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Czasopisma help

  1. 4 Journal of Physiology and Pharmacology

  2. 2 Archivum Immunologiae et Therapiae Experimentalis

  3. 2 Bromatologia i Chemia Toksykologiczna

  4. 2 Journal of Physiology and Pharmacology. Supplement

  5. 1 Acta Biochimica Polonica

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Autorzy help

  1. 2 Hoser G.

  2. 2 Pazur A.

  3. 2 Piotrowicz J.

  4. 2 Zachwieja Z.

  5. 1 Aguirre L.

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  1. 1 2019

  2. 1 2017

  3. 1 2015

  4. 1 2013

  5. 3 2012

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1
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Comparative studies on the production of statins using different microbial strains

100%
Syed M. B.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
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2019
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tom 100
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nr 3
2
Content available remote

Short-term changes of serum potassium concentration induced by physical exercise in patients with arterial hypertension treated with angiotensin-converting enzyme inhibitor alone or in combination with statin

100%
Deska P., Nowicki M.
Journal of Physiology and Pharmacology
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2017
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tom 68
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nr 1
3
Content available remote

Atorvastatin does not impair endothelial cell wound healing in an in vitro model of vascular injury

100%
Korybalska K., Kawka E., Breborowicz A., Witowski J.
Journal of Physiology and Pharmacology
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2012
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tom 63
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nr 4
4
Content available remote

Anti-inflammatory effects of atorvastatin treatment in chronic obstructive pulmonary disease. A controlled pilot study

100%
Mroz R. M., Lisowski P., Tycinska A., Bierla J., Trzeciak P. Z., Minarowski L., Milewski R., Lisowska A., Boros P., Sobkowiak B., Duszewska A. M., Chyczewska E., Musial W. J., Macnee W.
Journal of Physiology and Pharmacology
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2015
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tom 66
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nr 1
5
Content available remote

Several statins increase body and liver fat accumulation in a model of metabolic syndrome

80%
Aguirre L., Hijona E., Macarulla M. T., Gracia A., Larrechi I., Bujanda L., Hijona L., Portillo M. P.
Journal of Physiology and Pharmacology
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2013
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tom 64
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nr 3
6

Fluvastatin increases tyrosinase synthesis induced by UVB irradiation of B16F10 melanoma cells

80%
Galus R., Sajjad E., Niderla J., Borowska K., Wlodarski K., Wlodarski P., Jozwiak J.
Folia Histochemica et Cytobiologica
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2009
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tom 47
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nr 3
7
Content available remote

Comparison of a statin vs. hypolipemic diet on the oxidant status in hemodialyzed patients with chronic renal failure

80%
Mastalerz-Migas A., Reksa D., Pokorski M., Steciwko A., Muszynska A., Bunio A., Drobnik J., Pokorna-Kalwak D.
Journal of Physiology and Pharmacology. Supplement
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2007
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tom 58
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nr 5
8
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Influence of some statins on bacteria and actinomyces

80%
Targonski R., Kucharski J., Wyszkowska J.
Journal of Elementology
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2006
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tom 11
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nr 4
In an in uitro experiment the effect of three statins (atorvastatin [Sortis], simvastatin [Zocor], fluvastatin [Lescol]) on the growth of 5 bacterial strains Bacillus subtilis, Bacillus cereus, Proteus vulgaris, Pseudomonas fluorescens, Escherichia coli and 4 saprophytic actinomycetes Streptomyces longisporoflavus, Streptomyces intermedius, Streptomyces odoriver, Streptomyces viridis was tested. The experiments were carried out on solidified substrata with microorganisms covered with filter paper rings soaked with aqueous solution of every tested statin used in different concentrations. It was found that examined substances can inhibit the growth of certain saprophytic microorganisms. Fluvastatin rather than simvastatin or atorvastatin produces stronger effect on bacteria and actinomycetes.
9

Proprotein convertase subtilisin/kexin type 9: A new target molecule for gene therapy

80%
Banaszewska A., Piechota M., Plewa R.
Cellular and Molecular Biology Letters
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2012
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tom 17
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nr 2
Proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as a novel target for controlling plasma levels of low-density lipoprotein cholesterol (LDL-C) and decreasing the risk of cardiovascular diseases. At present it is clear that the major classes of commonly prescribed lipid-lowering medications increase serum PCSK9 levels and fail to protect a significant percentage of patients from cardiovascular events. Therefore development of new LDL-C lowering medications that either do not increase circulating PCSK9 levels or work through inhibition of PCSK9 expression and protease activity is a highly desirable approach to overcome hypercholesterolemia. Since there are several agents which are being evaluated in human preclinical and clinical trials, this review summarizes current therapeutic strategies targeting PCSK9, including specific antibodies, antisense oligonucleotides, small interfering RNAs (siRNAs) and other small-molecule inhibitors.
10

Different statins produce highly divergent changes in gene expression profiles of human hepatoma cells: a pilot study

80%
Leszczynska A., Gora M., Plochocka D., Hoser G., Szkopinska A., Koblowska M., Iwanicka-Nowicka R., Kotlinski M., Rawa K., Kiliszek M., Burzynska B.
Acta Biochimica Polonica
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2011
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tom 58
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nr 4
Statins are inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR), the key enzyme of the sterol biosynthesis pathway. Statin therapy is commonly regarded as well tolerated. However, serious adverse effects have also been reported, especially during high-dose statin therapy. The aim of our study was to investigate the effect of statins on gene expression profiles in human hepatoma HepG2 cells using Affymetrix Human Genome U133 Plus 2.0 arrays. Expression of 102, 857 and 1091 genes was changed substantially in HepG2 cells treated with simvastatin, fluvastatin and atorvastatin, respectively. Pathway and gene ontology analysis showed that many of the genes with changed expression levels were involved in a broad range of metabolic processes. The presented data clearly indicate substantial differences between the tested statins.
11

Immunomodulation by statins: mechanisms and potential impact on autoimmune diseases

80%
Chow S. C.
Archivum Immunologiae et Therapiae Experimentalis
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2009
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tom 57
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nr 4
243-251
12

Sepsis immunopathology: perspectives of monitoring and modulation of the immune disturbances

71%
Skirecki T., Borkowska-Zielinska U., Zlotorowicz M., Hoser G.
Archivum Immunologiae et Therapiae Experimentalis
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2012
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tom 60
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nr 2
13
Content available remote

Therapy of nonalcoholic fatty liver disease: current status

61%
Duvnjak M., Tomasic V., Gomercic M., Smircic Duvnjak L., Barsic N., Lerotic I.
Journal of Physiology and Pharmacology. Supplement
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2009
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tom 60
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nr 7
14

Statyny i ich interakcje z pozywieniem. Cz.I. Lowastatyna i prawastyna

61%
Piotrowicz J., Pazur A., Zachwieja Z.
Bromatologia i Chemia Toksykologiczna
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2008
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tom 41
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nr 3
750-755
15

Statyny i ich interakcje z pozywieniem. Cz.II. Symwastatyna, fluwastatyna, atorwastatyna, rozuwastatyna

61%
Piotrowicz J., Pazur A., Zachwieja Z.
Bromatologia i Chemia Toksykologiczna
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2008
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tom 41
|
nr 4
1023-1029
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