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1

Estiamtion of BrdUrd-independent sister chromatid exchanges and proliferation rate of human lymphocytes in vitro

100%
Kotecki M., Pawlak A. L.
Bulletin of the Polish Academy of Sciences. Biological Sciences
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1989
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tom 37
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nr 10-12
2

Evaluation of the immunomodulatory activity of four compounds exerting antimutagenic effects on human lymphocytes in vitro

100%
Gasiorowski K., Brokus B., Tabaka H.
Cellular and Molecular Biology Letters
|
2000
|
tom 05
|
nr 4
469-481
Four compounds previously described as antimutagenic for human lymphocytes in vitro were tested on their immunomodulatory activity in lymphocyte cultures. The standard immunocytochemical methods were applied for microscopic examination of the percentual representation of the main lymphocyte subpopulation. The results imply that all of the tested compounds exhibited significant immunomodulatory effect, with that of fluphenazine being the strongest, whereas that of todralazine is the weakest. Two of the tested compounds: anthocyanins from Aronia melanocarpa fruit, and alkylresorcinols from cereal grains, also exhibited a distinct immunomodulatory activity, and it deserves adequate attention as an activity exerted by natural products, commonly present in regular human diet. The analysis of the proliferating cell fraction, and the estimation of the cell proliferation rate suggest that the effect of the tested compounds might depend on an increase in the number of lymphocytes which expressed their differentiation antigens on the cell membranes.
3

Ki-67 labelling index in human brain tumours

100%
Niemiec J.
Folia Histochemica et Cytobiologica
|
2001
|
tom 39
|
nr 3
4

Effect of gastric Helicobacter-like organisms on gastric epithelial cell proliferation rate in dogs

100%
Sapierzynski R., Malicka E.
Polish Journal of Veterinary Sciences
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2004
|
tom 07
|
nr 4
The aim of this study was the evaluation of gastric epithelial cell proliferation rate in connection with the gastric Helicobacter-like organisms (GHLO) infection in dogs. The study was performed on samples of the gastric mucosa obtained during necropsies from 60 dogs euthanasized for various reasons. Microscopic preparations were stained with the hematoxylin-eosin method, Giemsa method, Warthin-Starry silver method and immunohistochemical method (MIB-1 antibody) to investigate the expression Ki67 antigen. In glands of the gastric body and antrum different proliferation patterns were observed. The gastric epithelial cell proliferation rate in the gastric antrum was significantly higher in dogs with GHLO colonization in relation to dogs without GHLO, and in the gastric body was significantly higher in dogs with mild GHLO colonization as compared to dogs with significant GHLO colonization and without GHLO colonization. The gastric epithelial cell proliferation rate in the gastric body was significantly higher in dogs with gastritis in comparision with the dogs without gastritis irrespectively from the presence or absence of the GHLO colonization. It seems that the presence of the GHLO colonization, as well as the inflammatory state in the gastric mucosae, can alter the rate of the gastric epithelial cells proliferation in dogs.
5

The comparison of primordial germ cell populations in embryos of KE and CBA inbred strains of mice

84%
Wabik-Sliz B., Paczuska I., Wisniewska A., Lenartowicz M.
Folia Histochemica et Cytobiologica
|
1998
|
tom 36
|
nr 2
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