Field trials were carried out on 56 sick sows at private farms. The animals were affected with metritis-mastitis- -agalactiae syndrome or metritis and toxaemia caused by dystocia or retained placenta. Lydium-KLP (NIKA Health Products) was injected intravenously or intramuscularly as: 1) a self-dependent drug once or twice every 24 hours; 2) together with oxytocin; 3) in the form of intramuscular injection of the drug together with antibiotics. The single dose of Lydium-KLP was 0.02 mg/kg of body weight (lysozyme dimer as the active ingredient). The treatment of perinatal disorders with Lydium-KLP resulted in 83.9% recovery of sows. The effectiveness of MMA treatment was more than 90%. It seems that effective therapy should be based on Lydium-KLP administration; antibiotics ought to be applied in case of unsatisfactory findings within 24 hours.