Wyniki wyszukiwania

1

On the role of ball and chain interactions in recovery from the inactivation of the shaker potassium channel

100%

Borys P., Grzywna Z. J.

Cellular and Molecular Biology Letters

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2008

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tom 13

|

nr 4

526-534

We describe a new factor in the recovery from inactivation in the ball and chain model. We propose a model in which the tension from the chain may help pull the ball away from its binding site, reducing the duration of the inactivation period. A corresponding model was built and analysed.

2

Expression of ENaC, SGK1 and Nedd4 isoforms in the cochlea of guinea pig

86%

Zhong S.-X., Hu G.-H.

Folia Histochemica et Cytobiologica

|

2014

|

tom 52

|

nr 2

3

Adaptation to cypermethrin [pyrethroids] in Periplaneta americana L.

86%

Tyczynski M.

Acta Biologica Cracoviensia. Series Zoologia

|

2009

|

tom 51

63-72

4

Adaptation to permethrin in Periplaneta americana L.

86%

Tyczynski M.

Pestycydy

|

2005

|

nr 4

99-116

5

Do pesticides affect the thermal behaviour in Amphibia?

86%

Grajpel B., Tegowska E.

Pestycydy

|

2004

|

nr 3-4

6

Insect sodium channels as targets for arthropod toxins - electrophysiological studies

72%

Stankiewicz M., De Lima M. E., Ciolek J., Pelhate M.

Pestycydy

|

2005

|

nr 3

87-93

7

Evidence for state-dependent block of DPI 201-106, a synthetic inhibitor of Na+ channel inactivation, on delayed-rectifier K+ current in pituitary tumor (GH3) cells

72%

Wang Y.-J., Lin M.-W., Lin A.-A., Peng H., Wu S.-N.

Journal of Physiology and Pharmacology

|

2008

|

tom 59

|

nr 3

409-423

DPI 201-107 (DPI), a diphenylpiperazinylindole derivative, was reported to be a cardio-selective modifier of voltage-gated Na+ channels. It remains unclear whether DPI has any effects on ion currents. The effects of DPI on ion currents and membrane potential in pituitary tumor (GH3) cells were investigated in this study. DPI (1-100 µM) suppressed the amplitude of delayed-rectifier K+ current (IK(DR)) in a concentration-dependent manner with an IC50 value of 9.4 µM. The presence of DPI also enhanced the rate and extent of IK(DR) inactivation. Recovery from block by DPI (10 µM) was fitted by a single exponential. Crossover of tail currents during the exposure to DPI was also observed. Under current-clamp recordings, DPI prolonged action potential duration in GH3 cells. With a minimal binding scheme, DPI-induced block of IK(DR) was quantitatively provided. The exposure to DPI also blocked IK(DR) with a concomitant increase in current inactivation in NG108-15 neuronal cells. Taken together, the results imply that DPI acts as an open-channel blocker of delayed-rectifier K+ channels in these cells. The widening of action potentials induced by DPI in these cells may be explained mainly by its block of IK(DR) in a state-dependent manner.

8

Tetrodotoxin blocks native cardiac L-type calcium channels but not Cav1.2 channels expressed in HEK cells

72%

Szentandrassy N., Papp F., Hegyi B., Bartok A., Krasznai Z., Nanasi P. P.

Journal of Physiology and Pharmacology

|

2013

|

tom 64

|

nr 6

9

Influence of bifenthryne [pyrethroid] on the chosen behavioural and physiological parameters in Periplaneta americana L. with consideration of the detoxication process

72%

Tyczynski M., Przybylska E.

Pestycydy

|

2004

|

nr 3-4

10

Mutational screening of SCN5A linked disorders in Polish patients and their family members

72%

Moric-Janiszewska E., Herbert E., Cholewa K., Filipecki A., Trusz-Gluza M., Wilczok T.

Journal of Applied Genetics

|

2004

|

tom 45

|

nr 3

11

Ionic mechanisms involved in the nodal swelling of myelinated axons caused by marine toxins

58%

Benoit E., Mattei C., Ouanounou G., Meunier F. A., Suput D., Le Gall F., Marquais M., Dechraoui M. Y., Molgo J.

Cellular and Molecular Biology Letters

|

2002

|

tom 07

|

nr 2

This review describes the ionic mechanisms involved in the nodal swelling of frog myelinated axons caused by specific marine neurotoxins (ciguatoxins, brevetoxins, Conus consors toxin and equinatoxin-II), analysed using confocal laser scanning microscopy. We have focussed on toxins that either target neuronal voltage-dependent Na+ channels, or that form cation-selective pores and indirectly affect the functioning of the Na+-Ca++ exchanger.

12

The insect sodium channel as the target for insect selective neurotoxins from scorpion venom

51%

Zlotkin E., Moskowitz H., Herrmann R., Pelhate M., Gordon D.

Biophysics of Membrane Transport

|

1994

|

tom 12

|

nr 2

Ograniczanie wyników

On the role of ball and chain interactions in recovery from the inactivation of the shaker potassium channel

Expression of ENaC, SGK1 and Nedd4 isoforms in the cochlea of guinea pig

Adaptation to cypermethrin [pyrethroids] in Periplaneta americana L.

Adaptation to permethrin in Periplaneta americana L.

Do pesticides affect the thermal behaviour in Amphibia?

Insect sodium channels as targets for arthropod toxins - electrophysiological studies

Evidence for state-dependent block of DPI 201-106, a synthetic inhibitor of Na+ channel inactivation, on delayed-rectifier K+ current in pituitary tumor (GH3) cells

Tetrodotoxin blocks native cardiac L-type calcium channels but not Cav1.2 channels expressed in HEK cells

Influence of bifenthryne [pyrethroid] on the chosen behavioural and physiological parameters in Periplaneta americana L. with consideration of the detoxication process

Mutational screening of SCN5A linked disorders in Polish patients and their family members

Ionic mechanisms involved in the nodal swelling of myelinated axons caused by marine toxins

The insect sodium channel as the target for insect selective neurotoxins from scorpion venom