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Developmental changes in endothelium-dependent relaxation of the chicken ductus arteriosus

100%

Agren P., Van Der Sterren S., Cogolludo A. L., Frazziano G., De Mey J. G. R., Blanco C. E., Villamor E.

Journal of Physiology and Pharmacology

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2008

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tom 59

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nr 1

We tested the hypothesis that endothelium-dependent relaxation in the chicken ductus arteriosus (DA) is developmentally regulated. Isolated DA rings from 15-, 19- and 21-day-old (externally pipped) chicken embryos relaxed to acetylcholine (ACh). This relaxation was unaffected by indomethacin but impaired by endothelium removal, by the NO synthase inhibitor L-NAME, and by the soluble guanylate cyclase inhibitor ODQ, suggesting the involvement of NO. This NO production was confirmed with the fluorescent probe DAF-2DA. The combination of apamin and charybdotoxin with L-NAME produced a further inhibition of ACh-induced relaxation, suggesting the participation of a putative EDHF. In the 21-day DA, the relaxations induced by ACh and sodium nitroprusside (SNP) were markedly reduced and scanning electron microscopy demonstrated an irregular endothelial lining with protrusion and detachment of endothelial cells. The relaxations induced by BAY 41-2272 and 8-Br cGMP were not affected by age. When compared with 5%, lower (0%) and higher (21, 95%) O2 concentrations impaired ACh-induced relaxation. In summary, we found that ACh induces endothelium-dependent relaxation of the chicken DA and that NO and EDHF are involved in this response. During chicken DA closure, endothelial cells undergo morphologic and functional alterations that result in the lack of endothelium-dependent relaxation.

2

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Modulation of LDL catabolism by sodium nitroprusside and [PGE2] in human peripheral blood lymphocytes

100%

Miszczuk-Jamska B., Wybranska I., Hartwich J., Dembinska-Kiec A., Gryglewski R. J.

Journal of Physiology and Pharmacology

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1994

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tom 45

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nr 2

3

Enhancing growth in Eucomis autumnalis (Mill.) Chitt. seedlings with exogenous application of nitric oxide

84%

Salachna P., Zawadzinska A., Wierzbinski L., Senderek W.

Journal of Horticultural Research

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2016

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tom 24

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nr 2

4

Cyclic nucleotide-dependent relaxation in human umbilical vessels

84%

Provitera L., Cavallaro G., Griggio A., Raffaeli G., Amodeo I., Gulden S., Lattuada D., Ercoli G., Lonati C., Tomaselli A., Mosca F., Villamor E.

Journal of Physiology and Pharmacology

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2019

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tom 70

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nr 4

5

Sodium nitroprusside stimulates micropropagation and TDZ induces adventitious shoots regeneration in red flesh apple Malus niedzwetzkyana Koehne Dieck ex

84%

Kazemi N., Jafarkhani Kermani M., Habashi A. A.

Journal of Horticultural Research

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2019

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tom 27

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nr 2

6

Involvement of ethylene synthetic inhibitors in regulating the senescence of cut carnations through membrane integrity maintenance

84%

Hassan F., Ali E., Mazrou R.

Journal of Horticultural Research

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2020

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tom 28

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nr 1

7

Nitroso-sulfide coupled signaling triggers specific vasoactive effects in the intrarenal arteries of patients with arterial hypertension

84%

Cacanyiova S., Berenyiova A., Balis P., Kristek F., Grman M., Ondrias K., Breza J., Breza Jr J.

Journal of Physiology and Pharmacology

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2017

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tom 68

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nr 4

8

Bioelectrical activity of the amygdala of rats under conditions of chronic alcoholism and imbalance of nitric oxide

84%

Severynovska O., Babicheva V., Galinskiiy A., Rudenko A., Bogatyreva O., Boyko M.

