The activity of glucose catabolism pathways of film-forming strains of staphylococci isolated from vagina of women with dysbiosis of reproductive tract and from women without disorders of microflora was studied. It was established that the investigated film-forming strains utilized the carbohydrates by pentose phosphate pathway mainly, as indicated by 23-33% higher enzyme activity compare to strains isolated from healthy women. Instead strains, isolated from women without dysbiosis of reproductive tract, have higher activity of glycolytic enzymes on 13- 28%. The prevalence of glycolytic transformation of glucose by strains isolated from healthy women also indicates by the depression of glucose oxidation during action of monoiodinacetate – classical inhibitor of glycolysis. It inhibits glycolysis of strains isolated from healthy women more significant. It was established that oxidase activity of film-forming strains isolated from women with dysbiosis, increased over 40% during the use of basic substrates of citric acid cycle. These data indicate a general increase of catabolic activity of oxidative type of staphylococci isolated during vaginal dysbiosis and able to form biofilm.
The influence of cinnamic acid, 1-tryptophane, 3,4-dihydroxyphenylalanine, 2,4-dichlorophenol modifying IAA-oxidase activity and indoleacetic acid on the development and reproduction of cereal aphids in laboratory conditions was tested. We observed that IAA and Try stimulated the reproduction of cereal aphids whereas CA, DOPA and DCP decreased it.