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Usefulness of calcium-magnesium products in parturient paresis in HF cows

100%

Sobiech P., Rypula K., Wojewoda-Kotwica B., Michalski S.

Journal of Elementology

2010

tom 15

nr 4

693-704

The increased milk yield in dairy cattle has made it increasingly difficult to balance accurately the feed ration. This results in energy and mineral deficiencies as well as various homeostasis disorders including calcium and magnesium balance disorders, which in turn lead to metabolic disorders. In our study, we chose to assess the therapeutic efficacy of two most popular products of this type i.e. Glucalvet (Vetoquinol Biowet) and Antiparen-N (Vetoquinol Biowet). The study was conducted on 33 HF cows dipslaying symptoms of postparturient paresis that occurred between 2 and 4 day postpartum. The cows were divided into two groups: group A and group B, which were administered Glucalvet and Antiparen-N, respectively. Blood samples were taken twice from the jugular vein of each animal – just before and 24 hours after drug administration. The samples were used to determine serum concentrations of Ca, Mg, P, Cl and glucose. The average body temperature in both groups was slightly below normal and statistically significantly increased 24 hours after the intravenous infusion. The same tendency was observed for the pulse rate. The magnesium levels in the first group improved significantly after drug administration but its level was still lower than the physiological range. In the second group of animals, a slight drop in the Mg level after the Antiparen-N administration. Levels of Ca and P increased in both group of animals after the treatment. The average chloride concentration was similar for both assays. The serum glucose concentration increased significantly in both groups of animals after drug administration. Summing up, the study presented in this paper indicates that Glucalvet and Antiparen-N prove to be useful in the treatment of post-parturient paresis conditioned by Ca and Mg deficiency.

Influence of novel intravenous complex solution of Ca, Mg and phosphates on blood biochemical parameters of healthy and paretic cows

67%

Daunoras G., Dabuzinskas S., Matusevicius A., Cernauskas A.

Polish Journal of Veterinary Sciences

2008

tom 11

nr 1

17-23

The article describes the dynamics of changes in blood concentrations of the active substances present in the solution after its infusion to healthy cows in comparison to NaCI solution as well as the response of paretic cows to treatment with the new complex solution. Cows received a dose of 400 ml of Al solution (containing 8.4 g of Ca2+) intravenously. In healthy cows the average calcium concentration in blood serum prior to the test was 2.52 + 0.08 mmol/1 while 15 min. after the infusion the concentration rose to 3.10 ± 0.08 mmol/1 (p < 0.05) and magnesium concentration rose from 0.61 ± 0.05 to 1.39 ± 0.08 mmol/1 (p < 0.05). This experiment showed that elevated concentration of non-organic phosphates persisted 1 hour after infusion (p < 0.05). In the second phase of efficacy evaluation of the novel preparation Al on paretic cows the intravenous injection of 1 ml/kg of body weight of Al solution increased calcium concentration up to almost normal level (p < 0.05). The level of magnesium in serum 1 h after injection was statistically significantly higher by 63% (p < 0.05) and reached the physiologically normal concentration. 1 h after the infusion of test solution the level of phosphate was higher by 13% (p > 0.05). The rise was statistically not significant. Even though Al solution undoubtedly produced an increase in glucose concentration in the blood serum, due to wide dispersion of individual measurements and high standard deviation the increase (p > 0.05) in glucose concentration was found insignificant. Most of the treated paretic cows rose within 1-6 h after infusion of 400 ml of solution Al. No relapses were observed. A combination of different salts of calcium and magnesium, non-organic phosphates and glucose with analeptic substance mixed in one solution (Al solution) administered at a dose of 1 ml/kg of body weight raises concentrations of essential macroelements in blood serum of cattle and promotes improvement of paretic cows condition.

Ograniczanie wyników

1 Journal of Elementology

1 Polish Journal of Veterinary Sciences

1 Cernauskas A.

1 Dabuzinskas S.

1 Daunoras G.

1 Matusevicius A.

1 Michalski S.

1 Rypula K.

1 Sobiech P.

1 Wojewoda-Kotwica B.

1 2010

1 2008

Wyniki wyszukiwania

Usefulness of calcium-magnesium products in parturient paresis in HF cows

Influence of novel intravenous complex solution of Ca, Mg and phosphates on blood biochemical parameters of healthy and paretic cows