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Salicylate intolerance is defined as a nonspecific antigen-induced pseudo-allergic hypersensitivity reaction which can occur upon contact of an organism with salicylic acid, its derivatives or other related organic or inorganic acids of similar chemical structure. Since the effects of nonsteroidal anti-inflammatory drugs (NSAID) intolerance are by no means always severe or life-endangering but may just as well present as oligosymptomatic or local disorders (e.g. abdominal pain, diarrhea, we decided to evaluate the characteristics of patients with salicylate intolerance on the basis of gastroenterological case material of Medical Department I of Erlangen University. On the basis of the findings from the Erlangen interdisciplinary data register of chronic inflammatory gastrointestinal disease, the signs and symptoms of NSAID intolerance were found to constitute a diagnosis of great practical import to clinical medicine (allergology, dermatology, immunology, other disorders etc.) including gastroenterology. For approx. 2-7% of all patients with inflammatory bowel syndrome and food allergies this poses a new diagnostic and therapeutic challenge which may concern physicians from any of the disciplines involved. When presented with patients with chronic active disease who are suffering from these symptoms one should, therefore, in future give greater thought to the possibility of salicylate intolerance, all the more as there are meaningful dietetic, diagnostic and therapeutic options available for these persons.
The current survey aimed to study the effect of exogenous salicylic acid (SA) application on salinity stress of grapevine cv. ’Sultana’. The leaves of hydroponically cultivated grapes that were under 0, 75 and 150 mM salinity conditions treated with 0, 0.5, 1 and 1.5 mM SA and after two weeks, the factors such as Na+, K+, proline and MDA contents, leaf electrolyte leakage and enzymatic activities were measured. The results showed that all SA treatments were significantly effective at tolerance enhancement by reduction in Na+/K+ ratio, leaf electrolyte leakage, MDA and H2O2 values and promotion in proline content and the enzymatic activities (POD, APX, CAT and SOD) of grapes. These results indicated that SA application at salinity condition could be applied as a promising method for increasing the salinity tolerance of ‘Sultana’ grapes.
Salicylic acid (SA), a key signaling molecule in higher plants, has been found to play a role in the response to a diverse range of phytopathogens and is essential for the establishment of both local and systemic-acquired resistance. Recent studies have indicated that SA also plays an important role in abiotic stress-induced signaling, and studies on SA-modulated abiotic tolerance have mainly focused on the antioxidant capacity of plants by altering the activity of anti-oxidative enzymes. However, little information is available about the molecular mechanisms of SA-induced abiotic stress tolerance. Here, we review recent progress toward characterizing the SA-regulated genes and proteins, the SA signaling pathway, the connections and differences between SA-induced tolerances to biotic and abiotic stresses, and the interaction of SA with other plant hormones under conditions of abiotic stress. The future prospects related to molecular tolerance of SA in response to abiotic stresses are also further summarized.
Salicylic acid (SA) applied at concentrations from 1–10 µg·ml⁻¹ to germinating seeds of 8 barley cultivars reduced the disease rating of seedlings. Seedlings of barley not treated with SA and inoculated with Fusarium culmorum exhibited disease rating of root on avarage 76 %. Seedlings treated before inoculation with solution of SA 1, 2, 5 and 10 µg/ml exhibited significantly lower disease rating: on average 66, 58, 44 and 38 %. Disease score of leaf decreased in similar extent: from 30 % to 20, 11, 7 and 0 %.
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