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Chemerin and the recruitment of NK cells to diseased skin

100%

Skrzeczynska-Moncznik J., Stefanska A., Zabel B. A., Kapinska-Mrowiecka M., Butcher E. C., Cichy J.

Acta Biochimica Polonica

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2009

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tom 56

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nr 2

355-360

Natural killer (NK) cells play a major role in the initial control of many viral pathogens and in the rejection of tumors. Consistent with their roles as immune sentinels, NK cells are found in inflamed skin, including lichen planus, psoriasis and atopic dermatitis (AD) lesions. In oral lichen planus lesions, the recruitment as well as intradermal colocalization of NK cells and pDC (plasmacytoid dendritic cells) appear to be mediated by chemerin, a recently identified protein ligand for chemokine-like receptor 1 (CMKLR1), a chemoattractant receptor expressed by both cell types. Dendritic cells can regulate NK cell activity, and NK cells can regulate DC-mediated responses. Since chemerin was recently implicated in recruitment of pDC to psoriatic skin, in this work we determined whether chemerin facilitates interactions between NK and pDC in psoriatic plaques through controlling influx of NK cells to diseased skin. We demonstrate that circulating NK cells from normal donors as well as psoriasis and AD patients respond similarly in functional migration assays to chemerin. However, differences in the distribution of NK cells and pDC in skin lesions suggest that recruitment of both NK cells and pDC is unlikely to be controlled solely by chemerin.

2

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Ivermectin vs. lindane in the treatment of scabies

86%

Goldust M., Rezaee E., Raghifar R., Naghavi-Behzad M.

Annals of Parasitology

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2013

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tom 59

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nr 1

Scabies is commonly treated with acaricides but the treatment of choice is still controversial. This study aimed at comparing the efficacy of oral ivermectin vs. lindane lotion 1% for the treatment of scabies. Four hundred fourty patients with scabies were enrolled, and randomized into two groups: the first group received a single dose of oral ivermectin 200 μg/kg body weight, and the second group were treated with two applications of topical lindane lotion 1%, with a 1-week interval. Treatment was evaluated at intervals of 2 and 4 weeks, and if there was treatment failure at the 2-week follow-up, treatment was repeated. Single dose of oral ivermectin provided a cure rate of 63.6% at the 2-week follow-up, which increased to 81.8% at the 4-week follow-up after repeating the treatment. Treatment with two applications of lindane lotion 1%, with a 1-week interval between them, was effective in 45.4% of patients at the 2-week follow-up, which increased to 63.6% at the 4-week follow-up after this treatment was repeated. Single dose ivermectin was as effective as two applications of lindane lotion 1% at the 2-week follow-up. After repeating the treatment, ivermectin was superior to lindane lotion 1% at the 4-week follow up.

3

Overcoming the challenge; In Vivo efficacy of miltefosine for chronic cutaneous leishmaniasis

86%

Tunali V., Harman M., Cavus I., Gunduz C., Ozbilgin A., Turgay N.

Acta Parasitologica

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2021

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tom 66

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nr 2

4

Is atopic dermatitis a response to Malassezia overgrowth in dogs?

86%

Dworecka-Kaszak B., Kaszak I., Dabrowska I.

Annals of Parasitology

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2016

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tom 62

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nr Suppl.

5

Dermocosmetics for atopic skin care available in pharmacies on Polish market

86%

Malinowska P.

Towaroznawcze Problemy Jakości. Polskie Towarzystwo Towaroznawcze

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2015

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nr 4

6

Efficient plant regeneration of bittersweet [Solanum dulcamara L.], a medicinal plant

86%

Mutlu E. C., Turker A. U.

Acta Societatis Botanicorum Poloniae

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2008

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tom 77

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nr 4

275-280

Solanum dulcamara L. (bittersweet) is a medicinal plant that has been used to treat skin diseases, warts, tumors, felons, arthritis, rheumatism, bronchial congestion, heart ailments, ulcerative colitis, eye inflammations, jaundice and pneumonia. A reliable in vitro culture protocol for bittersweet was established. Explants (leaf and petiole segments) were cultured on Murashige and Skoog minimal organics (MSMO) medium with various plant growth regulator combinations. Leaf explants formed more shoots than petiole explants. Plant regeneration was observed through indirect organogenesis with both explants. Best shoot proliferation was obtained from leaf explants with 3 mg/l BA (benzyladenine) and 0.5 mg/l IAA (indole-3-acetic acid). Regenerated shoots were transferred to rooting media containing different levels of IAA (indole-3-acetic acid), IBA (indole-3-butyric acid), NAA (naphthalene acetic acid) or 2,4-D (2,4 dichlorophenoxyacetic acid). Most shoots developed roots on medium with 0.5 mg/l IBA. Rooted explants were transferred to vermiculate in Magenta containers for acclimatization and after 2 weeks, they were planted in plastic pots containing potting soil and maintained in the plant growth room.

