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1

Effect of amino acids on the plasma concentrations and urinary excretion of uric acid and uridine

100%
Yamamoto T., Moriwaki Y., Takahashi S., Tsutsumi Z., Yamakita J. I., Higashino K.
Cellular and Molecular Biology Letters
|
1999
|
tom 04
|
nr 3
2
Content available remote

Clinical significance of urinary glycosaminoglycan excretion in inflammatory bowel disease patients

86%
Derkacz A., Olczyk P., Jura-Poltorak A., Waluga-Kozlowska E., Olczyk K., Komosinska-Vassev K.
Journal of Physiology and Pharmacology
|
2020
|
tom 71
|
nr 6
3

Effect of levels of feed intake on plasma concentration and urinary excretion of purine derivatives in crossbred bulls

72%
George S. K., Dipu M. T., Mehra U. R., Verma A. K., Singh P.
Journal of Animal and Feed Sciences
|
2007
|
tom 16
|
nr 1
26-36
4
Content available remote

Urinary excretion of low molecular weight proteins in goats during the neonatal period

72%
Ozgo M., Skrzypczak W., Drzezdzon D., Lepczynski A., Dratwa-Chalupnik A., Michalek K., Herosimczyk A.
Journal of Physiology and Pharmacology. Supplement
|
2009
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tom 60
|
nr 3
119-125
5

The effect of rumen Protozoa on plasma allantoin level and urinary excretion of purine derivatives in sheep

72%
Fujihara T., Iwakuni M., Shem M. N., Hirano T.
Journal of Animal and Feed Sciences
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2003
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tom 12
|
nr 3
6

Cellular level of 8-oxo-2'-deoxyguanosine in DNA does not correlate with urinary excretion of the modified base nucleoside

72%
Foksinski M., Gackowski D., Rozalski R., Olinski R.
Acta Biochimica Polonica
|
2003
|
tom 50
|
nr 2
We assessed a relationship between the level of 8-oxodG in leukocyte DNA measured with the high performance liquid chromatography with electrochemical detection (HPLC/EC) technique and urinary excretion of the modified nucleoside/base ana­lysed with a recently developed methodology involving HPLC prepurification fol­lowed by gas chromatography with isotope dilution mass spectrometric detection. No correlation was found between these markers of oxidative DNA damage commonly used in epidemiological studies. Several possible explanations of this finding are dis­cussed.
7

Spectrophotometric method for the determination of renal ouabain-sensitive Hplus, Kplus-ATPase activity

72%
Beltowski J., Wojcicka G.
Acta Biochimica Polonica
|
2002
|
tom 49
|
nr 2
The aim of this work was to develop a method for renal H+,K+-ATPase measurement based on the previously used Na+ ,K+ -ATPase assay (Bełtowski et al.: J Physiol Pharmacol.; 1998, 49: 625-37). ATPase activity was assessed by measuring the amount of inorganic phosphate liberated from ATP by isolated microsomal fraction. Both ouabain-sensitive and ouabain-resistant K+ -stimulated and Na+ -independent ATPase activity was detected in the renal cortex and medulla. These activities were blocked by 0.2 mM imidazolpyridine derivative, Sch 28080. The method for ouabain- sensitive H+ ,K -ATPase assay is characterized by good reproducibility, linearity and recovery. In contrast, the assay for ouabain-resistant H ,K -ATPase was unsatisfac­tory, probably due to low activity of this enzyme. Ouabain-sensitive H+ ,K+ -ATPase was stimulated by K + with Km of 0.26 ± 0.04 mM and 0.69 ±0.11 mM in cortex and me­dulla, respectively, and was inhibited by ouabain (Ki of 2.9 ± 0.3 uM in the renal cortex and 1.9 ± 0.4 uM in the renal medulla) and by Sch 28080 (Ki of 1.8 ± 0.5 uM and 2.5 ± 0.9 uM in cortex and medulla, respectively). We found that ouabain-sensitive H+ ,K+ -ATPase accounted for about 12% of total ouabain-sensitive activity in the Na+ ,K+-ATPase assay. Therefore, we suggest to use Sch 28080 during Na+,K+-ATPase measurement to block H+ ,K+ -ATPase and improve the assay specificity. Leptin ad­ministered intraperitoneally (1 mg/kg) decreased renal medullary Na+ ,K+ -ATPase ac­tivity by 32.1% at 1 h after injection but had no effect on H+ ,K+ -ATPase activity sug­gesting that the two renal ouabain-sensitive ATPases are separately regulated.
8

