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1

Influence of diet and fluoride on dentin and enamel deposition and maturation in rats

100%
Maciejewska I., Adamowicz-Klepalska B., Kmiec Z., Dziewiatkowski J.
Folia Morphologica
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2000
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tom 59
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nr 2
2

Age estimation in Iberian wildcats Felis silvestris, by canine tooth sections

100%
Garcia-Perea R., Baquero R. A.
Acta Theriologica
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1999
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tom 44
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nr 3
We have applied counting of annual cementum lines in canine root to estimate the age of 165 Iberian wildcats Felis silvestris Schreber, 1775. Results indicate that (1) closure of apical foramen of canine root occurs from 6 to 18 months of age, (2) cementum lines are formed in autumn-winter, (3) the first autumn-winter, either a non-continuous line, a continuous "kitten line" or no line can be formed, depending on individual variation in timing of closure of apical foramen, (4) since 7% of wildcats form a kitten line, it needs to be identified in order to avoid an incorrect counting, (5) the first continuous line useful for counting is formed during the second autumn-winter, when animals are 21 months old. For Iberian wildcats, age in years can be estimated by adding 1 to the number of continuous lines. For a more accurate estimation, we propose a formula including months from birth to first line formation, number of annual tines, and months from last line formation to death (A = 9m + Ly + Mm).
3

A novel c.581C-T transition localized in a highly conserved homeobox sequence of MSX1: is it responsible for oligodontia?

100%
Mostowska A., Biedziak B., Trzeciak W. H.
Journal of Applied Genetics
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2006
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tom 47
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nr 2
Even though selective tooth agenesis is the most common developmental anomaly of human dentition, its genetic background still remains poorly understood. To date, familial as well as sporadic forms of both hypodontia and oligodontia have been associated with mutations or polymorphisms of MSX1, PAX9, AXIN2 and TGFα, whose protein products play a crucial role in odontogenesis. In the present report we described a novel mutation of MSX1, which might be responsible for the lack of 14 permanent teeth in our proband. However, this С.581C>Т transition, localized in a highly conserved homeobox sequence of MSX1, was identified also in 2 healthy individuals from the proband’s family. Our finding suggests that this transition might be the first described mutation of MSX1 that might be responsible for oligodontia and showing incomplete penetrance. It may also support the view that this common anomaly of human dentition might be an oligogenic trait caused by simultaneous mutations of different genes.
4
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Capybaras, size, shape, and time: A model kit

80%
Vucetich M. G., Deschamps C. M., Olivares A. I., Dozo M. T.
Acta Palaeontologica Polonica
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2005
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tom 50
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nr 2
The capybaras (Hydrochoeridae) are outstanding rodents for their large size and euhypsodont and multilaminated cheek teeth. Although today they are represented by a single species, it was generally thought that their past diversity was much higher, especially during the late Miocene–early Pliocene. Such diversity is here analyzed taking into account the ontogenetic variation of the p4–m3 in different populations. Numerous isolated teeth of different size found in the upper levels of the Puerto Madryn Formation (late Miocene, Peninsula Valdés, Argentina) were interpreted as members of an ontogenetic series of a new species here described, Cardiatherium patagonicum. They provided clues to evaluate ontogenetic variation and a new framework to analyze the family diversity. In this context, it is proposed that multiple species described from the Ituzaingó Formation (late Miocene, Entre Ríos, Argentina) based on lower teeth, may actually represent specimens of different stages of the ontogenetic trajectory of a single species. Likewise, we found that several nominal taxa from other localities were based on juvenile specimens. According to these results, the diversity of the Hydrochoeridae during the late Miocene and early Pliocene was drastically reduced. The validity of the subfamily Cardiatheriinae is debated. Finally, it is suggested that the whole family should be revised taking into account the ontogenetic variation.
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