The purpose of these studies was to assess the involvement of nNOS and iNOS inhibitors on stress fever caused by exposure to an open field in freely moving biotelemetered rats. Vinyl-L-NIO (N5 - (1-Imino-3-butenyl) - ornithine, a neural nitric oxide synthase (nNOS) inhibitor, and aminoguanidine, an inducible nitric oxide synthase (iNOS) inhibitor, were injected into the lateral ventricle (icv) at a dose of 5 µg and 10 µg, respectively, and then immediately exposed to open field for 30 min. After exposure to the open field, rats not treated with NOS inhibitors responded with a rapid rise in Tb and it was accompanied with an increase of motor activity. Both inhibitors significantly suppressed the stress fever. vL-NIO did not influence stress-induced rise in locomotor activity as well as did not change Tb in unstressed rats. Since aminoguanidine caused a transient fall in Tb below the baseline in rats exposed or not to open field and because this inhibitor suppressed stress-induced rise in locomotor activity, we concluded that nNOS expression inside the brain is critically involved in the rise in Tb due to exposure to psychological stress.
In our paper we have concentrated on determination of the influence of plastification on changes of properties of aspen wood for the purpose of its shaping. We were concentrated on the bendability, density and the stability of compressed wood.
The purpose of this work was to characterize some physico-chemical properties of proteins in raw and stored Tibo faba beans. The storage caused that the faba bean proteins were partialy degraded and hydrolysed, which resulted in a decreased content of albumins, globulins, and amino acids in stored seeds. The nutritional value of proteins decreased due to loss of essential amino acids and lower susceptibility of the proteins to proteolytic enzymes. Opposite to globulins, trypsin released more non-protein nitrogen from albumins than pepsin. The yield of extraction of albumins and globulins decreased upon storage and some modification in the protein conformations, most probably due to aggregation, dissociation and glycation, could have been hypothesized.