International Letters of Natural Sciences

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2015

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tom 49

Evaluation of biopotentials in the region of the amygdala of rats in the combined influence of alcohol and drugs, causing an imbalance of nitric oxide is described in this paper. Chronic alcoholism leads to structural morphological changes in the liver. A study of the amplitude of electrical activity showed that the electrical potential in the amygdala after 8 weeks chronic alcoholism was lower compared with normal rats. The frequency spectrum analysis showed decreased in the 2 times or more absolute spectral powers of all components. The relative spectral powers of its components: δ: θ: α: β was as a 2: 2: 2: 4. The use of sodium nitroprusside (donator of NO) together with the chronic consumption of ethanol reduces the effect of ethanol on low and high-frequence portion the performance of the bioelectrical activities spectrum in the amygdala. The use of non-selective blocker of NO-synthase – nitroarginine aggravated by the braking action of alcohol. The important role of nitric oxide in the development of adaptive-compensatory reactions of the damaged body is described. Our results may be useful to assess the contribution of NO in operation amygdala, conditions of chronic pathologies, and treatment of neuropsychiatric conditions, including diseases caused by alcohol abuse.

9

Influence of SIN-1 and sodium nitroprusside [NaNP] on ox-LDL metabolism in macrophages

84%

Wybranska I., Miszczuk-Jamska B., Baczynska E., Goldsztajn P., Sowa G., Przewlocki R., Gryglewski R., Dembinska-Kiec A.

Journal of Physiology and Pharmacology

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1994

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tom 45

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nr 3

10

Influence of diethylenetriamine [DETA] and sodium nitroprusside [NaNP] on sister chromatid exchange frequency and cell kinetics in cultured human lymphocytes

84%

Perkowska M., Szczygiel M., Wozniak A., Limon J.

Journal of Applied Genetics

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2001

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tom 42

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nr 2

11

Role of nitric oxide in the control of the gastric motility within the nucleus ambiguus of rats

67%

Sun H.-Z., Zhao S.-Z., Ai H.-B.

Journal of Physiology and Pharmacology

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2012

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tom 63

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nr 6

12

Response of strawberry "Selva" plants on foliar application of sodium nitroprusside (nitric oxide donor) under saline conditions

67%

Jamali B., Eshghi S., Kholdebarin B.

Journal of Horticultural Research

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2014

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tom 22

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nr 2

13

Sodium nitroprusside, a nitric oxide donor, fails to bypass the block of neuronal differentiation in PC12 cells imposed by a dominant negative Ras protein

67%

Bator J., Varga J., Berta G., Barbakadze T., Mikeladze D., Ramsden J., Szeberenyi J.

Cellular and Molecular Biology Letters

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2012

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tom 17

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nr 3

Nitric oxide (NO) is a mediator of a diverse array of inter- and intracellular signal transduction processes. The aim of the present study was to analyze its possible role as a second messenger in the process of neuronal differentiation of PC12 pheochromocytoma cells. Upon NGF treatment wildtype PC12 cells stop dividing and develop neurites. In contrast, a PC12 subclone (designated M-M17-26) expressing a dominant-negative mutant Ras protein keeps proliferating and fails to grow neurites after NGF treatment. Sodium nitroprusside (SNP), an NO donor, was found to induce the p53 protein and to inhibit proliferation of both PC12 and M-M17-26 cells, but failed to induce neuronal differentiation in these cell lines. Key signaling pathways (the ERK and Akt pathways) were also not affected by SNP treatment, and the phosphorylation of CREB transcription factor was only slightly stimulated. It is thus concluded from the results presented in this paper that NO is unable to activate signaling proteins acting downstream or independent of Ras that are required for neuronal differentiation.

14

Effect of ischemic preconditioning on endothelial dysfunction and granulocyte adhesion in isolated guinea-pig hearts subjected to ischemia-reperfusion

67%

Kurzelewski M., Czarnowska E., Maczewski M., Beresewicz A.

Journal of Physiology and Pharmacology

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1999

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tom 50

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nr 4

15

Apoptotic effect of reactive oxygen-nitreogen species [ROS-RNS] in rat L6 satellite cells

67%

Orzechowski A., Grzelkowska K.

