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1

Pyrrolizidine alkaloids

100%
Ronczka S., Speer K.
Polish Journal of Food and Nutrition Sciences
|
2011
|
tom 61
|
nr Suppl.1
2
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Neuroprotective strategies using vegetal compounds in the treatment of Alzheimer’s disease

75%
Loredana S., Alin C., Radu L., Daniel T., Emil A.
International Letters of Natural Sciences
|
2015
|
tom 45
Lately, different therapy strategies for treating or slowing the progression of Alzheimer's disease are being analyzed. Moreover, the last two decades have seen a considerable research effort directed towards discovering the causes of Alzheimer's disease with the ultimate hope of developing safe and effective pharmacological treatments. In addition to the therapeutic strategies based on targeted drugs, the regimens will require the simultaneous application of neuroprotective drugs. Therefore, although there is currently no "cure" for Alzheimer's disease, a large number of potential therapeutic strategies emerged lately. In this small mini-review we will selectively describe some of the compounds derived from plants that could have a great potential in the treatment of various diseases, including Alzheimer's disease. In this way, there are many plant species that have been traditionally used for memory disorders. The differentiated results and powerful activity of these extracts are making these neuroprotective strategies to be somehow plausible for the treatment of Alzheimer's disease. In addition, these plants can be examined in order to isolate and identify their active ingredients and this can serve as a starting point to find safer and more effective agents for therapeutic use. On thing is certain: as the effective treatment options are limited, there is a demand for new drugs. Thus, plant extracts or vegetal compounds could represent an important part in this equation.
3

Synergy between novel antimicrobials and conventional antibiotics or bacteriocins

63%
Wolska K. I., Grzes K., Kurek A.
Polish Journal of Microbiology
|
2012
|
tom 61
|
nr 2
Due to the alarming spread of resistance to classic antimicrobial agents, innovative therapeutic methods to combat antibiotic-resistant bacterial pathogens are urgently required. This minireview examines the enhancement of antibiotic efficacy by their combination with new antimicrobials, such as plant-derived compounds, metal ions and nanoparticles and bacteriophage lytic enzymes. The mechanisms of the observed synergy are also described. The promising results of basic research indicate that in future, combined therapy may be applied in human and veterinary medicine, agriculture and the food industry to combat bacterial pathogens.
4

Control of wilt and root rot incidence in Phaseolus vulgaris L. by some plant volatile compounds

51%
El-Mougy N. S., El-Gamal N. G., Abdel-Kader M. M.
Journal of Plant Protection Research
|
2007
|
tom 47
|
nr 3
255-266
Essential oils from four plants, i.e. geranium, rosa, lemon and mint were tested for their activity in vitro and in vivo against Rhizoctonia solani and Fusarium oxysporum f. sp. phaseoli, the cause of root rot and wilt of beans. In vitro, they were found to have an inhibitory effect against the mycelial growth of R. solani and F. oxysporum f. sp. phaseoli. Complete inhibition in fungal growth was observed at a concentration of 4% of each essential oil and Topsin M at 400 ppm as well. In greenhouse the four essential oils were tested as seed coating and/or foliar spray. Results of seed coating at a concentration of 1% clearly demonstrate a good protection of emerged bean seeds against invasion of R. solani and F. oxysporum f. sp. phaseoli compared with the fungicide treatment. A similar trend was observed in a lower extent when the essential oils were applied as bean seeds coating followed by seedlings foliar spray under field conditions. Obvious yield increase as bean green pods, in all treatments, was significantly higher than in the control.
5

New antibacterial therapeutics and strategies

51%
Kurek A., Grudniak A., Kraczkiewicz-Dowjat A., Wolska K.
Polish Journal of Microbiology
|
2011
|
tom 60
|
nr 1
Studies on new antibacterial therapeutics and strategies are currently being conducted in many microbiological, pharmaceutical and biochemical laboratories. The antibacterial activity of plant-derived compounds as well as silver and gold nanoparticles is the subject of this minireview. The application of photodynamic therapy is also discussed.
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