Wyniki wyszukiwania

1

The effects of taxol [paclitaxel] on chemiluminescence of neutrophils, macrophages and J.774.2 cell line

100%

Czuba Z. P., Krol W., Hasinski P., Nowowiejska A.

Acta Biochimica Polonica

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1998

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tom 45

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nr 1

Taxol (paclitaxel) is a chemotherapeutic diterpene with promising anticancer activity that blocks cell division by preventing microtubule depolymerization. Furthermore, recent studies have shown that taxol has other intracellular effects that may contribute to its effect, particularly in macrophages. The signal transduction mechanisms by which taxol stimulates macrophages to anticancer activity are not clear. The purpose of this study was to determine the effect of taxol on chemiluminescence (an indicator of the production of free radicals) of neutrophils, macrophages and murine macrophage J.774.2 cells. The chemiluminescence was measured in the presence of taxol andór phorbol myristate acetate (PMA) as a stimulant. Taxol stimulated chemiluminescence (without PMA) of neutrophils and macrophages but not of J.774.2 cells, and modulated chemiluminescence of the cells stimulated with PMA.

2

Tolerance of postoperative chemotherapy involving taxol and cisplatin in ovarian cancer patients

84%

Bednarek W., Mazurkiewicz M., Smolen A., Kotarski J.

Polish Journal of Environmental Studies

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2004

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tom 13

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nr Suppl.2, Part 1

Standard management of ovarian cancer includes cytoreductive surgery and subsequent adjuvant chemotherapy. The purpose of this study was an evaluation of the treatment process and toxicity of taxol and cisplatin in a standard medical procedure for women who underwent a surgery due to ovarian cancer. Participants of our study were 30 women, operated in our department due to ovarian carcinoma. The tolerance of chemotherapy was assessed according to WHO toxicity scale. The answer to the treatment in terms of remission was observed in 80% patients. The results of our study are able to have an important clinical value for future chemotherapy treatment.

3

Peritonitis-induced antitumor activity of peritoneal macrophages from uremic patients

84%

Turyna B., Jurek A., Gotfryd K., Siaskiewicz A., Kubit P., Klein A.

Folia Histochemica et Cytobiologica

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2004

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tom 42

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nr 3

4

Microtubule heterogeneity of Ornithogalum umbellatum ovary epidermal cells: non-stable cortical microtubules and stable lipotubuloid microtubules

67%

Kwiatkowska M., Stepinski D., Polit J. T., Poplonska K., Wojtczak A.

Folia Histochemica et Cytobiologica

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2011

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tom 49

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nr 2

5

Gemcitabine induced cell cycle disturbances and apoptosis in lung cancer cell lines; Basis for combination therapy with topotecan and taxol

67%

Kroep J. R., Giaccone G., Tolis C., Ferreira C. G., Pinedo H. M., Peters G. J.

Cellular and Molecular Biology Letters

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1999

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tom 04

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nr 3

Ograniczanie wyników

2 Folia Histochemica et Cytobiologica

1 Acta Biochimica Polonica

1 Cellular and Molecular Biology Letters

1 Polish Journal of Environmental Studies

1 Bednarek W.

1 Czuba Z. P.

1 Ferreira C. G.

1 Giaccone G.

1 Gotfryd K.

1 Hasinski P.

1 Jurek A.

1 Klein A.

1 Kotarski J.

1 Kroep J. R.

1 Krol W.

1 Kubit P.

1 Kwiatkowska M.

1 Mazurkiewicz M.

1 Nowowiejska A.

1 Peters G. J.

1 Pinedo H. M.

1 Polit J. T.

1 Poplonska K.

1 Siaskiewicz A.

1 Smolen A.

1 Stepinski D.

1 Tolis C.

1 Turyna B.

1 Wojtczak A.

1 2011

2 2004

1 1999

1 1998

The effects of taxol [paclitaxel] on chemiluminescence of neutrophils, macrophages and J.774.2 cell line

Tolerance of postoperative chemotherapy involving taxol and cisplatin in ovarian cancer patients

Peritonitis-induced antitumor activity of peritoneal macrophages from uremic patients

Microtubule heterogeneity of Ornithogalum umbellatum ovary epidermal cells: non-stable cortical microtubules and stable lipotubuloid microtubules

Gemcitabine induced cell cycle disturbances and apoptosis in lung cancer cell lines; Basis for combination therapy with topotecan and taxol