Polish Journal of Veterinary Sciences

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2000

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tom 03

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nr 4

We previously demonstrated that both mitogenicity and anabolism in rat L6 myoblasts even in the presence of insulin could be markedly reduced by milimolar concentrations of H202, SIN-1 (3-mor- pholinosydnonimine) and SNP (sodium nitroprusside) - donors of peroxynitrite (ONOO ) and nitric oxide (NO), respectively (Orzechowski and Grzelkowska 2000). In this paper we described the results of the experiment, which was carried out in order to confirm the assumption that muscle cell death occurred after treatment with high (milimolar) doses of ROS/RNS. Hydrogen peroxide (H202) or SIN-1, or SNP, all induced cell death in rat L6 myoblasts when given at 1 mM. Symptoms of cell shrinking with nuclear chromatin condensation collapse of chromatin into patches along nuclear membrane and formation of apoptotic bodies occurred within 24 hours of the study. Apoptosis was evaluated in situ on the basis of apoptotic index. The process of oligonucleosomal fragmentation of nuclear DNA was demonstrated whenever apoptotic cell death was observed. The verification of cell viability was monitored and the above-mentioned index confirmed the lack of cell respiration in dead myoblasts, especially those treated with SNP. On average 92%, 80%, 77% and 65% of cells were found apoptotic after 1 mM H202, 1 mM SIN-1 or 0.5 mM SNP and 1 mM SNP, respectively. However, necrotic cell death significantly contributed to overall cell death in cultures treated with NO donor and amounted to 6% and 21% for 0.5 mM SNP and 1 mM SNP, respectively. Taken together, these results indicate massive apoptosis induced by H202 and SIN-1, but, with regard to apoptotic action of NO, cell respiration was additionally attenuated and associated with necrotic cell death.

16

Influence of sodium nitroprusside NO-donor on psychotropic activity of angiotensin II

67%

Wisniewski K., Holy Z.

Journal of Physiology and Pharmacology

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1995

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tom 46

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nr 2

17

The effect of nitric oxide donors on the release of plasminogen activator inhibitor [PAI] from rabbit platelets in vitro

67%

Korbut R., Marcinkiewicz E., Cieslik K., Gryglewski R. J.

Journal of Physiology and Pharmacology

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1995

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tom 46

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nr 1

18

The effects of male gender and female sex hormone deficiency on the vascular responses of the rat in vitro

59%

Nevala R., Paakkari I., Tarkkila L., Vapaatalo H.

Journal of Physiology and Pharmacology

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1996

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tom 47

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nr 3

Ograniczanie wyników

Developmental changes in endothelium-dependent relaxation of the chicken ductus arteriosus

Modulation of LDL catabolism by sodium nitroprusside and [PGE2] in human peripheral blood lymphocytes

Enhancing growth in Eucomis autumnalis (Mill.) Chitt. seedlings with exogenous application of nitric oxide

Cyclic nucleotide-dependent relaxation in human umbilical vessels

Sodium nitroprusside stimulates micropropagation and TDZ induces adventitious shoots regeneration in red flesh apple Malus niedzwetzkyana Koehne Dieck ex

Involvement of ethylene synthetic inhibitors in regulating the senescence of cut carnations through membrane integrity maintenance

Nitroso-sulfide coupled signaling triggers specific vasoactive effects in the intrarenal arteries of patients with arterial hypertension

Bioelectrical activity of the amygdala of rats under conditions of chronic alcoholism and imbalance of nitric oxide

Influence of SIN-1 and sodium nitroprusside [NaNP] on ox-LDL metabolism in macrophages

Influence of diethylenetriamine [DETA] and sodium nitroprusside [NaNP] on sister chromatid exchange frequency and cell kinetics in cultured human lymphocytes

Role of nitric oxide in the control of the gastric motility within the nucleus ambiguus of rats

Response of strawberry "Selva" plants on foliar application of sodium nitroprusside (nitric oxide donor) under saline conditions

Sodium nitroprusside, a nitric oxide donor, fails to bypass the block of neuronal differentiation in PC12 cells imposed by a dominant negative Ras protein

Effect of ischemic preconditioning on endothelial dysfunction and granulocyte adhesion in isolated guinea-pig hearts subjected to ischemia-reperfusion

Apoptotic effect of reactive oxygen-nitreogen species [ROS-RNS] in rat L6 satellite cells

Influence of sodium nitroprusside NO-donor on psychotropic activity of angiotensin II

The effect of nitric oxide donors on the release of plasminogen activator inhibitor [PAI] from rabbit platelets in vitro

The effects of male gender and female sex hormone deficiency on the vascular responses of the rat in vitro