Wyniki wyszukiwania

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Molekularne mechanizmy nowotworzenia Papillomaviridae u zwierzat i ludzi

100%

Szczerba-Turek A., Szweda W., Siemionek J., Platt-Samoraj A., Bancerz-Kisiel A., Teodorowski P.

Medycyna Weterynaryjna

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2007

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tom 63

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nr 09

1045-1048

Papillomaviruses (PV) are small, nonenveloped, DNA viruses, which had originally been grouped together with the Polyomaviruses in one family, Papovaviridae. In the year 2004 the International Committee on the Taxonomy of Viruses officially recognized two separate families: Papillomaviridae and Polyomaviridae. PV are pathogens of skin and mucosa in animals and humans, and they are very species-specific. The only known case of cross-species infection is the infection of horses by bovine papillomaviruses (BPV) type 1 and 2. Infection by high-risk types of human papillomaviruses (HPV) such as HPV type 16 and 18 is directly related to the subsequent development of cervical carcinoma in women. In the year 1995 The International Agency for Research on Cancer officially declared, that HPV-16 and HPV-18 are carcinogenic for humans. Animal PV cause various diseases in both farm and companion animals, e.g. skin and teat papillomatosis in cattle, canine oral papillomatosis, oesophageal papillomas and carcinoma in cattle and equine sarcoids. The mechanisms of carcinogenesis caused by PV were initially established using animal models and specifically chosen PV, particularly cottontail rabbit papillomavirus (CRPV), BPV and canine oral papillomavirus (COPV). In the paper the organization and structure of the PV genome, the characteristics of early and late regions, enzymatic and regulatory proteins, encoded by specific open reading frames and engaged in virus replication process, as well as structural proteins that take part in virus-cell interaction have been discussed. The replication process of PV and mechanisms of carcinogenic transformation of cells infected with PV were also described. The possibility of the implementation of specific immunoprophylaxis and the necessity of improvement of diagnostic methods, as well as conducting molecular comparative studies of human and animal PV, important for the protection of animal health and public health, have been indicated.

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Kliniczne typy sarkoidow koni

51%

Szczerba-Turek A., Siemionek J., Ras A., Platt-Samoraj A., Mikulska-Skupien E., Bancerz-Kisiel A., Szweda W.

Medycyna Weterynaryjna

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2009

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tom 65

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nr 12

827-829

Equine sarcoids have been recognized for centuries, but were first characterized by Jackson in 1936. The term sarcoid was originally used to emphasize the clinical and pathological differences from papilloma, fibroma and fibrosarcoma. Sarcoids are the most common skin tumors in horses. They tend to be locally aggressive but they do not metastasize. They affect horses of all ages, types and hair colours without obvious sex predilection and they are commonly encountered worldwide. Sarcoids are recognized as having six different clinical types: verrucose, fibroblastic, occult, nodular, mixed and malignant. All of them can occur at any skin site. The mechanisms of equine sarcoid development are not clear, but papillomaviruses (PV) - BPV-1 and less commonly BPV-2, which belong to the Papillomaviridae family - participate in etiopathogenesis. All PV are strictly species-specific and, even in experimental conditions, do not infect other species. The only known case of cross-species infection is the infection of horses and other Equidae by BPV-1 and BPV-2.

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Papillomawirusy: HPV jako czynnik etiologiczny nowotworów głowy i szyi

51%

Wicinski K., Leis K., Malinowski B., Weclewicz M. M., Grzesk E., Grzesk G.

Postępy Mikrobiologii

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2018

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tom 57

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nr 1

4

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Wirusy onkogenne w etiopatogenezie nowotworów zwierząt

51%

Chodkowski M., Brzezicka J., Golke A., Slonska A., Cymerys J.

Życie Weterynaryjne

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2017

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tom 92

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nr 10

5

Przypadek brodawczycy

51%

Przywara K., Jawor P., Rzasa A.

Weterynaria w Terenie

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2009

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tom 03

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nr 4

6

Choroby skóry wywołane przez wirusy i pierwotniaki

38%

Sikorska-Kopylowicz A., Jonkisz P., Nicpon J., Misztal A.

Weterynaria w Praktyce

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2013

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tom 10

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