The urinary excretion of purine derivatives in sheep is not influenced by long-term treatment with vasopressin

72%
Faix S., Leng L., Pajak J. J., Czauderna M., Faixova Z., Boldizarova K., Kowalczyk J.
Journal of Animal and Feed Sciences
|
2003
|
tom 12
|
nr 3
9
Content available remote

Evaluation of urinary 6-hydroxymelatonin sulphate excretion in women at different age with irritable bowel syndrome

58%
Wisniewska-Jarosinska M., Chojnacki J., Konturek S., Brzozowski T., Smigielski J., Chojnacki C.
Journal of Physiology and Pharmacology
|
2010
|
tom 61
|
nr 3
295-300
Melatonin (MT) exerts a beneficial action in the treatment of many diseases, among them also in irritable bowel syndrome (IBS). Its secretion decreases with age, particularly, in the postmenopausal period in women. It has not been determined whether these changes can have an impact on the clinical picture of IBS. The study aimed at evaluating the urinary excretion of the main MT metabolite - 6-hydroxymelatonin sulphate (6-HMS) in women at different age with IBS. The investigations were carried out in five groups of 30 women each. Group Ia (the controls) – premenopausal healthy women (20-39 years), group Ib (the controls) – postmenopausal healthy women (46-66 years), group II – women with constipation predominant IBS (IBS-C; 19-42 years), group III – women with diarrhoea predominant IBS (IBS-D; 20-39 years), group IV- women with IBS-C (49-68 years), group V – women with IBS-D (48-69 years). The diagnosis of IBS was based on the Rome III Criteria after excluding other diseases. On the day of the study the patients remained on the same liquid diet (Nutridrink – 3x400 ml) and 1500 ml of still mineral water. 6-HMS concentration in urine was measured by ELISA method applying IBL antibodies (RE-54031, Immunological Laboratories). The results showed that 24-hour urinary 6-HMS excretion in the studied premenopausal women were as follows: group Ia – 15.13±5.83 µg/24 h, group II – 28.85±12.59 µg/24 h (p<0,01), group III – 26.10±11.76 µg/24 h (p<0,01) and in the postmenopausal subjects they were: group Ib – 10.66±3.23 µg/24 h, group IV – 13.73±5.09 µg/24 h ((p=0,02), group V – 21.39±10.88 µg/24 h (p<0,01). In women with IBS-C the obtained results of 24-hour 6-HMS urinary excretion were independent on the intensity of clinical symptoms. On the other hand, in women with IBS-D, both in the group III and V, higher intensity of ailments was accompanied by significantly increased 6-HMS urinary excretion. The results of the study allowed drawing the following conclusions: (1). 24-hour 6-HMS urinary excretion in women with the constipation-predominant (IBS-C) as well as the diarrhoea-predominant IBS (IBS-D) is higher than in healthy persons both in the premenopausal and postmenopausal period. (2). Relatively high 6-HMS urinary excretion in postmenopausal women with IBS-D indicates an adaptive increase in MT secretion from EC in the gut.
10

Urinary excretion of some methylated purine bases in healty subjects

58%
Di Pietro M. C., Liso G., D'Ercole M., Porcelli B., Leoncini R., Mannello E., Vannoni D.
Cellular and Molecular Biology Letters
|
1999
|
tom 04
|
nr 3
11

Urinary excretion of free catecholamines and the concentration of dopamine and serotonin in the plasma of women chronically exposed to carbon disulphide

58%
Stanosz S., Kuligowski D., Pieleszek A., Zuk E., Rzechula D.
Annals of Agricultural and Environmental Medicine
|
1994
|
tom 01
|
nr 1
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