7

Cattle derived skin diseases and other zoonoses in Finnish farmers

86%

Susitaival P., Seuri M.

Annals of Agricultural and Environmental Medicine

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1994

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tom 01

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nr 2

8

Correlation of HLA-Cw 06 allele frequency with some clinical features of psoriasis vulgaris in the population of Northern Poland

86%

Szczerkowska-Dobosz A., Rebala K., Szczerkowska Z., Witkowska-Tobola A.

Journal of Applied Genetics

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2004

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tom 45

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nr 4

9

Increasing frequency of cercarial dermatitis at higher latitudes

86%

Larsen A. H., Bresciani J., Buchmann K.

Acta Parasitologica

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2004

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tom 49

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nr 3

The number of cercarial dermatitis (swimmer’s itch) cases in the Nordic countries has been increasing during the latest years. Thus, records from Iceland, Norway, Sweden and Denmark have occurred at increasing frequencies. In order to elucidate the biological basis for this infection of ten species of pulmonate snails in some Danish lakes were monitored in 2003. Ocellate cercariae belonging to the genera Trichobilharzia and Bilharziella were recorded in 1.3% and 0.71% of all snails examined, respectively. However, in specific snail hosts the prevalences recorded were up to 50%. The biotic and abiotic factors responsible for the observations are discussed, but the relatively high prevalence of infected snails in the present study calls for further monitoring of these pathogenic cercariae in European freshwater localities.

10

Occupational dermatoses in farmers - a proposal for diagnostic procedure

86%

Spiewak R.

Annals of Agricultural and Environmental Medicine

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1999

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tom 06

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nr 1

11

Application of IPL technology in acne vulgaris treatment: a case report

72%

Koziolek A., Chilicka K.

Medical Science Pulse

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2018

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tom 12

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nr 2

Background: Intense pulsed light (IPL) technology has been used by cosmetic and medical practitioner since 1990. Initially it was only used to remove unnecessary hair, but over time, it began to be used for anti-aging treatments, removing erythema, acne lesions, and acne scars. Aim of the study: The aim of this study is to investigate how the use of IPL technology has affected acne lesions and to determine whether the condition of the patient’s skin has improved. Material and methods: A young woman who was struggling with ordinary acne underwent a series of treatments using IPL technology to reduce skin eruptions. Results: The study subject was a 22-year-old patient who had been suffering from acne vulgaris for several years. The skin on her face exhibited changes in the form of pustules, blackheads, and lumps. The entire treatment series was 10 weeks. Prior to the procedure, a very thorough interview was conducted, during which all contraindications were excluded. The Hellgren-Vincent scale, which is used to determine the severity of acne lesions, accurately determines the amount of skin lesions in the form of lumps, pustules, and blackheads. Conclusions: As demonstrated by this study, IPL technology has been beneficial for the condition of the patient’s skin. Pictures from before and after unambiguously indicate the positive effect of intense pulsed light. There has been great improvement in the skin’s overall condition, with reduced acne lesions (lumps, pustules, blackheads).

12

Interleukin-25, thymic stromal lymphopoietin and house dust mites in pathogenesis of atopic dermatitis

72%

Jaworek A. K., Szafraniec K., Zuber Z., Wojas-Pelc A., Jaworek J.

Journal of Physiology and Pharmacology

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2020

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tom 71

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nr 2

13

Current problems concerning parasitology and mycology with regard to diseases of the skin and its appendages

72%

Blaszkowska J., Wojcik A.

