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Effect of TAT-signaling fusion system along with co-expression of GroEL/ES chaperones on secretory expression of somatropin

100%

Rabbani M., Ghasemi R., Bagherinejad M. R., Jahanian A.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

2020

tom 101

nr 2

Prediction of signal peptides in protein sequences by neural networks

100%

Plewczynski D., Slabinski L., Ginalski K., Rychlewski L.

Acta Biochimica Polonica

2008

tom 55

nr 2

261-267

We present here a neural network-based method for detection of signal peptides (abbreviation used: SP) in proteins. The method is trained on sequences of known signal peptides extracted from the Swiss-Prot protein database and is able to work separately on prokaryotic and eukaryotic proteins. A query protein is dissected into overlapping short sequence fragments, and then each fragment is analyzed with respect to the probability of it being a signal peptide and containing a cleavage site. While the accuracy of the method is comparable to that of other existing prediction tools, it provides a significantly higher speed and portability. The accuracy of cleavage site prediction reaches 73% on heterogeneous source data that contains both prokaryotic and eukaryotic sequences while the accuracy of discrimination between signal peptides and non-signal peptides is above 93% for any source dataset. As a consequence, the method can be easily applied to genome-wide datasets. The software can be downloaded freely from http://rpsp.bioinfo. pl/RPSP.tar.gz.

How are plastid proteins of the apicomplexan parasites imported? A hypothesis

72%

Bodyl A.

Acta Protozoologica

1999

tom 38

nr 1

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Acta Protozoologica

1 BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

1 Bagherinejad M. R.

1 Bodyl A.

1 Ghasemi R.

1 Ginalski K.

1 Jahanian A.

1 Plewczynski D.

1 Rabbani M.

1 Rychlewski L.

1 Slabinski L.

1 2020

1 2008

1 1999

Wyniki wyszukiwania

Effect of TAT-signaling fusion system along with co-expression of GroEL/ES chaperones on secretory expression of somatropin

Prediction of signal peptides in protein sequences by neural networks

How are plastid proteins of the apicomplexan parasites imported? A hypothesis