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Effect of cadmium on the prenatal development of hamsters and rats

100%

Minta M., Biernacki B., Wlodarczyk B.

Bulletin of the Veterinary Institute in Puławy

1996

tom 40

nr 1

Hamsters were injected subcutaneously on the 8th gestation day with cadmium chloride at doses of 0, 0.5, 1.O, and 2.0 mg Cd/kg b.w. Rats were treated similarly with single 0, 2 or 3 mg Cd/kg b. w. doses on the 9th gestation day and with a 1 mg dose on the 7th to 10th gestation days. The 1 and 2 mg doses were embryotoxic (inereased number of embryo resorptions), foetotoxic (inhibited embryo growth) and teratogenic (structure malformations of foetuses) in hamster. In contrast, under the conditions used cadmium was neither embryotoxic nor teratogenic to rats even when the dams were treated with subtoxic doses.

Ograniczanie wyników

1 Bulletin of the Veterinary Institute in Puławy

1 Biernacki B.

1 Minta M.

1 Wlodarczyk B.

1 1996

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Effect of cadmium on the prenatal development of hamsters and rats