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Antimicrobial activity of Ficus sycomorus L. (Moraceae) leaf and stem-bark extracts against multidrug resistant human pathogens

100%

Saleh B., Hammoud R., Al-Mariri A.

Herba Polonica

2015

tom 61

nr 1

The present work was conducted to investigate antibacterial activity of methanol and acetone in leaf (LE) and stem-bark (SBE) of Ficus sycomorus L. crude extracts against sensitive and resistant species of Staphylococcus aureus and Acinetobacter baumannii pathogens. Antimicrobial activity expressed by disc-diffusion method (zone of inhibitions – ZIs), minimum inhibitory concentrations (MICs) and minimum bactericidal concentration (MBC) were measured as reported for many investigations. Similar study with 6 commercial antibiotics as a reference drug was undertaken. Based upon the estimated ZIs, MIC and MBC values, acetone LE exhibited higher antimicrobial activity than that of methanol one. Otherwise, standard antibiotics have lower effectiveness (ZIs, MICs and MBC) on all tested bacteria as compared to the SBE and LE. The highest antibacterial activity was recorded in sensitive A. baumannii isolate with MICs 2.5, 4.9 mg/ml and MBC 3.8, 9.7 mg/ml for acetone LE and SBE, respectively. Our data indicated that the lowest antibiotics antibacterial activity was recorded for resistant A. baumannii pathogen. It was lower than those of the both plant fractions extracts.

Plastoquinone: possible involvement in plant disease resistance

80%

Maciejewska U., Polkowska-Kowalczyk L., Swiezewska E., Szkopinska A.

Acta Biochimica Polonica

2002

tom 49

nr 3

The plant Solanum nigrum treated with the pathogen Phytophthora infestans-de- rived elicitor responded by elevated reactive oxygen species (ROS) production, lipid peroxidation and lipoxygenase (EC 1.13.11.12) activity in comparison with control plants indicating that oxidative stress took place. We demonstrate that these events are accompanied by a significant increase in plastoquinone (PQ) level. It is postulated that PQ may be associated with mechanisms maintaining a tightly controlled balance between the accumulation of ROS and antioxidant activity that determines the full expression of effective defence.

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Herba Polonica

1 Al-Mariri A.

1 Hammoud R.

1 Maciejewska U.

1 Polkowska-Kowalczyk L.

1 Saleh B.

1 Swiezewska E.

1 Szkopinska A.

1 2015

1 2002

Wyniki wyszukiwania

Antimicrobial activity of Ficus sycomorus L. (Moraceae) leaf and stem-bark extracts against multidrug resistant human pathogens

Plastoquinone: possible involvement in plant disease resistance