Wyniki wyszukiwania

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Antilymphocyte globulin with a small dose of cyclosporine A and prednisone as the induction of immunosuppression in renal allograft recipients

100%

Boratynska M., Szepietowski T., Szewczyk Z., Szydlowski Z.

Archivum Immunologiae et Therapiae Experimentalis

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1992

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tom 40

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nr 2

2

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The evaluation of canine atopic dermatitis extent and severity index (CADESI) test in dogs with atopic dermatitis (AD) treated with cyclosporine or prednisone

84%

Taszkun I.

Polish Journal of Veterinary Sciences

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2010

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tom 13

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nr 4

The purpose of this study was to assess the clinical state of dogs with atopic dermatitis (AD) by use of CADESI test in own modification during the first visit in the Dermatology Consult Room as well as during the treatment. The study was performed in two groups (I-E and II-C) of 20 dogs in each group. In dogs which were qualified to the I-E group, as antiallergic, anti-inflammatory and antipruritic treatment, prednisone (oral preparation Encorton – Polfa Pabianice) at dose 0.5 mg/kg b.w./day was administered, while in dogs qualified to the II-C group – cyclosporine (oral preparation Sandimmun Neoral – Novartis Pharma) at a dose of 5 mg/kg b.w./day; the treatment was continued for 6 weeks in both groups. During the study, skin lesions were assessed in 15 specified body areas using 4 parameters and 5-point scale. In group I-E and II-C the amount of received points in CADESI test was decreased by 82.26% and by 83% respectively, after the treatment. Statistical analyses of the results obtained revealed no statistically significant (P=0.05) differences between means of I-E and II-C groups in consecutive examinations, which indicates comparable clinical efficacy of both drugs. Statistically significant differences (P=0.05) of the parameters assessed were found after secondary dermatoses treatment, and after every two weeks of antipruritic and anti-inflammatory treatment.

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Assessment of pruritus using pruritus score test in dogs with atopic dermatitis treated with cyclosporine or prednisone

67%

Taszkun I.

Bulletin of the Veterinary Institute in Puławy

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2010

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tom 54

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nr 4

The purpose of this study was to evaluate the suitability of pruritus score test in pruritus diagnosis in dogs. The test was used to assess the frequency and severity of pruritus in dogs between 1 and 3 years of age, suffering from atopic dermatitis. Skin pruritus was assessed: during the first visit (examination 0), after elimination of secondary dermatosis (examination 1), 2 weeks after the treatment with prednisone - group I-E or cyclosporine - group II-C (examination 2) as well as 6 weeks after treatment (examination 3). In examination 0, the skin pruritus in all dogs was scored at 26.75%. Reduction of pruritus was observed during the treatment in examination 3 in dogs of group I-E (by 80.46%) and in dogs of group II-C (by 86.12%) in comparison with examination 0. Localisation of pruritus in particular body parts was also examined, resulting in observation that in examination 0 it was mostly found in interdigital space of front paws, facial part of the muzzle, chin, ears but not always with the same intensity in symmetrically placed body parts. Mean values of the measurement were statistically significant (P≤0.005) after 2, 4, and 6 weeks of the treatment in I-E and II-C groups. No statistically significant differences were observed between I-E and II-C groups in consecutive measurements.

Ograniczanie wyników

1 Archivum Immunologiae et Therapiae Experimentalis

1 Bulletin of the Veterinary Institute in Puławy

1 Polish Journal of Veterinary Sciences

2 Taszkun I.

1 Boratynska M.

1 Szepietowski T.

1 Szewczyk Z.

1 Szydlowski Z.

2 2010

1 1992

Antilymphocyte globulin with a small dose of cyclosporine A and prednisone as the induction of immunosuppression in renal allograft recipients

The evaluation of canine atopic dermatitis extent and severity index (CADESI) test in dogs with atopic dermatitis (AD) treated with cyclosporine or prednisone

Assessment of pruritus using pruritus score test in dogs with atopic dermatitis treated with cyclosporine or prednisone