Annals of Parasitology

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2012

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tom 58

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nr 3

Current issues concerning Parasitology and Mycology with regard to diseases of the skin and its appendages are presented. Aspects of diagnostics, clinical picture and therapy of skin and nail mycoses, as well as difficulties in the diagnosis and treatment of both native parasitoses (toxoplasmosis) and imported human tropical parasitoses (malaria, filariosis) have been emphasised. The clinical importance of environmental mould fungi in nosocomial infections and fungal meningitis, as well as selected properties of fungi isolated from patients with head and neck neoplasms treated by radiotherapy are discussed. Other mycological topics include the characteristics of newlysynthesized thiosemicarbazides and thiadiazoles as potential drugs against toxoplasmosis and their biological activity against Toxoplasma gondii tachyzoites, selected molecular mechanisms of resistance to azoles, Candida albicans strains and a new tool (barcoding DNA) for describing the biodiversity of potential allergenic molds. The importance of environmental factors in pathogenesis of mycoses and parasitoses is noted. The characteristics of pathogenic fungi isolated from natural ponds in Bialystok and potentially pathogenic yeast-like fungi isolated from children’s recreation areas in Lodz are presented. The ongoing problem of anthropozoonoses is considered, as are the roles of stray cats and dogs in contaminating soil with the developing forms of intestinal parasites. The characteristics of the human microbiome, including population composition, activity and their importance in normal human physiology, are presented, as are the major goals of the Human Microbiome Project initiated by National Institutes of Health (NIH).

14

Molecular detection and seasonal distribution of lumpy skin disease virus in cattle breeds in Turkey

72%

Albayrak H., Ozan E., Kadi H., Cavunt A., Tamer C., Tutuncu M.

Medycyna Weterynaryjna

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2018

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tom 74

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nr 03

The aim of this study was to investigate the prevalence and distribution patterns of LSDV infections in the provinces of northern Turkey, and to detect the factors influencing the epidemiology of LSD virus infections (age, breed, season, climate, geography, population dynamic, animal movement), as well as to assess the diagnostic value of the sampled materials in the diagnosis of LSDV infections. Lumpy skin disease (LSD) is an economically important cattle disease. The disease is endemic in many African countries, but outbreaks have also been reported in Turkey and the Middle East. In this study, a total of 564 samples (skin, blood and lung) from different cattle breeds (Jersey, Holstein-Friesian, Anatolian Black, Simmental and Brown Swiss) (n = 465) in the many herds suspected of lumpy skin disease virus (LSDV) infection as clinically and macroscopic pathologic remarks, housed in the 7 different provinces of northern Turkey, were used for gel based conventional polymerase chain reaction (PCR). LSDV nucleic acid was detected in 259 of 564 (45.92%) materials by PCR. According to the result of PCR, the LSDV infection was diagnosed in 54.62% (254/465) of the sampled animals. The diagnostic value of necropsy and clinical materials such as skin and lung were determined as more valuable diagnostic materials in the diagnosis of LSDV infection by PCR. Data showed that LSDV infection was widespread in the provinces of northern Turkey and that the prevalence of the infection in the region varies in accordance with factors such as geographical conditions (climate, season, location etc.) and the method of breeding.

15

Trigonella foenum-graecum seeds in treatment of metabolic syndrome

72%

Kania-Dobrowolska M., Baraniak J.

Herba Polonica

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2020

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tom 66

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nr 3

16

Vozbuzhdenie kolebanijj v prizmaticheskom rezonatore s pomoshh'ju prjamougol'nogo volnovoda

72%

Potapskijj P., Garasimchuk I., Panzir Y.

Motrol. Motoryzacja i Energetyka Rolnictwa

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2015

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tom 17

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nr 5

17

Chemokine (C-X-C motif) ligand 1 (CXCL1) and chemokine (C-X-C motif) ligand 2 (CXCL2) modulate the activity of TRPV1+/IB4+ cultured rat dorsal root ganglia neurons upon short-term and acute application

72%

Deftu A. F., Filippi A., Shibasaki K., Gheorghe R. O., Chiritoiu M., Ristoiu V.

Journal of Physiology and Pharmacology

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2017

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tom 68

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nr 3

18

Systemic treatment for severe atopic dermatitis

72%

Giavina-Bianchi M., Giavina-Bianchi P.

Archivum Immunologiae et Therapiae Experimentalis

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2019

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tom 67

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nr 2

19

Human microbiome: composition and role in inflammatory skin diseases

72%

Balato, Cacciapuoti S., Di Caprio R., Marasca C., Masara A., Raimondo A., Fabbrocini G.

Archivum Immunologiae et Therapiae Experimentalis

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2019

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tom 67

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nr 1

20

Retinoids as an immunity-modulator in dermatology disorders

72%

Chen W., Zhao S., Zhu W., Wu L., Chen X.

Archivum Immunologiae et Therapiae Experimentalis

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2019

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tom 67

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nr 6

Ograniczanie wyników

Chemerin and the recruitment of NK cells to diseased skin

Ivermectin vs. lindane in the treatment of scabies

Overcoming the challenge; In Vivo efficacy of miltefosine for chronic cutaneous leishmaniasis