle in a cow two months after twin birth

76%
Altug N., Ozkan C., Yuksek N., Karasu A., Keles I., Agaoglu Z. T., Ilhan F.
Bulletin of the Veterinary Institute in Puławy
|
2007
|
tom 51
|
nr 4
9

Determination of selected hormones and biochemical parameters in Turkish Van cats with tail gland hyperplasia

76%
Ozkan C., Kayar A., Kaya A., Yildirim S., Iskefli O., kozat S., Akgul Y.
Medycyna Weterynaryjna
|
2020
|
tom 76
|
nr 01
The present study was performed on Turkish Van cats with tail gland hyperplasia in order to determine changes in some hormone levels and biochemical parameters. Animal material consisted of 18 male Van cats of between 2-8 years of age, 12 with tail gland hyperplasia and 6 unaffected cats as the control group. Following routine clinical examination, hormone levels and biochemical parameters were measured by obtaining blood samples, and biopsy samples were obtained from the region and examined under a light microscope. When compared with the control group, testosterone levels were high although the difference between groups was not statistically significant. Similarly, no statistical significance was found between the groups in terms of other hormones. Among the hormonal parameters, the only remarkable increase was seen in the testosterone level. Among biochemical parameters, the alkaline phosphatase (ALP), aspartate amino transferase (AST), cholesterol and triglyceride levels were statistically different, while other biochemical parameters were not statistically significant. While AST and cholesterol results were increased, ALP and triglyceride levels were decreased. As a result, we conclude that the disease is an important problem which occurs extensively in mature male Van cats, particularly during and after mating periods. We also conclude that the disease might be associated with an increase in testosterone levels. Presenting this study is beneficial as there are limited reports about this disease in cats. This is the first study presenting tail gland hyperplasia with some hormonal levels and biochemical parameters in male Van cats.
10

Atropine sulphate test can be an aetiologic indicator of vagal bradycardia developed in a megaoesophagus case

76%
Keles I., Altug N., Kaya A., Ozkan C., Yuksek N., Aslan L.
Bulletin of the Veterinary Institute in Puławy
|
2007
|
tom 51
|
nr 1
An acquired megaoesophagus in a calf has been described. The diagnosis of megaoesophagus was made based on clinical and laboratory examinations, using contrast radiography, and necropsy findings. Atropine sulphate was used to enlighten the relationship between damage in the N. vagus and bradycardia, which developed in the megaoesophagus case.
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