Wyniki wyszukiwania

1

Chemoreceptor and vagal influences on genioglossal muscle responses to inspiratory resistive load

100%

Aleksandrova N. P.

Journal of Physiology and Pharmacology. Supplement

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2004

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tom 55

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nr 3

7-14

The present study was undertaken to determine the mechanisms underlying the involvement of upper airway dilating muscles in compensatory responses to added inspiratory resistive load. Experiments were performed in tracheostomized, anaesthetised rabbits. The effect of inspiratory resistive loading on the electromyographic activity of the genioglossus muscle, the major dilating muscle of the pharynx, was studied in vagotomized and vagally intact rabbits during spontaneous breathing with a hypoxic gas mixture (10% O2 in N2) or oxygen. In the vagally intact animals the peak value and duration of genioglossus muscle inspiratory activity increased in the first loaded breath before any noticeable change in the arterial blood gases. Hyperoxia decreased, whereas hypoxia increased the immediate response of the genioglossus activity to inspiratory loading. Removal of vagal volume-related feedback (by vagotomy) significantly increased the genioglossus muscle activity; the increase being more under hypoxia than under hyperoxia. In contrast to vagally intact animals, there was no first-breath increase in genioglossus activity during loading. The results indicate that the immediate involvement of the genioglossus muscle in response to inspiratory resistive load is mediated by vagal-volume feedback. Baseline oxygen tension before loading modulates the immediate reflex vagal-related response of the genioglossus muscle.

2

Quality of life of patients with diseases of sinuses

67%

Teul I., Zbislawski W., Baran S., Czerwinski F., Lorkowski J.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

3

The incidence of sleep apnea in patients with stroke or transient ischemic attack

67%

Wierzbicka A., Rola R., Wichniak A., Richter P., Ryglewicz D., Jernajczyk W.

Journal of Physiology and Pharmacology. Supplement

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2006

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tom 57

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nr 4

385-390

Disorders of breathing during sleep are defined as cessation or reduction of air flow thorough the upper airway, accompanied by a decrease of oxygen saturation. The results of many studies underline the association between sleep-disordered breathing (SDB) and cerebrovascular disorders. SDB, mostly obstructive sleep apnea syndrome (OSAS), is believed to be an independent risk factor of stroke and is related to poor outcome and increased long-term stroke mortality. The present study evaluated the frequency of SDB in patients with stroke or transient ischemic attack transient ischemic attack. We studied 43 patients (mean age 68.5 ±11.0), which included 35 males and 8 females, with acute stroke (n=37) and transient ischemic attack (n=6). The assessment included body mass index (BMI), age, cardiovascular risk factors, and localization of stroke. All patients underwent all-night screening for SDB with a portable 8-channel recorder. The apnea/hypopnea index (AHI) for the whole group was 13.3 ±15.2. AHI <5 was found in 16 patients. Overall, SDB was present in 27 (62.8%) patients with stroke and transient ischemic attack, stratified into those with AHI 5-10, (10 patients), 10-20 (8 patients), and AHI>20 (9 patients). In 15 patients, there was an increase in AHI 5 on assuming the supine position. The patients’ mean BMI was 27.8 ±4.7. The analysis of BMI, age, and localization of stroke was not sufficient to identify patients with high risk for SDB. We submit that overnight screening for SDB should be routinely performed in every patient after stroke and transient ischemic attack and it should become a diagnostic tool in neurological departments.

4

Action of serotonin on the laryngeal airway in anaesthetized cats

67%

Szereda-Przestaszewska M., Kopczynska B.

Acta Neurobiologiae Experimentalis

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1997

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tom 57

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nr 3

Ograniczanie wyników

3 Journal of Physiology and Pharmacology. Supplement

1 Acta Neurobiologiae Experimentalis

1 Aleksandrova N. P.

1 Baran S.

1 Czerwinski F.

1 Jernajczyk W.

1 Kopczynska B.

1 Lorkowski J.

1 Richter P.

1 Rola R.

1 Ryglewicz D.

1 Szereda-Przestaszewska M.

1 Teul I.

1 Wichniak A.

1 Wierzbicka A.

1 Zbislawski W.

1 2007

1 2006

1 2004

1 1997

Chemoreceptor and vagal influences on genioglossal muscle responses to inspiratory resistive load

Quality of life of patients with diseases of sinuses

The incidence of sleep apnea in patients with stroke or transient ischemic attack

Action of serotonin on the laryngeal airway in anaesthetized cats