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Using the enzymatic test based on measurement of glutathione reductase activity in haemolysates the vitamin B2 nutrition status was assessed twice at an interval of 5 years in 57 elderly women and 42 men living in family homes in Warsaw. The first study was carried out in 1992 when the study group had reached the age of 70 years, the second study was done in 1997 when the age of 75 years had been reached by the group. Normal vitamin B2 nutrition status (a BGR < 1.20) was found in 1997 in a greater proportion of the study group (96.5% women and 100% men) as compared to the results in 1992 (86.0% women and 78.6% men). The medium vitamin B2 deficiency risk (a BGR = 1.20-1.28) was found in 1992 in 8.7% women and 14.3% men, while in 1997 it was noted in only 3.5% of women. In 1997 no case of high deficiency risk was found (a BGR - 1.29 or more) while in 1992 it was demonstrated in 5.3% and 7.1% of women and men respectively. The analysis of history data concerning vitamin B2 supplements intake showed that the proportion of persons taking those supplements has risen from 17.5% in 1992 to 21.1% in the group of women and from 19.0% to 33.3% in the group of men between 1992 and 1997.
The aim of this study was to evaluate the activity of antioxidant enzymes in horses diagnosed with recurrent airway obstruction (RAO). The study was conducted on a group of 40 horses, various breeds, divided into two groups, aged 8-15 years, including 15 males and 25 mares. Blood was collected for antioxidant analyses from 20 recurrent airway obstruction (RAO)-affected horses and 20 healthy control horses. The authors determined the activity of glutathione reductase, glutathione peroxidase and glutathione S-transferase in the blood. Average reductase activity in a group of healthy horses was 79.7 U/g, while in the group of RAO-affected horses it was 39.7 U/g. The average activity of glutathione peroxidase in the group of healthy horses was 47.8 U/g, while in the group of RAO-affected horses it was 37.8 U/g. The average activity of glutathione S-transferase in the group of healthy horses was 39.8 U/g, while in the group of RAO-affected horses it was 21.8 U/g. The resulting research indicates that oxidative stress is a consequence of chronic airway inflammation in the course of RAO in horses.
The significance of mangane as an environmental pollutant has increased in previous years. In this study the authors present the influence of chronic exposure of mangane on oxidative stress parameters. Depending on the position in the brain, the authors observed the following changes: decrease of GPx and GR activity in the brain stem, similarly in the cerebellum; in the brain’s hemispheres, however, an increase of GST activity and a decrease of GR activity was observed. CAT activity in all these three structures remained at a lower, constant level.
Badano wpływ selenu podawanego w postaci drożdży selenowych na procesy oksydacyjne w doświadczalnej hipercholesterolemii indukowanej podawaniem masy jajecznej u królików.
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